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NEK1 Antibody [DyLight 488]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, IP (-)
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 488

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NEK1 Antibody [DyLight 488] Summary

Immunogen
The immunogen recognized by the antibody maps to a region between residue 1208 to 1258 of human Never in Mitosis A-Related Kinase 1 using the numbering given in entry NP_036356.1.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
NEK1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for NEK1 Antibody [DyLight 488]

  • DKFZp686D06121
  • DKFZp686K12169
  • EC 2.7.11
  • EC 2.7.11.1
  • KIAA1901MGC138800
  • Never in mitosis A-related kinase 1
  • NIMA (never in mitosis gene a)-related kinase 1
  • NimA-related protein kinase 1
  • NY-REN-55
  • protein-serine/threonine kinase
  • Renal carcinoma antigen NY-REN-55
  • serine/threonine-protein kinase Nek1
  • SRPS2

Background

Belonging to the NEK Ser/Thr protein kinase family, NEK1 plays an important role in the cell by responding to DNA damage. Molecular functions for NEK1 include protein serine/threonine kinase activity, protein tyrosine kinase activity, protein binding and ATP binding. More specifically, NEK1 is involved in cell cycle regulation, and the protein encoded by this gene is a serine/threonine kinase which is found in a centrosomal complex with FEZ1. Additionally, NEK1 also appears to possess tyrosine kinase activity and is involved in the control of meiosis and cilium assembly. NEK1 is known to interact with FEZ1, FEZ2, KIF3A, TSC2 and MRE11A. Common diseases for NEK1 include adenocarcinoma, cancer, short rib-polydactyly syndrome II and epithelial neoplasia.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

Additional NEK1 Products

Array NBP2-36534G

Research Areas for NEK1 Antibody (NBP2-36534G)

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Bioinformatics

Gene Symbol NEK1