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Pentraxin 3/TSG-14 Antibody (SR1716)

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Western Blot: Pentraxin 3/TSG-14 Antibody (SR1716) [NBP3-21983] - Western blot analysis using NBP3-21983 in HUVEC cell lysate.
Western Blot: Pentraxin 3/TSG-14 Antibody (SR1716) [NBP3-21983] - Western blot analysis using NBP3-21983 in HUVEC cell lysate.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, Flow
Clone
SR1716
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

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Pentraxin 3/TSG-14 Antibody (SR1716) Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
A synthesized peptide derived from human Pentraxin 3/TSG-14 (Uniprot #: P26022)
Specificity
Detects endogenous levels of total Pentraxin 3/TSG-14
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
PTX3
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry 1:50
  • Western Blot 1:500-1:2000
Theoretical MW
42 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, pH 7.4, 150mM NaCl, 50% glycerol.
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for Pentraxin 3/TSG-14 Antibody (SR1716)

  • alpha-induced protein 5
  • pentaxin-related gene, rapidly induced by IL-1 beta, tumor necrosis factor
  • Pentaxin-related protein PTX3
  • Pentraxin 3
  • pentraxin 3, long
  • pentraxin-3
  • pentraxin-related gene, rapidly induced by IL-1 beta
  • pentraxin-related protein PTX3
  • PTX3
  • TNF alpha-induced protein 5
  • TNFAIP5
  • TSG14
  • TSG-14
  • TSG-14pentaxin-related gene, rapidly induced by IL-1 beta
  • Tumor necrosis factor alpha-induced protein 5
  • tumor necrosis factor, alpha-induced protein 5
  • Tumor necrosis factor-inducible gene 14 protein
  • tumor necrosis factor-inducible protein TSG-14

Background

Pentraxin 3 (PTX3) is the prototypic member of the long pentraxin family sharing the C-terminal domain with short pentraxins (C-reactive protein and serum amyloid P component) and containing a unique N-terminal domain. The protein is a soluble pattern recognition receptor and represents a nonredundant component of the humoral innate immunity against selected pathogens. PTX3 is rapidly produced and released at inflammatory sites by diverse cell types including monocytes/macrophages, endothelial cells, vascular smooth muscle cells, fibroblasts, and adipocytes. It interacts with several ligands, including growth factors, extracellular matrix components and selected pathogens. PTX3 has been implicated in vascular damage, angiogenesis, atherosclerosis, and restenosis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PTX3