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SOX11 Antibody (SOX11/7236) [CoraFluor™ 1]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clone
SOX11/7236
Clonality
Monoclonal
Host
Mouse
Conjugate
CoraFluor 1

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP3-14182AF350
Alexa Fluor 405
NBP3-14182AF405
Alexa Fluor 488
NBP3-14182AF488
Alexa Fluor 532
NBP3-14182AF532
Alexa Fluor 594
NBP3-14182AF594
Alexa Fluor 647
NBP3-14182AF647
Alexa Fluor 700
NBP3-14182AF700
Alexa Fluor 750
NBP3-14182AF750
Allophycocyanin
NBP3-14182APC
Biotin
NBP3-14182B
DyLight 350
NBP3-14182UV
DyLight 405
NBP3-14182V
DyLight 488
NBP3-14182G
DyLight 550
NBP3-14182R
DyLight 594
NBP3-14182DL594
DyLight 650
NBP3-14182C
DyLight 680
NBP3-14182FR
DyLight 755
NBP3-14182IR
FITC
NBP3-14182F
HRP
NBP3-14182H
Janelia Fluor 525
NBP3-14182JF525
Janelia Fluor 549
NBP3-14182JF549
Janelia Fluor 585
NBP3-14182JF585
Janelia Fluor 635
NBP3-14182JF635
Janelia Fluor 646
NBP3-14182JF646
Janelia Fluor 669
NBP3-14182JF669
PE
NBP3-14182PE
PerCP
NBP3-14182PCP
Unconjugated
NBP3-13779-100ug
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP3-13779-100ug
Azide and BSA Free
NBP3-14182
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SOX11 Antibody (SOX11/7236) [CoraFluor™ 1] Summary

Description
CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
Immunogen
Recombinant fragment (around aa50-200) of human SOX11 protein (exact sequence is proprietary) (Uniprot: P35716 )
Localization
Nucleus
Marker
Mantle Cell Lymphoma Marker
Specificity
Recognizes a protein of ~47kDa, identified as SOX11. This monoclonal antibody is highly specific and does not cross-react with other members of the SOX-family. Mantle cell lymphoma (MCL) accounts for 5% to 10% of mature B-cell neoplasms and is an aggressive disease genetically characterized by overexpression of Cyclin D1. Cyclin D1 overexpression is the hallmark of MCL. However, approximately 5%-10% of MCLs lack Cyclin D1 expression and may be misdiagnosed. Almost all Cyclin D1-positive as well as Cyclin D1-negative MCL, show overexpression of SOX-11. The detection of this transcription factor is a useful biomarker for identifying true cyclin D1-negative MCL.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
SOX11
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
No Preservative
Purity
Protein A or G purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for SOX11 Antibody (SOX11/7236) [CoraFluor™ 1]

  • SOX11
  • SRY (sex determining region Y)-box 11
  • SRY (sex-determining region Y)-box 11
  • SRY-related HMG-box gene 11
  • transcription factor SOX-11

Background

SOX11 encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may function in the developing nervous system and play a role in tumorigenesis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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SOX11 Antibody
(SOX11/7236) [CoraFlu ...
NBP3-14182CL1
SOX11 Antibody (SOX11/7236) [CoraFluor™ 1]
Species: Hu
Applications: IHC

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Secondary Antibodies

 

Isotype Controls

Additional SOX11 Products

Blogs on SOX11.

Check out the latest blog posts on SOX11.
SOX-11 seals your fate
The SOX-11 transcription factor is a member of the SOX family known to be involved in embryonic development regulation and cell fate determination. The protein acts as a transcriptional regulator and appears to modulate fundamental aspects of normal e...  Read full blog post.
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Bioinformatics

Gene Symbol SOX11