Mouse Chemerin Quantikine ELISA Kit

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Chemerin, also known as Tazarotene-induced Gene 2, (Tig-2), is a member of the Cystatin superfamily. Chemerin is synthesized as a 163 aa precursor that contains a hydrophobic 20 aa N-terminal sequence, an intervening 137 aa Cystatin fold-containing domain, and a six aa C-terminal prosegment. It is activated by proteases of the coagulation, fibrinolytic, and inflammatory cascades. Chemerin is a chemoattractant for cells bearing the Chem R23 receptor, including plasmacytoid dendritic cells and tissue macrophages.

We have publications tested in 1 confirmed species: Mouse.

Showing Publications 1 - 10 of 10.

Publications using MCHM00	Applications	Species
L Zhao, Y Yamaguchi, WJ Shen, J Morser, LLK Leung Dynamic and tissue-specific proteolytic processing of chemerin in obese mice PLoS ONE, 2018-08-30;13(8):e0202780. 2018-08-30 [PMID: 30161155] (Mouse)		Mouse
Targeting VEGF-A in myeloid cells enhances natural killer cell responses to chemotherapy and ameliorates cachexia Nat Commun, 2016-08-19;7(0):12528. 2016-08-19 [PMID: 27538380] (Mouse)		Mouse
Gonzalvo-Feo S, Del Prete A, Pruenster M, Salvi V, Wang L, Sironi M, Bierschenk S, Sperandio M, Vecchi A, Sozzani S Endothelial cell-derived chemerin promotes dendritic cell transmigration. J Immunol, 2014-01-27;192(5):2366-73. 2014-01-27 [PMID: 24470498] (Mouse)		Mouse
The chemoattractant chemerin suppresses melanoma by recruiting natural killer cell antitumor defenses. J. Exp. Med., 2012-07-02;209(8):1427-35. 2012-07-02 [PMID: 22753924] (Mouse)		Mouse
Monnier J, Lewen S, O'Hara E, Huang K, Tu H, Butcher EC, Zabel BA Expression, Regulation, and Function of Atypical Chemerin Receptor CCRL2 on Endothelial Cells. J. Immunol., 2012-06-13;189(2):956-67. 2012-06-13 [PMID: 22696441] (Mouse)		Mouse
Ernst MC, Haidl ID, Zúñiga LA, Dranse HJ, Rourke JL, Zabel BA, Butcher EC, Sinal CJ Disruption of the chemokine-like receptor-1 (CMKLR1) gene is associated with reduced adiposity and glucose intolerance. Endocrinology, 2011-12-20;153(2):672-82. 2011-12-20 [PMID: 22186410] (Mouse)		Mouse
Bondue B, Vosters O, de Nadai P, Glineur S, De Henau O, Luangsay S, Van Gool F, Communi D, De Vuyst P, Desmecht D, Parmentier M ChemR23 dampens lung inflammation and enhances anti-viral immunity in a mouse model of acute viral pneumonia. PLoS Pathog., 2011-11-03;7(11):e1002358. 2011-11-03 [PMID: 22072972] (Mouse)		Mouse
Demoor T, Bracke KR, Dupont LL The Role of ChemR23 in the Induction and Resolution of Cigarette Smoke-Induced Inflammation. J. Immunol., 2011-03-23;186(9):5457-67. 2011-03-23 [PMID: 21430224] (Mouse)		Mouse
Bauer S, Wanninger J, Schmidhofer S, Weigert J, Neumeier M, Dorn C, Hellerbrand C, Zimara N, Schaffler A, Aslanidis C, Buechler C Sterol regulatory element-binding protein 2 (SREBP2) activation after excess triglyceride storage induces chemerin in hypertrophic adipocytes. Endocrinology, 2010-11-17;152(1):26-35. 2010-11-17 [PMID: 21084441] (Mouse)		Mouse
Becker M, Rabe K, Lebherz C, Zugwurst J, Goke B, Parhofer KG, Lehrke M, Broedl UC Expression of human chemerin induces insulin resistance in the skeletal muscle but does not affect weight, lipid levels, and atherosclerosis in LDL receptor knockout mice on high-fat diet. Diabetes, 2010-08-19;59(11):2898-903. 2010-08-19 [PMID: 20724582] (Mouse)		Mouse

Array MCHM00

• Chemerin Antibodies
• Chemerin ELISA Kits
• Chemerin Lysate
• Chemerin Protein
• Chemerin ELISAs
• Chemerin Proteins and Enzymes