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Ly-6G/Ly-6C Antibody (NIMP-R14) [FITC]

 (8 Publications)
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Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow, Func, ICC/IF, IHC
Clone
NIMP-R14
Clonality
Monoclonal
Host
Rat
Conjugate
FITC
Concentration
0.1 mg/ml

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Unconjugated
NB600-1387
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Ly-6G/Ly-6C Antibody (NIMP-R14) [FITC] Summary

Immunogen
Purified BALB/c mouse neutrophils
Epitope
This antibody recognizes a currently undetermined structure on the Neutrophil membrane
Specificity
This monoclonal antibody is highly specific for murine Ly-6G and Ly-6C.
Isotype
IgG2b
Clonality
Monoclonal
Host
Rat
Gene
Ly6g
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Functional
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
Publications
Read Publications using NBP1-60139.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
1 ml (100 ug/ml) 0.2 um filtered FITC conjugated antibody solution in PBS and 1.0% BSA
Preservative
0.02% Sodium Azide
Concentration
0.1 mg/ml
Purity
Protein G purified

Alternate Names for Ly-6G/Ly-6C Antibody (NIMP-R14) [FITC]

  • GR
  • Gr1
  • Gr-1
  • Ly-6
  • Ly6G
  • Ly-6G

Background

Ly6G is a GPI-anchored protein, that is also known as the myeloid differentiation antigen Gr1. The antigen is transiently expressed on monocytes in the bone marrow. The level of antigen expression in the bone marrow directly correlates with granulocyte differentiation and maturation. Ly6G is expressed predominantly on neutrophils, also in a subset of eosinophils, differentiating pre-monocytes, and plasmacytoid dendritic cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Ly-6G/Ly-6C Antibody (NBP1-60139)(8)


Showing Publications 1 - 8 of 8.
Publications using NBP1-60139 Applications Species
Navarini AA, Lang KS, Verschoor A et al. Innate immune-induced depletion of bone marrow neutrophils aggravates systemic bacterial infections Proc Natl Acad Sci USA [PMID: 19351895]

Details:
Used the FITC form of this antibody.
Nagendra S, Schlueter AJ. Absence of cross-reactivity between murine Ly-6C and Ly-6G Cytometry A 2004-04-01 [PMID: 15057973]

Details:
This citation used the FITC version of this antibody.
de Vries B, Kohl J, Leclercq WK, Wolfs TG, van Bijnen AA, Heeringa P, Buurman WA. Complement factor C5a mediates renal ischemia-reperfusion injury independent from neutrophils. J Immunol;170(7):3883-9. 2003-04-01 [PMID: 12646657]
Tacchini-Cottier F, Zweifel C, Belkaid Y. An immunomodulatory function for neutrophils during the induction of a CD4+ Th2 response in BALB/c mice infected with Leishmania major J Immunol [PMID: 10946291]

Details:
Used the FITC form of this antibody.
Lubberts E, Joosten LA, van Den Bersselaar L. Adenoviral vector-mediated overexpression of IL-4 in the knee joint of mice with collagen-induced arthritis prevents cartilage destruction J Immunol [PMID: 10510398]

Details:
Used the FITC form of this antibody.
Van Lent PL, Blom A, Holthuysen AE et al. Monocytes/macrophages rather than PMN are involved in early cartilage degradation in cationic immune complex arthritis in mice J Leukoc Biol [PMID: 9060449]

Details:
Used the FITC form of this antibody.
Lopez AF, Strath M, Sanderson CJ. Differentiation antigens on mouse eosinophils and neutrophils identified by monoclonal antibodies Br J Haematol 1984-07-01 [PMID: 6743568]

Details:
This citation used the FITC version of this antibody.
McLaren DJ, Strath M, Smithers SR. Schistosoma mansoni: evidence that immunity in vaccinated and chronically infected CBA/Ca mice is sensitive to treatment with a monoclonal antibody that depletes cutaneous effector cells Parasite Immunol [PMID: 3124065]

Details:
Used the FITC form of this antibody.

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ICC/IF Video Protocol

FAQs for Ly-6G/Ly-6C Antibody (NBP1-60139) (0)

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Secondary Antibodies

 

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Additional Ly-6G/Ly-6C Products

Array NBP1-60139

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Bioinformatics

Gene Symbol Ly6g