NEK1 Products

Description

Belonging to the NEK Ser/Thr protein kinase family, NEK1 plays an important role in the cell by responding to DNA damage. Molecular functions for NEK1 include protein serine/threonine kinase activity, protein tyrosine kinase activity, protein binding and ATP binding. More specifically, NEK1 is involved in cell cycle regulation, and the protein encoded by this gene is a serine/threonine kinase which is found in a centrosomal complex with FEZ1. Additionally, NEK1 also appears to possess tyrosine kinase activity and is involved in the control of meiosis and cilium assembly. NEK1 is known to interact with FEZ1, FEZ2, KIF3A, TSC2 and MRE11A. Common diseases for NEK1 include adenocarcinoma, cancer, short rib-polydactyly syndrome II and epithelial neoplasia.

Bioinformatics

Uniprot	NEK1_HUMAN Human NP_036356 Human
Product By Gene ID	4750
Alternate Names	DKFZp686D06121 DKFZp686K12169 EC 2.7.11 EC 2.7.11.1 KIAA1901MGC138800 Never in mitosis A-related kinase 1 NIMA (never in mitosis gene a)-related kinase 1 NimA-related protein kinase 1 NY-REN-55 protein-serine/threonine kinase Renal carcinoma antigen NY-REN-55 serine/threonine-protein kinase Nek1 SRPS2

Research Areas for NEK1

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication