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TL1A/TNFSF15 Antibody (2116A) [DyLight 594]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, IHC, B/N, CyTOF-ready
Clone
2116A
Clonality
Monoclonal
Host
Rabbit
Conjugate
DyLight 594

Order Details

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TL1A/TNFSF15 Antibody (2116A) [DyLight 594] Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
E. coli-derived recombinant human TL1A/TNFSF15
Leu72-Leu251
Accession # O95150
Specificity
Detects human TL1A/TNFSF15 in direct ELISAs.
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Purity
Protein A or G purified from cell culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Immunohistochemistry
  • Neutralization
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from cell culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for TL1A/TNFSF15 Antibody (2116A) [DyLight 594]

  • MGC129934
  • MGC129935
  • TL1A
  • TL1Vascular endothelial cell growth inhibitor
  • TNF superfamily ligand TL1A
  • TNFSF15
  • tumor necrosis factor (ligand) superfamily, member 15
  • tumor necrosis factor ligand superfamily member 15
  • vascular endothelial growth inhibitor-192A
  • VEGI
  • VEGI192A
  • VEGITNF ligand-related molecule 1

Background

VEGI is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. An additional isoform encoded by an alternatively spliced transcript variant has been reported but the sequence of this transcript has not been determined

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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