Orthogonal Strategies: Immunohistochemistry-Paraffin: PP14/Glycodelin Antibody [NBP1-89782] - Analysis in human endometrium and prostate tissues. Corresponding PP14/Glycodelin RNA-seq data are presented for the ...read more
Independent Antibodies: Immunohistochemistry-Paraffin: PP14/Glycodelin Antibody [NBP1-89782] - Staining of human cerebral cortex, endometrium, prostate and testis using Anti-PP14/Glycodelin antibody NBP1-89782 ...read more
Western Blot: PP14/Glycodelin Antibody [NBP1-89782] - Analysis in human placenta tissue.
Immunohistochemistry-Paraffin: PP14/Glycodelin Antibody [NBP1-89782] - Staining of human testis shows no positivity in cells in seminiferous ducts as expected.
Immunohistochemistry-Paraffin: PP14/Glycodelin Antibody [NBP1-89782] - Staining of human cerebral cortex shows no positivity in neurons as expected.
Immunohistochemistry-Paraffin: PP14/Glycodelin Antibody [NBP1-89782] - Staining of human endometrium shows weak to moderate cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: PP14/Glycodelin Antibody [NBP1-89782] - Staining of human prostate shows no positivity in glandular cells as expected.
This antibody was developed against Recombinant Protein corresponding to amino acids: NYTVANEATLLDTDYDNFLFLCLQDTTTPIQSMMCQYLARVLVEDDEIMQGFIRAFRPLPRHLWYLLDLKQME
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PAEP
Purity
Immunogen affinity purified
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Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified
Alternate Names for PP14/Glycodelin Antibody
alpha uterine protein
GdF
GdS
Glycodelin
glycodelin-A
glycodelin-F
glycodelin-S
MGC138509
MGC142288
PAEP
PEP
Placental protein 14
PP14 protein (placental protein 14)
PP14
PP14GDPAEGGdA
pregnancy-associated endometrial a
Pregnancy-associated endometrial alpha-2 globulin
pregnancy-associated endometrial alpha-2-globulin
progestagen-associated endometrial protein (placental protein 14
progestagen-associated endometrial proteinPEG
Progesterone-associated endometrial protein
Background
PAEP (Progesterone-associated endometrial protein, glycodelin, PEG, PP14) is a glycoprotein belonging to lipocalin structural superfamily. It shares a sequence homology to beta-lactoglobulins containing a retinol-binding motif and it is mainly produced by secretory and decidualized endometrium in women and by seminal vesicle epithelium in men (1). PAEP function is not clearly understood. However, glycosylated version of PAEP (GdA) has been associated to contraceptive and immunosuppressive activities during reproduction. PAEP is the main protein produced by secretory endometrium during mid-luteal phase of the menstrual cycle and during the first semester of pregnancy. Therefore, PAEP has been linked as an ideal biomarker of endometrial activity and function for in vitro fertilization treated women (2).
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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