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ChemR23/CMKLR1 Antibody (84939) [Unconjugated]

 (8 Publications)
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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
84939
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB362U-100UG
Alexa Fluor 405
FAB362V-100UG
Alexa Fluor 488
FAB362G-100UG
Alexa Fluor 532
FAB362X
Alexa Fluor 594
FAB362T-100UG
Alexa Fluor 647
FAB362R-100UG
Alexa Fluor 700
FAB362N-100UG
Alexa Fluor 750
FAB362S-100UG
Allophycocyanin
FAB362A
Allophycocyanin/Cy7
FAB362APCCY7
Biotin
FAB362B
DyLight 350
FAB362D
DyLight 405
FAB362E
DyLight 488
FAB362K
DyLight 550
FAB362L
DyLight 594
FAB362M
DyLight 650
FAB362W
DyLight 680
FAB362Y
DyLight 755
FAB362Z
FITC
FAB362F
HRP
FAB362H
Janelia Fluor 525
FAB362JF525
Janelia Fluor 549
FAB362I
Janelia Fluor 635
FAB362JF635
Janelia Fluor 646
FAB362J
Janelia Fluor 669
FAB362JF669
PE/Atto594
FAB362PEATT594
PE/Cy5.5
FAB362PECY55
PE/Cy7
FAB362PECY7
Phycoerythrin
FAB362P
View Available Formulations
Catalog# & Formulation Size Price
Carrier Free
FAB362P
Carrier Free
FAB362A
Carrier Free
MAB362-SP
Carrier Free
FAB362V-100UG
Carrier Free
FAB362U-100UG
Carrier Free
FAB362T-100UG
Carrier Free
FAB362S-100UG
Carrier Free
FAB362R-100UG
Carrier Free
FAB362N-100UG
Carrier Free
FAB362G-100UG
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ChemR23/CMKLR1 Antibody (84939) [Unconjugated] Summary

Immunogen
NS0 mouse myeloma cell line transfected with human ChemR23
Met1-Leu371
Accession # NP_004063
Specificity
Detects human ChemR23. Stains human ChemR23-transfected cells but not irrelevant transfectants.
Source
N/A
Isotype
IgG3
Clonality
Monoclonal
Host
Mouse
Gene
CMKLR1
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry 2.5 ug/10^6 cells
Publications
Read Publications using
MAB362 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for ChemR23/CMKLR1 Antibody (84939) [Unconjugated]

  • CHEMERINR
  • chemokine receptor-like 1
  • chemokine-like receptor 1
  • ChemR23
  • cmklr1
  • Dez
  • Gpcr27
  • G-protein coupled receptor ChemR23
  • G-protein coupled receptor DEZ
  • MGC126105
  • MGC126106
  • orphan G-protein coupled receptor, Dez

Background

ChemR23 is a chemoattractant receptor expressed on dendritic cells and activated macrophages. ChemR23 binds Chemerin and functions as a coreceptor for SIV and some primary HIV-1 strains.
  1. Samson, M. et al. (1998) Eur. J. Immunol. 28:1689.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for ChemR23/CMKLR1 Antibody (MAB362)(8)

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 2 applications: Flow Cytometry, ICC.


Filter By Application
Flow Cytometry
(5)
ICC
(1)
All Applications
Filter By Species
Human
(4)
Mouse
(1)
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Showing Publications 1 - 8 of 8.
Publications using MAB362 Applications Species
Herova M, Schmid M, Gemperle C, Hersberger M ChemR23, the receptor for chemerin and resolvin E1, is expressed and functional on M1 but not on M2 macrophages. J Immunol, 2015-01-30;194(5):2330-7. 2015-01-30 [PMID: 25637017] (Flow Cytometry, Human) Flow Cytometry Human
Zhou J, Liao D, Zhang S, Cheng N, He H, Ye R Chemerin C9 peptide induces receptor internalization through a clathrin-independent pathway. Acta Pharmacol Sin, 2014-03-24;35(5):653-63. 2014-03-24 [PMID: 24658352] (Flow Cytometry, Human) Flow Cytometry Human
Jenna L Cash, Stefania Bena, Sarah E Headland, Simon McArthur, Vincenzo Brancaleone, Mauro Perretti Chemerin15 inhibits neutrophil‐mediated vascular inflammation and myocardial ischemia‐reperfusion injury through ChemR23 EMBO reports 11/1/2013 [PMID: 23999103]
Cédric de Poorter, Kevin Baertsoen, Vincent Lannoy, Marc Parmentier, Jean-Yves Springael Consequences of ChemR23 Heteromerization with the Chemokine Receptors CXCR4 and CCR7 PLoS ONE 2/28/2013 [PMID: 23469143]
Gao L, Faibish D, Fredman G, Herrera B, Chiang N, Serhan C, Van Dyke T, Gyurko R Resolvin E1 and chemokine-like receptor 1 mediate bone preservation. J Immunol, 2012-12-14;190(2):689-94. 2012-12-14 [PMID: 23241890] (Flow Cytometry, ICC, Mouse) Flow Cytometry, ICC Mouse
Vivian Berg, Baldur Sveinbjörnsson, Signy Bendiksen, Jan Brox, Khaled Meknas, Yngve Figenschau Human articular chondrocytes express ChemR23 and chemerin; ChemR23 promotes inflammatory signalling upon binding the ligand chemerin(21-157) Arthritis Research & Therapy 12/30/2010 [PMID: 21192818]
Skrzeczynska-Moncznik J, Wawro K, Stefanska A, Oleszycka E, Kulig P, Zabel BA, Sulkowski M, Kapinska-Mrowiecka M, Czubak-Macugowska M, Butcher EC, Cichy J Potential role of chemerin in recruitment of plasmacytoid dendritic cells to diseased skin. Biochem. Biophys. Res. Commun., 2009-01-23;380(2):323-7. 2009-01-23 [PMID: 19168032] (Flow Cytometry, Human) Flow Cytometry Human
Martensson UE, Fenyo EM, Olde B, Owman C Characterization of the human chemerin receptor--ChemR23/CMKLR1--as co-receptor for human and simian immunodeficiency virus infection, and identification of virus-binding receptor domains. Virology, 2006-08-10;355(1):6-17. 2006-08-10 [PMID: 16904155] (Flow Cytometry, Human) Flow Cytometry Human

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Bioinformatics

Gene Symbol CMKLR1
Uniprot