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TLR5 Antibody (19D759.2) [DyLight 350]

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Product Details

Summary
Reactivity Hu, Mu, CaSpecies Glossary
Applications WB, DB, Flow, ICC/IF, IHC, IP
Clone
19D759.2
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 350

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-24787AF350
Alexa Fluor 405
NBP2-24787AF405
Alexa Fluor 488
NBP2-24787AF488
Alexa Fluor 532
NBP2-24787AF532
Alexa Fluor 594
NBP2-24787AF594
Alexa Fluor 647
NBP2-24787AF647
Alexa Fluor 700
NBP2-24787AF700
Alexa Fluor 750
NBP2-24787AF750
Allophycocyanin
NBP2-24787APC
Allophycocyanin/Cy7
NBP2-24787APCCY7
Biotin
NBP2-24787B
DyLight 405
NBP2-24787V
DyLight 488
NBP2-24787G
DyLight 550
NBP2-24787R
DyLight 594
NBP2-24787DL594
DyLight 650
NBP2-24787C
DyLight 680
NBP2-24787FR
DyLight 755
NBP2-24787IR
FITC
NBP2-24787F
HRP
NBP2-24787H
Janelia Fluor 549
NBP2-24787JF549
Janelia Fluor 646
NBP2-24787JF646
PE
NBP2-24783
PE/Atto594
NBP2-24787PEATT594
PE/Cy5.5
NBP2-24787PECY55
PE/Cy7
NBP2-24787PECY7
PerCP
NBP2-24787PCP
Unconjugated
NBP2-24787
mFluor Violet 450 SE
NBP2-24787MFV450
mFluor Violet 500 SE
NBP2-24787MFV500
mFluor Violet 610 SE
NBP2-24787MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-24787
BSA Free
NBP2-24787
BSA Free
NBP2-24787SS
Azide and BSA Free
NBP2-80981
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TLR5 Antibody (19D759.2) [DyLight 350] Summary

Description
This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
Immunogen
This antibody was developed against KLH-conjugated synthetic peptide corresponding to a portion of human TLR5 between amino acids 700-800. The antibody also reacts with mouse TLR5.
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
TLR5
Purity
Protein G purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Dot Blot
  • Flow (Cell Surface)
  • Flow (Intracellular)
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Agonist

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for TLR5 Antibody (19D759.2) [DyLight 350]

  • MGC126430
  • MGC126431
  • SLEB1FLJ10052
  • TIL-3
  • TIL3Toll/interleukin-1 receptor-like protein 3
  • TLR5
  • toll-like receptor 5

Background

The Toll like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules and could constitute an important and unrecognized component of innate immunity in humans. The TRL family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. TLRs characterized so far activate the MyD88/interleukin 1 receptor-associated kinase (IRAK) signaling pathway. Toll-like receptor 5 (TLR5) expression is upregulated following exposure to bacteria or to the TLR5 agonist, flagellin. Gram-negative bacteria, stimulate monocyte/macrophage cells in a TLR5-specific, CD14-independent manner. The TLR5 receptor thus appears to be the principal means by which the innate immune system recognizes flagellated bacterial pathogens.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol TLR5