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NFkB1/NFkB p105 Antibody [PE]

 
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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, Simple Western, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
PE

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP1-77395AF350
Alexa Fluor 405
NBP1-77395AF405
Alexa Fluor 488
NBP1-77395AF488
Alexa Fluor 532
NBP1-77395AF532
Alexa Fluor 594
NBP1-77395AF594
Alexa Fluor 647
NBP1-77395AF647
Alexa Fluor 700
NBP1-77395AF700
Alexa Fluor 750
NBP1-77395AF750
Allophycocyanin
NBP1-77395APC
Biotin
NBP1-77395B
CoraFluor 1
NBP1-77395CL1
DyLight 350
NBP1-77395UV
DyLight 405
NBP1-77395V
DyLight 488
NBP1-77395G
DyLight 550
NBP1-77395R
DyLight 594
NBP1-77395DL594
DyLight 650
NBP1-77395C
DyLight 680
NBP1-77395FR
DyLight 755
NBP1-77395IR
FITC
NBP1-77395F
HRP
NBP1-77395H
Janelia Fluor 525
NBP1-77395JF525
Janelia Fluor 549
NBP1-77395JF549
Janelia Fluor 585
NBP1-77395JF585
Janelia Fluor 635
NBP1-77395JF635
Janelia Fluor 646
NBP1-77395JF646
Janelia Fluor 669
NBP1-77395JF669
PerCP
NBP1-77395PCP
Unconjugated
NBP1-77395
mFluor Violet 450 SE
NBP1-77395MFV450
mFluor Violet 500 SE
NBP1-77395MFV500
mFluor Violet 610 SE
NBP1-77395MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP1-77395
BSA Free
NBP1-77395SS
BSA Free
NBP1-77395
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NFkB1/NFkB p105 Antibody [PE] Summary

Immunogen
A genomic peptide made to an N-terminal region of the human NFkB p105/p50 protein (within residues 400-590). [Swiss-Prot P19838]
Localization
Nucleus and cytoplasm. Nuclear, but also found in the cytoplasm in an inactive form complexed to an inhibitor (I-kappa-B).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
NFKB1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • Simple Western
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for NFkB1/NFkB p105 Antibody [PE]

  • DNA-binding factor KBF1
  • EBP-1
  • NF-kappa-B
  • NFkB1
  • NF-kB1
  • NFKB-p105
  • Nuclear factor NF-kappa-B p105 subunit
  • Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
  • p105

Background

Nuclear factor kappa beta (NFKB) is a transcription factor that is highly influenced by stress, free-radicals, UV light and hypoxia. Unsurprisingly, NFKB is essential for many human cancers, as it regulates the expression of many downstream proteins that regulate or modify cellular growth and development. NFKB effects on angiogenic pathways and reactive mechanisms to stress and damage are well established throughout literature. Atherosclerosis is partly attributed to the mis-regulation of NFKB in hypoxia. Arthritis is related to inflammation proteins regulated through NFKB. It also has been shown to be important in synapses in brain, leading to memory and cognitive ability or impairment. In all, NFKB is one of the fastest responding transcription factors in humans, and is likely to mediate many responsive events in diseases and injury recovery.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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NFkB1/NFkB p105
Antibody [PE]
NBP1-77395PE
NFkB1/NFkB p105 Antibody [PE]
Species: Hu, Mu
Applications: WB, Simple Western, ICC/IF, IHC

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Bioinformatics

Gene Symbol NFKB1