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PTPN14/PTPD2 Antibody

Images

 
Orthogonal Strategies: Western Blot: PTPN14/PTPD2 Antibody [NBP2-38712] - Analysis in human cell lines U-251MG and MCF-7 using anti-PTPN14 antibody. Corresponding PTPN14 RNA-seq data are presented for the same ...read more
Immunocytochemistry/ Immunofluorescence: PTPN14/PTPD2 Antibody [NBP2-38712] - Staining of human cell line HeLa shows localization to nucleoplasm. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: PTPN14/PTPD2 Antibody [NBP2-38712] - Staining of human prostate shows weak cytoplasmic positivity in smooth muscle cells.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

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PTPN14/PTPD2 Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to amino acids: PMLREKMEYSAQLQAALARIPNKPPPEYPGPRKSVSNGALRQDQASLPPAMARARVLRHGPAKAISMSRTD
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PTPN14
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
PTPN14/PTPD2 Protein (NBP2-38712PEP)

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (82%), Rat (83%)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for PTPN14/PTPD2 Antibody

  • EC 3.1.3
  • EC 3.1.3.48
  • MGC126803
  • PEZ
  • PEZcytoskeletal-associated protein tyrosine phosphatase
  • protein tyrosine phosphatase, non-receptor type 14
  • Protein-tyrosine phosphatase pez
  • PTP36
  • PTPN14
  • tyrosine-protein phosphatase non-receptor type 14

Background

PTPD2 is a member of the protein tyrosine phosphatase (PTP) family. The PTPs have high substrate specificity for phosphotyrosyl proteins and, at the primary sequence level, share little similarity with the protein serine phosphatases, protein threonine phosphatases, or the acid and alkaline phosphatases. This PTP contains an N-terminal noncatalytic domain similar to that of band 4.1 superfamily cytoskeleton-associated proteins, which suggested the membrane or cytoskeleton localization of this protein. The specific function of this PTP has not yet been determined, although there is evidence to suggest that PTPD2 is involved in regulating cell proliferation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PTPN14
Uniprot