NECAB3 Products

Description

NECAB3 is encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Bioinformatics

Uniprot	AAH47673.1 Human NM_031231 Human Q96P71 Human
Product By Gene ID	63941
Alternate Names	Amyloid beta A4 protein-binding family A member 2-binding protein APBA2BPfamily A, member 2 binding protein dJ63M2.4 dJ63M2.5 EFCBP3STIP3 EF-hand calcium binding protein 3 Neuronal calcium-binding protein 3 neuronal calcium-binding protein NECAB3 NIP1Nek2-interacting protein 1 N-terminal EF-hand calcium binding protein 3 N-terminal EF-hand calcium-binding protein 3 synaptotagmin interacting protein 2 synaptotagmin interacting protein STIP3 SYTIP2 XB51X11L-binding protein 51

Research Areas for NECAB3

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Lipid and Metabolism