I want to know whether the LY-6G6C Antibody(NIMP-R14) has alternate name,such as "Gr 1"

Name: Ly-6G/Ly-6C Antibody (NIMP-R14)
Brand: Novus Biologicals
SKU: NB600-1387
Price: 339 USD

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Our Ly-6G6C antibody with catalogue number NB600-1387 was raised against purified BALB/c mouse neutrophils, and is highly specific for murine Ly-6G and Ly-6C. The Ly-6G/-6C locus encodes a family of Ly-6 proteins which includes Ly-6G and Ly-6C. Ly-6 antigens have a molecular weight of between 15,000 and 18,000. Ly6G is together with Ly6C a component of the myeloid differentiation antigen Gr-1.

At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Reactivity	MuSpecies Glossary
Applications	ELISA, Flow, Func, ICC/IF, IHC
Clone	NIMP-R14
Clonality	Monoclonal
Host	Rat
Conjugate	Unconjugated
Concentration	0.1 mg/ml

Catalog# & Conjugate	Size	Price
FITC NBP1-60139-0.05mg

Conjugate	Catalog #	Availability	Size	Price
FITC	NBP1-60139-0.05mg

Immunogen	Purified BALB/c mouse neutrophils
Epitope	This antibody recognizes a currently undetermined structure on the Neutrophil membrane
Specificity	This monoclonal antibody is highly specific for murine Ly-6G and Ly-6C.
Isotype	IgG2b
Clonality	Monoclonal
Host	Rat
Gene	Ly6g
Purity	Protein G purified
Innovator's Reward	Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward

Ly-6G/Ly-6C Antibody (NIMP-R14)

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Publications for Ly-6G/Ly-6C Antibody (NB600-1387)(21)

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Storage	Store at 4C.
Buffer	PBS containing 0.1% BSA
Preservative	No Preservative
Concentration	0.1 mg/ml
Purity	Protein G purified

Publications using NB600-1387	Applications	Species
Selim Chaib, José Alberto López-Domínguez, Marta Lalinde-Gutiérrez, Neus Prats, Ines Marin, Olga Boix, Andrea García-Garijo, Kathleen Meyer, María Isabel Muñoz, Mònica Aguilera, Lidia Mateo, Camille Stephan-Otto Attolini, Susana Llanos, Sandra Pérez-Ramos, Marta Escorihuela, Fatima Al-Shahrour, Timothy P. Cash, Tamara Tchkonia, James L. Kirkland, María Abad, Alena Gros, Joaquín Arribas, Manuel Serrano The efficacy of chemotherapy is limited by intratumoral senescent cells expressing PD-L2 Nature Cancer 2024-01-24 [PMID: 38267628]
Anton PE, Rutt LN, Capper C et al. Profiling the oxylipidome in aged mice after chronic ethanol feeding: Identifying lipid metabolites as drivers of hepatocyte stress Alcohol 2023-03-01 [PMID: 36150611] (Immunohistochemistry)	Immunohistochemistry
Khazaie K, Osman A, Yan B, et al. TCF1 controls Treg functions that regulate inflammation, CD8 T-cell cytotoxicity, and severity of colon cancer Nat Immunol 2021-08-13 [PMID: 34385712]
JaEn RI, FernAndez-Velasco M, TerrOn V et al. BML-111 treatment prevents cardiac apoptosis and oxidative stress in a mouse model of autoimmune myocarditis FASEB J. 2020-06-16 [PMID: 32543747] (ICC/IF, Mouse)	ICC/IF	Mouse
Glueck B, Han Y, Cresci G. Tributyrin Supplementation Protects Immune Responses and Vasculature and Reduces Oxidative Stress in the Proximal Colon of Mice Exposed to Chronic-Binge Ethanol Feeding Journal of Immunology Research 2018-08-19 [PMID: 30211234] (IHC-P, Mouse)	IHC-P	Mouse
Zahr A, Alcaide P, Yang J et al. Endomucin prevents leukocyte-endothelial cell adhesion and has a critical role under resting and inflammatory conditions. Nat Commun. 2016 Feb 02 [PMID: 26831939] (Flow, Human) Details: This citation used the PE version of this antibody.	Flow	Human
Rosengarten M, Hadad N, Solomonov Y et al. Cytosolic phospholipase A2 a has a crucial role in the pathogenesis of DSS-induced colitis in mice. Eur. J. Immunol. 2015-11-09 [PMID: 26548451] (IHC-P, Mouse) Details: Ly-6G6C antibody (clone NIMP-R14) was used for IHC-P for the identification of neutrophils in paraffin processed colon sections. The IHC assay involved blocking of non-specific reactivity with 20% normal rabbit serum for 20 minutes, use of primary antibody at 1:10 dilution in PBS for 1 hour at RT and detection using 1:200 dilution of biotinylated anti-rat IgG secondary followed by avidin-biotin complex/HRP-DAB with hematoxylin counterstaining (Figure 4B).	IHC-P	Mouse
Thangavel J, Malik AB, Elias HK et al. Combinatorial Therapy with Acetylation and Methylation Modifiers Attenuates Lung Vascular Hyperpermeability in Endotoxemia-Induced Mouse Inflammatory Lung Injury. Am. J. Pathol. 2014-06-12 [PMID: 24929240] (IF/IHC, Mouse) Details: Ly-6G6C antibody used as neutrophil-specific marker antibody; Figure 7 B and C - IHC of lung tissues depicting reduced LPS-induced neutrophil recruitment into the airspace after a sublethal dose of LPS in mice treated with Aza+TSA (combination of DNA methyl transferase inhibitor 5-Aza 2-deoxycytidine and histone deacetylase inhibitor trichostatin A) compared with mice untreated and treated with Aza alone or TSA alone.	IF/IHC	Mouse
Hadad N, Burgazliev O, Elgazar-Carmon V et al. Induction of cytosolic phospholipase a2alpha is required for adipose neutrophil infiltration and hepatic insulin resistance early in the course of high-fat feeding. Diabetes. 2013-09-01 [PMID: 23670971]
Kostarnoy AV, Gancheva PG, Logunov DY et al. Topical Bacterial Lipopolysaccharide Application Affects Inflammatory Response and Promotes Wound Healing J Interferon Cytokine Res. 2013-04-12 [PMID: 23581877]
Schmidt BA, Horsley V. Intradermal adipocytes mediate fibroblast recruitment during skin wound healing. Development 2013-04-01 [PMID: 23482487] (IF/IHC, ICC/IF, Mouse)	IF/IHC, ICC/IF	Mouse
Navarini AA, Lang KS, Verschoor A et al. Innate immune-induced depletion of bone marrow neutrophils aggravates systemic bacterial infections Proc Natl Acad Sci USA [PMID: 19351895] Details: Used the FITC form of this antibody.
Song Y, Coleman L, Shi J et al. Inflammation, endothelial injury, and persistent pulmonary hypertension in heterozygous BMPR2-mutant mice. Am J Physiol Heart Circ Physiol;295(2):H677-90. 2008-08-01 [PMID: 18552156] (IHC-P, Mouse)	IHC-P	Mouse
Elgazar-Carmon V, Rudich A, Hadad N et al. Neutrophils transiently infiltrate intra-abdominal fat early in the course of high-fat feeding. J Lipid Res;49(9):1894-903. 2008-09-01 [PMID: 18503031] (ICC/IF, IHC-P, Mouse)	ICC/IF, IHC-P	Mouse
Nagendra S, Schlueter AJ. Absence of cross-reactivity between murine Ly-6C and Ly-6G Cytometry A 2004-04-01 [PMID: 15057973] Details: This citation used the FITC version of this antibody.
de Vries B, Kohl J, Leclercq WK, Wolfs TG, van Bijnen AA, Heeringa P, Buurman WA. Complement factor C5a mediates renal ischemia-reperfusion injury independent from neutrophils. J Immunol;170(7):3883-9. 2003-04-01 [PMID: 12646657] (Mouse)		Mouse
Tacchini-Cottier F, Zweifel C, Belkaid Y. An immunomodulatory function for neutrophils during the induction of a CD4+ Th2 response in BALB/c mice infected with Leishmania major J Immunol [PMID: 10946291] Details: Used the FITC form of this antibody.
Lubberts E, Joosten LA, van Den Bersselaar L. Adenoviral vector-mediated overexpression of IL-4 in the knee joint of mice with collagen-induced arthritis prevents cartilage destruction J Immunol [PMID: 10510398] Details: Used the FITC form of this antibody.
Van Lent PL, Blom A, Holthuysen AE et al. Monocytes/macrophages rather than PMN are involved in early cartilage degradation in cationic immune complex arthritis in mice J Leukoc Biol [PMID: 9060449] Details: Used the FITC form of this antibody.
Lopez AF, Strath M, Sanderson CJ. Differentiation antigens on mouse eosinophils and neutrophils identified by monoclonal antibodies Br J Haematol 1984-07-01 [PMID: 6743568] Details: This citation used the FITC version of this antibody.
McLaren DJ, Strath M, Smithers SR. Schistosoma mansoni: evidence that immunity in vaccinated and chronically infected CBA/Ca mice is sensitive to treatment with a monoclonal antibody that depletes cutaneous effector cells Parasite Immunol [PMID: 3124065] Details: Used the FITC form of this antibody.
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