Western Blot: RECQ1 Antibody [NB100-618] - Detection of human and mouse RecQ1 by Western blot using NB100-618 and human RecQ1 by immunoprecipitation. RecQ1 was successfully immunoprecipitated by NB100-619.
Immunohistochemistry-Paraffin: RECQ1 Antibody [NB100-618] - Human skin basal cell carcinoma. Antibody: Affinity purified rabbit anti-RecQ1 used at a dilution of 1:200 (1ug/ml). detection: DAB
The immunogen recognized by this antibody maps to a region between residues 1 and 50 of human RecQ protein-like (DNA helicase Q1-like) 1 using the numbering given in Swiss-Prot entry P46063 (GeneID 5965).
Predicted Species
Orangutan (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
RECQL
Purity
Immunogen affinity purified
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The protein encoded by this gene is a member of the RecQ DNA helicase family. DNA helicases are enzymes involved in various types of DNA repair, including mismatch repair, nucleotide excision repair and direct repair. Some members of this family are associated with genetic disorders with predisposition to malignancy and chromosomal instability. The biological function of this helicase has not yet been determined. Two alternatively spliced transcripts, which encode the same isoform but differ in their 5' and 3' UTRs, have been described.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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