| Reactivity | HuSpecies Glossary |
| Applications | WB |
| Clonality | Polyclonal |
| Host | Goat |
| Conjugate | Unconjugated |
| Concentration | LYOPH |
| Immunogen | E. coli-derived recombinant human SOX5 Met417-Asn763 Accession # P35711 |
| Specificity | Detects endogenous human SOX5 in Western blots. |
| Source | N/A |
| Isotype | IgG |
| Clonality | Polyclonal |
| Host | Goat |
| Gene | SOX5 |
| Purity Statement | Antigen Affinity-purified |
| Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
| Dilutions |
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| Publications |
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| Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
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| Buffer | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS. |
| Preservative | No Preservative |
| Concentration | LYOPH |
| Reconstitution Instructions | Reconstitute at 0.2 mg/mL in sterile PBS. |
SOX5 (SRY-related HMG box) is a 75‑80 kDa Group D member of the SOX family of DNA-binding proteins. It is expressed in fetal chondrocytes and skeletal muscle, with a short form appearing in spermatids. SOX5 form homodimers and heterodimerizes with SOX6. Human SOX5 is 763 amino acids (aa) in length and contains two coiled-coil regions (aa 193‑274 and 448‑515), plus one Q/glutamine (aa 234‑272) and one HMG box (aa 556‑624). HMG domains participate in DNA-binding and protein‑protein interaction. There are two alternate start sites at Met14 and Met417 (which creates a short/testis form), plus one variant with a three aa substitution for aa 389‑763, another variant with a two aa substitution for aa 1‑388, and a third variant with a one aa substitution for aa 534‑763. Over aa 417‑763, human SOX5 is 97% aa identical to mouse SOX5.
Secondary Antibodies |
Isotype Controls |
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