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Substance P Antibody (SR2325)

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Immunohistochemistry-Paraffin: Substance P Antibody (SR2325) [NBP3-27852] - Immunohistochemical analysis of paraffin-embedded human brain
Immunohistochemistry-Paraffin: Substance P Antibody (SR2325) [NBP3-27852] - Immunohistochemical analysis of paraffin-embedded human brain

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clone
SR2325
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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Substance P Antibody (SR2325) Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
A synthesized peptide derived from human Substance P (Uniprot #: P20366)
Specificity
Detects endogenous levels of total Substance P
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
TAC1
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50-1:200

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4), 150mM NaCl, 50% glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for Substance P Antibody (SR2325)

  • neurokinin 1
  • neurokinin 2
  • neurokinin A
  • Neurokinin-1
  • neuromedin L, neurokinin alpha, neuropeptide K, neuropeptide gamma)
  • neuropeptide gamma
  • neuropeptide K
  • NK2
  • NKA
  • NKNAneurokinin alpha
  • NPK
  • PPT
  • protachykinin-1
  • substance K
  • Substance P
  • TAC1
  • TAC2neuromedin L
  • tachykinin 2
  • tachykinin, precursor 1 (substance K, substance P, neurokinin 1, neurokinin 2
  • tachykinin, precursor 1

Background

The tachykinins belong to an evolutionary conserved family of peptide neurotransmitters that share the c-terminal sequence Phe-X-Gly-Leu-Met-NH2 and have an established role in neurotransmission. The mammalian tachykinins include substance P, neurokinin A (NKA) and neurokinin B (NKB) which exert their effects by binding to specific receptors. Tachykinin peptides are important in the mediation of many physiological and pathological processes including inflammation, pain, migraine headache and allergy induced asthma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol TAC1