Myoferlin Antibody

Myoferlin belongs to the ferlin family and contains five C2 domains. It is a calcium/phospholipid binding protein that plays a role in the plasmalemma repair mechanism of endothelial cells that permits rapid resealing of membranes disrupted by mechanical stress. It is also involved in endocytic recycling and implicated in VEGF signal transduction by regulating the levels of the receptor KDR. Myoferlin is expressed in myoblast and endothelial cells (at protein level), highly expressed in cardiac and skeletal muscles, also present in lung and at very low levels in kidney, placenta and brain. There are eight named isoforms.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Showing Publications 1 - 3 of 3.

Publications using NBP1-84694	Applications	Species
Becker J, Schleinitz A, Hermsen C et al. Rab GTPase-regulated phagosome-lysosome fusion is bypassed by micromolar calcium Journal of cell science 2023-04-19 [PMID: 37073598]
Volakis LI, Li R, Ackerman WE IV et al. Loss of Myoferlin Redirects Breast Cancer Cell Motility towards Collective Migration. PLoS One 2014-01-01 [PMID: 24586247]
Lindgren D, Bostrom AK, Nilsson K et al. Isolation and characterization of progenitor-like cells from human renal proximal tubules. Am J Pathol 2011-02-01 [PMID: 21281815]

Array NBP1-84694

• Myoferlin Antibodies
• Myoferlin Proteins