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PKA C alpha Antibody (6D2.1) [Janelia Fluor® 646]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clone
6D2.1
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 646

Order Details

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PKA C alpha Antibody (6D2.1) [Janelia Fluor® 646] Summary

Immunogen
Peptide corresponding to amino acids ESPAQNTAHLDQFERIK of human proteinkinase A c alpha (PKAc alpha).
Specificity
The antibody C-50 reacts with Cytokeratin peptides 5 and 18 (58 and 45 kDa). Cytokeratins are a member of intermediate filaments subfamily represented in epithelial tissues.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
PRKACA
Purity
Protein A purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for PKA C alpha Antibody (6D2.1) [Janelia Fluor® 646]

  • cAMP-dependent protein kinase catalytic subunit alpha
  • Cs
  • EC 2.7.11
  • EC 2.7.11.11
  • MGC102831
  • MGC48865
  • PKA C alpha
  • PKA C-alpha
  • Pkaca
  • PKCA1
  • PKCD
  • PRKACA
  • protein kinase A catalytic subunit
  • protein kinase, cAMP-dependent, catalytic, alpha

Background

PKA (Protein Kinase A), also known as cAMP-dependent protein kinase, phosphorylates serine or threonine residues in target protein in response to elevated levels of cAMP. Inactive PKA exists as a tetrameric protein composed of two regulatory (R) subunits and two catalytic (C) subunits. Activation occurs when two cAMP molecules bind to each R subunit which causes a conformational change that releases the active C subunits.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol PRKACA