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MST4 Antibody

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Western Blot: MST4 Antibody [NB100-1584] - Detection of Human MST4(MASK) on HeLa whole cell lysate using NB100-1584. MST4(MASK) was immunoprecipitated using rabbit anti-MST4(MASK) antibody NB100-1583.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.2 mg/ml

Order Details

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MST4 Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 375 and the C-terminus (residue 416) of human Mammalian Ste20-like Kinase 4 (Mst3 and SOK1-related kinase) using the numbering given in entry NP_057626.2 (GeneID 51765).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
STK26
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunoprecipitation
  • Western Blot 1:1000-1:10000

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
TBS and 0.1% BSA
Preservative
0.09% Sodium Azide
Concentration
0.2 mg/ml
Purity
Immunogen affinity purified

Alternate Names for MST4 Antibody

  • EC 2.7.11
  • EC 2.7.11.1
  • Mammalian STE20-like protein kinase 4
  • mammalian sterile 20-like 4
  • MASK
  • Mst3 and SOK1-related kinase
  • MST-4
  • serine/threonine protein kinase MASK
  • serine/threonine protein kinase MST4
  • Serine/threonine-protein kinase MASK
  • serine/threonine-protein kinase MST4
  • STE20-like kinase MST4

Background

MST4/STK24 is a member of the sterile 20 (Ste20)-like kinase family that acts upstream of mitogen-activated protein kinase (MAPK) pathways and regulates c-Jun N-terminal kinase (JNK), p38 and extracellular signal-regulated kinase (ERK). Ste20-like kinases are involved in a variety of cellular processes which include gene transcription, stress responses, cytoskeletal organization and apoptosis. In response to apoptotic signals, MST4/MASK is cleaved by caspase-3 and mediates apoptosis. MST4/MASK has been shown to influence cell growth and transformation by modulating ERK (extracellular signal-regulated kinase) signaling and may play a role in prostrate cancer. MST4/MASK may also play a role in cell motility. Alternate names for MST4/MASK include serine-threonine-protein kinase MST4, STE20-like kinase MST4, MST-4, mammalian STE20-like protein kinase 4, serine/threonine-protein kinase MASK, and mst3 and SOK1-related kinase.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol STK26
Entrez
Uniprot