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NECAB3 Antibody

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Immunohistochemistry: NECAB3 Antibody [NBP2-68902] - Immunohistochemical staining of human cerebral cortex shows strong cytoplasmic positivity in neuronal cells.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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NECAB3 Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to amino acids: SSEAEMQWRLQVNRLQELIDQLECKVRAVGPGPHKGGPSWYPPEPGPCWRPGPHSVPSQAPRLEPLREEDLAK
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
NECAB3
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
Application Notes
Recommended conditions for IHC,Retrieval method: HIER pH6
Control Peptide
NECAB3 Recombinant Protein Antigen (NBP2-68902PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Protein A purified

Alternate Names for NECAB3 Antibody

  • Amyloid beta A4 protein-binding family A member 2-binding protein
  • APBA2BPfamily A, member 2 binding protein
  • dJ63M2.4
  • dJ63M2.5
  • EFCBP3STIP3
  • EF-hand calcium binding protein 3
  • Neuronal calcium-binding protein 3
  • neuronal calcium-binding protein NECAB3
  • NIP1Nek2-interacting protein 1
  • N-terminal EF-hand calcium binding protein 3
  • N-terminal EF-hand calcium-binding protein 3
  • synaptotagmin interacting protein 2
  • synaptotagmin interacting protein STIP3
  • SYTIP2
  • XB51X11L-binding protein 51

Background

NECAB3 is encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol NECAB3