RelA/NFkB p65 Antibody

NF-kB (nuclear factor kB) regulates the expression of a large number of genes that play critical roles in apoptosis, viral replication, tumorigenesis, various autoimmune diseases and inflammation. The active nuclear form of the NF-kB transcription factor complex is composed of two DNA binding subunits, NF-kB p65 and p50, both of which share extensive N-terminal sequence homology with the v-rel oncogene product. N-terminal regions of p50 and p65 are critical for DNA binding and help determine the DNA-binding specificities of p50 and p65.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: IP, WB.

Showing Publications 1 - 2 of 2.

Publications using NB100-56502	Applications	Species
Bimonte S, Barbieri A, Palma G et al. Dissecting the role of curcumin in tumour growth and angiogenesis in mouse model of human breast cancer Biomed Res Int 2015-04-16 [PMID: 25879038] (WB, Human) Details: p65 antibody used for WB on lysates of ER-negative breast cancer cells MDA.MB231- xenografts from mice that were treated or not with curcumin (Figure 3C).	WB	Human
Milanovic M. Regulation of conformation and activity of nuclear NF-kappaBeta p65 by phosphorylation, chaperones and p65 DNA-binding. Thesis. 2014-03-03 (IP, Human) Details: Nuclear extracts of HEk-393 cells stimulated with TNF, Fig 3.8. The results showed that the p65 pAb antibody immunoprecipitated TNF-activated nuclear p65.	IP	Human

Array NB100-56502

• RelA/NFkB p65 Antibodies
• RelA/NFkB p65 Antibody Pack
• RelA/NFkB p65 ELISA Kits
• RelA/NFkB p65 Inhibitors
• RelA/NFkB p65 Kit
• RelA/NFkB p65 Lysate
• RelA/NFkB p65 Proteins