Recombinant Human TL1A/TNFSF15 Protein

This lyophilized preparation is stable at 2-8 degrees C, but should be kept at -20 degrees C for long term storage, preferably desiccated. Upon reconstitution, the preparation is most stable at -20 to -80 degrees C, and can be stored for one week at 2-8 degrees C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 degrees C to -80 degrees C. Avoid repeated freeze/thaw cycles.

TL-1A is a type II transmembrane protein belonging to the TNF superfamily and has been designated TNF superfamily member 15 (TNFSF15). TL-1A is predominantly expressed in endothelial cells and its expression is inducible by TNF-alpha and IL-1alpha. TL- 1A binds with high affinity to death receptor 3 (DR3), known as TNFRSF25. Depending on the cell context, ligation of DR3 by TL-1A can trigger one of two signaling pathways, activation of the transcription factor NF-kB, or activation of caspases and apoptosis. Recombinant human TL-1A is a 20.5 kDa polypeptide of 180 amino acid residues.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Array NBP2-35067

• TL1A/TNFSF15 Antibodies
• TL1A/TNFSF15 Lysate
• TL1A/TNFSF15 Proteins
• TL1A/TNFSF15 ELISAs
• TL1A/TNFSF15 Proteins and Enzymes