PP14/Glycodelin Products

Description

PAEP (Progesterone-associated endometrial protein, glycodelin, PEG, PP14) is a glycoprotein belonging to lipocalin structural superfamily. It shares a sequence homology to beta-lactoglobulins containing a retinol-binding motif and it is mainly produced by secretory and decidualized endometrium in women and by seminal vesicle epithelium in men (1). PAEP function is not clearly understood. However, glycosylated version of PAEP (GdA) has been associated to contraceptive and immunosuppressive activities during reproduction. PAEP is the main protein produced by secretory endometrium during mid-luteal phase of the menstrual cycle and during the first semester of pregnancy. Therefore, PAEP has been linked as an ideal biomarker of endometrial activity and function for in vitro fertilization treated women (2).

Bioinformatics

Entrez	5047 Human
Uniprot	NM_001018049 Human NM_002571 Human NP_002562 Human NP_002562.2 Human
Product By Gene ID	5047
Alternate Names	alpha uterine protein GdF GdS glycodelin glycodelin-A glycodelin-F glycodelin-S MGC138509 MGC142288 PEP Placental protein 14 PP14 protein (placental protein 14) PP14GDPAEGGdA pregnancy-associated endometrial a Pregnancy-associated endometrial alpha-2 globulin pregnancy-associated endometrial alpha-2-globulin progestagen-associated endometrial protein (placental protein 14 progestagen-associated endometrial proteinPEG Progesterone-associated endometrial protein