Recombinant Human IFN-alpha D (alpha 1 [Val 114]) Protein

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Interferon-alpha (IFN-alpha), also known as leukocyte interferon, represents a group of related but distinct proteins that share over 95% amino acid sequence homology. They are members of the type I interferon family which share a common cell surface receptor composed of two subunits, a 100 kDa ligand-binding subunit (IFN-alpha R2) and a 125 kDa ligand binding and signal transduction subunit (IFN-alpha R1) that is involved both in ligand binding and signal transduction. IFN-alpha has both anti-viral and immunomodulatory activities on target cells.

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 1 application: Bioassay.

Showing Publications 1 - 2 of 2.

Publications using 11125-1	Applications	Species
Wilson TR, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, Peng J, Lin E, Wang Y, Sosman J, Ribas A, Li J, Moffat J, Sutherlin DP, Koeppen H, Merchant M, Neve R, Settleman J Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature, 2012-07-26;487(7408):505-9. 2012-07-26 [PMID: 22763448] (Bioassay, Human)	Bioassay	Human
Wu TG, Rose WA, Albrecht TB, Knutson EP, Konig R, Perdigao JR, Nguyen AP, Fleischmann WR IFN-alpha-induced murine B16 melanoma cancer vaccine cells: induction and accumulation of cell-associated IL-15. J. Interferon Cytokine Res., 2007-01-01;27(1):13-22. 2007-01-01 [PMID: 17266439] (Bioassay, Mouse)	Bioassay	Mouse

Array 11125-1

• IFN-alpha D Proteins and Enzyme