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SCP3/SYCP3 Antibody (6F9C5) [Alexa Fluor® 488]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, Flow, ICC/IF, IHC
Clone
6F9C5
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 488

Order Details

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SCP3/SYCP3 Antibody (6F9C5) [Alexa Fluor® 488] Summary

Immunogen
Partial recombinant human SCP3 (between residues 1-200) expressed in E. coli [Uniprot: Q8IZU3]
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
SYCP3
Purity
Ammonium sulfate precipitation
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Ammonium sulfate precipitation

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for SCP3/SYCP3 Antibody (6F9C5) [Alexa Fluor® 488]

  • COR1
  • MGC71888
  • SCP3 chromosome 3 open reading frame 8
  • SCP3 COR1
  • SCP3
  • SCP-3
  • SYCP3
  • synaptonemal complex protein 3

Background

SCP3 is a major component of the transverse filaments of the synaptonemal complexes that mediate synapses during the zygotene stage. SCP-3 is formed between homologus chromosomes during meiotic prophase, and plays an essential role in the meiotic function of spermatogenesis. Therefore, this protein is necessary for proper testis development and defects in the SYCP3 gene can lead to azoospermia.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for SCP3/SYCP3 Antibody (NBP2-23487AF488) (0)

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Secondary Antibodies

 

Isotype Controls

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Research Areas for SCP3/SYCP3 Antibody (NBP2-23487AF488)

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Blogs on SCP3/SYCP3.

SCP3: A Key to Meiotic Recombination, Sterility and Cancer
Synaptonemal Complex Protein 3 (SCP3), which is a protein present in the synaptonemal complex which is responsible for pairing, synapsis, and recombination of homologous chromosomes during meiosis. Meiosis, in basic terms, is where germ cells divide t...  Read full blog post.

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Bioinformatics

Gene Symbol SYCP3