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Serpin B6 Antibody [Unconjugated]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Sheep
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

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Catalog# & Conjugate Size Price
Biotin
BAF4336
View Available Formulations
Catalog# & Formulation Size Price
Carrier Free
AF4336-SP
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Serpin B6 Antibody [Unconjugated] Summary

Immunogen
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Serpin B6
Asp2-Pro376
Accession # P35237
Specificity
Detects human Serpin B6 in direct ELISAs and Western blots. In direct ELISAs, less than 5% cross‑reactivity with recombinant human (rh) Serpin B8 and rhSerpin B9 is observed.
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Sheep
Gene
SERPINB6
Purity Statement
Antigen Affinity-purified
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Applications/Dilutions

Dilutions
  • Western Blot 0.1 ug/mL
Publications
Read Publication using
AF4336 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Serpin B6 Antibody [Unconjugated]

  • CAP
  • CAPMGC111370
  • Cytoplasmic antiproteinase
  • deafness, autosomal recessive 91
  • DFNB91
  • Peptidase inhibitor 6
  • PI6
  • PI-6
  • PI6MSTP057
  • Placental thrombin inhibitor
  • protease inhibitor 6 (placental thrombin inhibitor)
  • PTI
  • PTIDKFZp686I04222
  • serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 6
  • Serpin B6
  • serpin peptidase inhibitor, clade B (ovalbumin), member 6
  • SPI3

Background

Serpin B6 (serine protease inhibitor-clade B#6; also placental thrombin inhibitor) is a 42 kDa, cytosolic member of the ovalbumin (clade B)-subfamily, Serpin superfamily of protease inhibitors. It is produced by multiple cell types (keratinocytes; monocytes; mast cells), and shows inhibitory activity towards thrombin, plasmin and chymotrypsin. Human Serpin B6 is 376 amino acids (aa) in length. An active inhibitor site lies between Glu327 and Met338. Multiple potential isoforms exist. One shows a 28 aa substitution for the N-terminal 191 amino acids. Three others have alternate start sites that vary from 14‑33 aa’s upstream of the standard start site. Human Serpin B6 shares 76% aa identity with mouse Serpin B6.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Serpin B6 Antibody (AF4336)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: Western Blot.


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Bioinformatics

Gene Symbol SERPINB6
Uniprot