PTGER4/EP4 Antibody

Prostaglandin E receptor EP4 is a Prostanoid Receptor with a relaxing effect on smooth muscle. It may play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function. EP4 has been reported to be expressed in blood, colon, immune tissue, intestine, kidney, lung, ovary, skin, and uterus. ESTs have been isolated from a wide range of human tissue libraries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 3 applications: FLOW, ICC/IF, WB.

Showing Publications 1 - 3 of 3.

Publications using NLS3898	Applications	Species
Patterson A, Plett P, Sampson C et al. Prostaglandin E2 Enhances Aged Hematopoietic Stem Cell Function Stem Cell Rev Rep 2021-05-11 [PMID: 33974233]
Gobec M, Prijatelj M, Delic J et al. Chemo-sensitizing effects of EP4 receptor-induced inactivation of nuclear factor-kB. Eur J Pharmacol. 2014-09-09 [PMID: 25218986] (FLOW, ICC/IF, Human) Details: Prostaglandin E Receptor EP4 antibody used for ICC-IF and FLOW applications performed on RAMOS, MHH-PRE B, NALM-6, KOPN-8, MOLT-4, JURKAT, THP1, U937 and Human lymphoblastoid cell lines (LCLs). In ICC-IF, the cells were fixed in 4%PFA for 15 minutes RT, primary used at 10ug/ml concentration, goat anti-rabbit IgG conjugated with AlexaFluor 488 dye used at 0.4ug/ml (Immunostaining images shown in Figure 1C). For FLOW, the cells were fixed in 4% PFA, permeabilized with 0.5% Triton X solution, Incubated with primary 5ug/ml concentration, AlexaFluor 488 conjugated secondary followed by washing and detection on FACScalibur (Figure 1D).	FLOW, ICC/IF	Human
Prijatelj M, Celhar T, Mlinaric-Rascan I. Prostaglandin EP4 receptor enhances BCR-induced apoptosis of immature B cells. Prostaglandins Other Lipid Mediat. 2011-08-01 [PMID: 21600299] (WB, Mouse) Details: Prostaglandin E Receptor EP4. WB: Mouse B lymphoma (WEHI 231) cell line, Fig 4.	WB	Mouse

Array NLS3898

• PTGER4/EP4 Antibodies
• PTGER4/EP4 Proteins