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SOX4 Antibody (PCRP-SOX4-1D6) [Janelia Fluor® 635]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, ICC/IF, IHC, IP, MA
Clone
PCRP-SOX4-1D6
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 635

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SOX4 Antibody (PCRP-SOX4-1D6) [Janelia Fluor® 635] Summary

Immunogen
Recombinant fragment (around aa45-130) of human SOX4 protein (Uniprot: Q06945)
Localization
Nucleus
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
SOX4
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
  • Protein Array
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Predicted to react in Xenopus and Chicken.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for SOX4 Antibody (PCRP-SOX4-1D6) [Janelia Fluor® 635]

  • ecotropic viral integration site 16
  • EVI16
  • SRY (sex determining region Y)-box 4
  • SRY-related HMG-box gene 4
  • transcription factor SOX-4

Background

SOX4 encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for SOX4 Antibody (NBP3-14180JF635) (0)

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Secondary Antibodies

 

Isotype Controls

Additional SOX4 Products

Array NBP3-14180JF635

Research Areas for SOX4 Antibody (NBP3-14180JF635)

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Blogs on SOX4.

Bad news for stomach cancer: BAMBI protein inhibits gastric carcinoma via TGF-beta/epithelial-mesenchymal transition signaling
By Jamshed Arslan Pharm.D. Gastric carcinoma is the second leading cause of cancer-related deaths worldwide. One of the key features of gastric carcinoma is acidosis, which promotes growth and metastasis of gastric ...  Read full blog post.

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Bioinformatics

Gene Symbol SOX4