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Lubricin/PRG4 Antibody (1D5)

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Sandwich ELISA: Proteoglycan 4 Antibody (1D5) [H00010216-M02] - Detection limit for recombinant GST tagged PRG4 is approximately 3ng/ml as a capture antibody.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clone
1D5
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

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Lubricin/PRG4 Antibody (1D5) Summary

Immunogen
PRG4 (NP_005798, 1305 a.a. ~ 1404 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. ERAIGPSQTHTIRIQYSPARLAYQDKGVLHNEVKVSILWRGLPNVVTSAISLPNIRKPDGYDYYAFSKDQYYNIDVPSRTARAITTRSGQTLSKVWYNCP
Specificity
PRG4 - proteoglycan 4 (1D5)
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
PRG4
Purity
IgG purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Sandwich ELISA
  • Western Blot 1:500
Application Notes
Antibody Reactive Against Recombinant Protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
In 1x PBS, pH 7.4
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Lubricin/PRG4 Antibody (1D5)

  • bG174L6.2 (MSF: megakaryocyte stimulating factor )
  • bG174L6.2
  • CACP
  • FLJ32635
  • HAPO
  • Hemangiopoietin
  • JCAP
  • Lubricin
  • megakaryocyte stimulating factor
  • Megakaryocyte-stimulating factor
  • MSF
  • MSFproteoglycan 4, (megakaryocyte stimulating factor, articular superficial zoneprotein, camptodactyly, arthropathy, coxa vara, pericarditis syndrome)
  • PRG4
  • Proteoglycan 4
  • Superficial zone proteoglycan
  • SZP
  • SZPHAPOarticular superficial zone protein

Background

The protein encoded by this gene is a large proteoglycan specifically synthesized by chondrocytes located at the surface of articular cartilage, and also by some synovial lining cells. This protein contains both chondroitin sulfate and keratan sulfate glycosaminoglycans. It functions as a boundary lubricant at the cartilage surface and contributes to the elastic absorption and energy dissipation of synovial fluid. Mutations in this gene result in camptodactyly-arthropathy-coxa vara-pericarditis syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PRG4
Entrez
Uniprot