LC3B Antibody - BSA Free

Autophagy (macroautophagy) is a catabolic process which targets intracellular components such as proteins and organelles for degradation. Originally described as a bulk degradation process, current research supports its selective nature (1). Selective autophagy targets specific cellular components for degradation including the endoplasmic reticulum (2) (ER-phagy), mitochondria (3) (mitophagy), peroxisomes (3) (pexophagy), ribosomes (4) (ribophagy) and bacteria (5) (xenophagy). Autophagy relies on a newly formed phagophore, a membrane structure which elongates, sequesters cellular content, and fuses to form a double membrane vesicle known as the autophagosome. Fusion of autophagosomes with lysosomes gives rise to the autophagolysosome, where cellular components are degraded by lysosome hydrolases (1).

Autophagic flux is supported by autophagy-related proteins (Atgs) initially identified in yeast (6,7). The core autophagy machinery is comprised of 17 Atg proteins that play specific roles in autophagosome formation. Among these Atg proteins, Atg8 is not only involved in autophagosome formation but also functions in cargo selection. In mammals, several Atg8 homologues have been identified including microtubule-associated protein 1 light chain 3 alpha, beta and gamma - LC3A, LC3B, and LC3C (8) respectively, as well as GABA type A receptor-associated protein (GABARAP), GABARAP-Like1, and GABARAP-Like2 (9). LC3 (predicted molecular weight 14kD) is ubiquitously expressed and undergoes posttranslational processing after synthesis. First, the cysteine protease Atg4 cleaves a carboxy terminal sequence to generate the cytosolic form LC3-I. Next, E1-like (Atg7) and E2-like (Atg3) enzymes conjugate phosphatidylethanolamine to the newly exposed carboxyterminal glycine, generating LC3-II. Finally, the Atg12-Atg5-Atg16L1 complex participates in LC3 lipidation and autophagosome formation (10). LC3B-I to LC3B-II conversion correlates with autophagosome number and is considered the best marker to monitor autophagy.

References

1. Yu, L., Chen, Y., & Tooze, S. A. (2018). Autophagy pathway: Cellular and molecular mechanisms. Autophagy. https://doi.org/10.1080/15548627.2017.1378838

2. Forrester, A., De Leonibus, C., Grumati, P., Fasana, E., Piemontese, M., Staiano, L., ... Settembre, C. (2019). A selective ER -phagy exerts procollagen quality control via a Calnexin- FAM 134B complex. The EMBO Journal. https://doi.org/10.15252/embj.201899847

3. He, X., Zhu, Y., Zhang, Y., Geng, Y., Gong, J., Geng, J., ... Zhong, H. (2019). RNF34 functions in immunity and selective mitophagy by targeting MAVS for autophagic degradation. The EMBO Journal. https://doi.org/10.15252/embj.2018100978

4. Mathai, B., Meijer, A., & Simonsen, A. (2017). Studying Autophagy in Zebrafish. Cells. https://doi.org/10.3390/cells6030021

5. Losier, T. T., Akuma, M., McKee-Muir, O. C., LeBlond, N. D., Suk, Y., Alsaadi, R. M., ... Russell, R. C. (2019). AMPK Promotes Xenophagy through Priming of Autophagic Kinases upon Detection of Bacterial Outer Membrane Vesicles. Cell Reports. https://doi.org/10.1016/j.celrep.2019.01.062

6. Nakatogawa, H., Suzuki, K., Kamada, Y., & Ohsumi, Y. (2009). Dynamics and diversity in autophagy mechanisms: Lessons from yeast. Nature Reviews Molecular Cell Biology. https://doi.org/10.1038/nrm2708

7. Tsukada, M., & Ohsumi, Y. (1993). Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Letters. https://doi.org/10.1016/0014-5793(93)80398-E

8. Wild, P., McEwan, D. G., & Dikic, I. (2014). The LC3 interactome at a glance. Journal of Cell Science. https://doi.org/10.1242/jcs.140426

9. Igloi, G. L. (2001). Cloning, expression patterns, and chromosome localization of three human and two mouse homologues of GABAA receptor-associated protein. Genomics. https://doi.org/10.1006/geno.2001.6555

10. Glick, D., Barth, S., & Macleod, K. F. (2010). Autophagy: Cellular and molecular mechanisms. Journal of Pathology. https://doi.org/10.1002/path.2697

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 20 confirmed species: Human, Mouse, Rat, Alligator, Avian, Bacteria, Bovine, C. elegans, Canine, Chicken, Common marmoset, Drosophila melanogaster, Golden Syrian Hamster, Guinea Pig, Hamster, Invertebrate, Monkey, Porcine, Primate, Zebrafish.

We have publications tested in 23 applications: B/N, Chemotaxis, ELISA, EM, FLOW, Flow, Func, IB, ICC, ICC/IF, IF/IHC, IHC, IHC-Fr, IHC-P, IP, In Vivo, KD, KO, PLA, SDS-Page, SW, Simple Western, WB.

Showing Publications 1 - 10 of 1669. Show All 1669 Publications. Collapse Publications.

Publications using NB100-2220	Applications	Species
Lu Y. Mechanistic study on the inhibition of the late stage of basal autophagy progression by a natural compound (NAADP) and a synthetic small chemical (vacuolin-1). Thesis. 2014-01-01 (ICC/IF, WB, Human) Details: LC3B/MAP1LC3B antibody used in experiments involving HeLa cells for immunofluorescence analysis (ICC-IF, at 1:500 dilution) and Western blotting analysis (WB, at 1:1000 dilution),	ICC/IF, WB	Human
Lee E, Tran S, Juliani J et al. BECLIN1 is essential for intestinal homeostasis Research Square 2023-11-08 [PMID: 38378743] (WB)	WB
Figueroa K, Gross C, Atienza E et al. GGC expansion inZFHX3causes SCA4 and impairs autophagy medRxiv 2023-10-29 (WB)	WB
Chedid J The role of autophagy in TLR2-mediated alpha-synuclein accumulation in neurons. Thesis 2023-01-01 (WB, ICC/IF, Human)	WB, ICC/IF	Human
Kim J, Bae J, Park N et al. Inhibition of ubiquitin specific peptidase 14 (USP14) promotes ER-phagy by inducing ER stress in human hepatoma HepG2 cells Animal Cells and Systems 2023-12-11 (WB)	WB
Paparo L, Coppola S, Nocerino R et al. How advanced glycation end products could facilitate the occurrence of food allergy The Journal of allergy and clinical immunology 2023-11-30 [PMID: 38042501] (WB, Human)	WB	Human
Trovò L, Vaucher A, Pan Y et al. In vitro assessment of dietary bioactives for TFEB activation as a possible target to support cognitive and emotional wellbeing Journal of Functional Foods 2023-12-01
Wu MY, Ge YJ, Wang EJ et al. Enhancement of efferocytosis through biased FPR2 signaling attenuates intestinal inflammation EMBO molecular medicine 2023-11-22 [PMID: 37994307]
Li B, Ming H, Qin S et al. HSPA8 Activates Wnt/?-Catenin Signaling to Facilitate BRAF V600E Colorectal Cancer Progression by CMA-Mediated CAV1 Degradation Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023-11-16 [PMID: 37973552]
Ling JYM. Statins and Protein Prenylation in the Retina Thesis. 2017-01-01 (Human)		Human
Quintero-Espinosa D, Velez-Pardo C, Jimenez-Del-Rio M High Yield of Functional Dopamine-like Neurons Obtained in NeuroForsk 2.0 Medium to Study Acute and Chronic Rotenone Effects on Oxidative Stress, Autophagy, and Apoptosis International Journal of Molecular Sciences 2023-10-30 [PMID: 37958728] (FLOW, Human)	FLOW	Human
Carrasquillo Rodríguez JW, Uche O, Gao S et al. Differential reliance of CTD-nuclear envelope phosphatase 1 on its regulatory subunit in ER lipid synthesis and storage bioRxiv : the preprint server for biology 2023-10-13 [PMID: 37873275] (WB, Human)	WB	Human
Jabir MS. The interactions between inflammasome activation and induction of autophagy following Pseudomonas aeruginosa infection. 2014-01-01 (WB, FLOW, Mouse)	WB, FLOW	Mouse
Kopiasz ?, Dziendzikowska K, Oczkowski M et al. Low-molar-mass oat beta-glucan impacts autophagy and apoptosis in early stages of induced colorectal carcinogenesis in rats International Journal of Biological Macromolecules 2023-11-01 [PMID: 37924897] (WB, Rat)	WB	Rat
Ortigosa-Palomo A, Porras-Alcalá C, Quiñonero F et al. Antitumor activity of bengamide ii in a panel of human and murine tumor cell lines: In vitro and in vivo determination of effectiveness against lung cancer Biomedicine & Pharmacotherapy 2023-12-01 [PMID: 37924787] (WB) Details: Dilution 1:1000	WB
Seo Y, Lim C, Lee J et al. Sakurasosaponin inhibits lung cancer cell proliferation by inducing autophagy via AMPK activation Oncology letters 2023-12-01 [PMID: 37920436] (ICC/IF, Human) Details: 1:2000 ICC/IF diltuion	ICC/IF	Human
Xia Q, Zheng H, Li Y et al. SMURF1 controls the PPP3/calcineurin complex and TFEB at a regulatory node for lysosomal biogenesis Autophagy 2023-11-01 [PMID: 37909662] (ICC/IF, Human)	ICC/IF	Human
Naia L, Shimozawa M, Bereczki E et al. Mitochondrial hypermetabolism precedes impaired autophagy and synaptic disorganization in App knock-in Alzheimer mouse models Molecular psychiatry 2023-11-01 [PMID: 37907591] (IHC, Mouse)	IHC	Mouse
Kim J, Yang Y, Choi E et al. Effects of C-Peptide on Dexamethasone-Induced In Vitro and In Vivo Models as a Potential Therapeutic Agent for Muscle Atrophy International journal of molecular sciences 2023-10-21 [PMID: 37895113] (WB, Mouse)	WB	Mouse
Sánchez-Torres S, Orozco-Barrios C, Salgado-Ceballos H et al. Tibolone Improves Locomotor Function in a Rat Model of Spinal Cord Injury by Modulating Apoptosis and Autophagy International journal of molecular sciences 2023-10-18 [PMID: 37894971] (WB, Rat) Details: Dilution 1:2000	WB	Rat
Fu Y, Sacco O, DeBitetto E et al. Mitochondrial DNA breaks activate an integrated stress response to reestablish homeostasis Molecular cell 2023-10-19 [PMID: 37832546]
Popp L, Segatori L, Zinc Oxide Particles Induce Activation of the LysosomeAutophagy System ACS Omega Jan 31 2019 (ICC/IF, Human)	ICC/IF	Human
Santarelli R, Evangelista L, Pompili C et al. EBV infection of primary colonic epithelial cells causes inflammation, DDR and autophagy dysregulation, effects that may predispose to IBD and carcinogenesis Virus research 2023-10-12 [PMID: 37797746] (WB, Human)	WB	Human
Mubarak HA, Kamal MM, Mahmoud Y et al. The ameliorating effects of mesenchymal stem cells compared to ?-tocopherol on apoptosis and autophagy in streptozotocin-induced diabetic rats: Implication of PI3K/Akt signaling pathway and entero-insular axis Journal of cellular biochemistry 2023-10-05 [PMID: 37796145] (IHC)	IHC
Lee H, Cho S, Kim MJ et al. ApoE4-dependent lysosomal cholesterol accumulation impairs mitochondrial homeostasis and oxidative phosphorylation in human astrocytes Cell reports 2023-10-31 [PMID: 37777962]
Li N, Rao L, Zhao X et al. Chlorpromazine affects autophagy in association with altered Rag GTPase-mTORC1-TFEB signaling Frontiers in cell and developmental biology 2023-09-08 [PMID: 37745295] (WB, Human)	WB	Human
Hattori T, Fundora KA, Hamamoto K et al. ER stress elicits non-canonical CASP8 (caspase 8) activation on autophagosomal membranes to induce apoptosis Autophagy 2023-09-21 [PMID: 37733908] (WB, Human)	WB	Human
Bullen CK, Singh AK, Krug S et al. MDA5 RNA sensing pathway activation by Mycobacterium tuberculosis promotes innate immune subversion and pathogen survival JCI insight 2023-09-19 [PMID: 37725440] (ICC/IF, Mouse)	ICC/IF	Mouse
Krishnamoorthi S, Iyaswamy A, Sreenivasmurthy SG et al. PPAR? Ligand Caudatin Improves Cognitive Functions and Mitigates Alzheimer's Disease Defects By Inducing Autophagy in Mice Models Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2023-09-08 [PMID: 37682502]
DING Y, ZHI Q, ZUO Q et al. Transcriptome-based analysis of key signaling pathways affecting the formation of primordial germ cell in chickens Journal of Integrative Agriculture 2023-09-01 (WB, Chicken)	WB	Chicken
Ko SH, Choi JH, Kim JM. Bacteroides fragilis Enterotoxin Induces Autophagy through an AMPK and FoxO3-Pathway, Leading to the Inhibition of Apoptosis in Intestinal Epithelial Cells Toxins (Basel) 2023-09-03 [PMID: 37755970]
Waisner H, Lasnier S, Suma SM, Kalamvoki M Effects on exocytosis by two HSV-1 mutants unable to block autophagy Journal of virology 2023-09-15 [PMID: 37712703] (WB, Human)	WB	Human
Ershova ES, Savinova EA, Kameneva LV et al. Satellite III (1q12) Copy Number Variation in Cultured Human Skin Fibroblasts from Schizophrenic Patients and Healthy Controls Frontiers in bioscience (Landmark edition) 2023-08-31 [PMID: 37664948] (FLOW, Human)	FLOW	Human
Du Y, Shang Y, Qian Y et al. Plk1 promotes renal tubulointerstitial fibrosis by targeting autophagy/lysosome axis Cell Death & Disease 2023-08-29 [PMID: 37640723] (B/N, WB)	B/N, WB
Korsgen ME, Sun C, Seranova E et al. Analysis of autophagy deficiency and cytotoxicity in autophagy-deficient human embryonic stem cell-derived neurons STAR Protocols 2023-09-01 [PMID: 37624702] (ICC/IF, WB)	ICC/IF, WB
Zhang X, Shan G, Li N et al. An autophagy-inducing stapled peptide induces mitochondria dysfunction and triggers autotic cell death in triple-negative breast cancer Cell Death Discovery 2023-08-19 [PMID: 37598181] (B/N)	B/N
Sun, X;Zhou, L;Wang, Y;Deng, G;Cao, X;Ke, B;Wu, X;Gu, Y;Cheng, H;Xu, Q;Du, Q;Chen, H;Sun, Y; Single-cell analyses reveal cannabidiol rewires tumor microenvironment via inhibiting alternative activation of macrophage and synergizes with anti-PD-1 in colon cancer Journal of pharmaceutical analysis 2023-07-01 [PMID: 37577382] (FLOW)	FLOW
Lyu P Genome-wide identification of enhancers, transcription factors, and mechanisms that control skeletal muscle differentiation in cattle Thesis 2023-01-01
Ahmed M, Spicer C, Harley J et al. Amplifying the heat shock response ameliorates ALS and FTD pathology in mouse and human models. Research Square 2023-05-15 [PMID: 37516663] (IHC-Fr, Mouse)	IHC-Fr	Mouse
not provided w Immunoblots v1 protocols.io 2023-08-26 (WB)	WB
Pai YL, Lin YJ, Peng WH et al. The deubiquitinase Leon/USP5 interacts with Atg1/ULK1 and antagonizes autophagy Cell Death & Disease 2023-08-22 [PMID: 37607937]
Keary KM, Gu QH, Chen J, Li Z Dendritic distribution of autophagosomes underlies pathway-selective induction of LTD Cell reports 2023-07-28 [PMID: 37516958] (WB, Mouse) Details: Dilutions: 1:500	WB	Mouse
Anugula S, Li Z, Li Y et al. Rev1 deficiency induces a metabolic shift in MEFs that can be manipulated by the NAD+ precursor nicotinamide riboside Heliyon 2023-06-01 [PMID: 37484291]
Popp L, Segatori L, Zinc Oxide Particles Induce Activation of the LysosomeAutophagy System ACS Omega 2019-01-31 (WB, Human)	WB	Human
Kim JM, Dziobaka S, Yoon YE et al. OR2H2 Activates CAMKK?-AMPK-Autophagy Signaling Axis and Suppresses Senescence in VK2/E6E7 Cells Pharmaceuticals (Basel) 2023-08-29 [PMID: 37765029] (In Vivo, WB)	In Vivo, WB
Ma Q, Xin J, Peng Q et al. UBQLN2 and HSP70 participate in Parkin-mediated mitophagy by facilitating outer mitochondrial membrane rupture EMBO reports 2023-07-28 [PMID: 37501540]
Kissner V ATG14L and ZBTB16: Critical Roles in Aggrephagy in STHdhQ7/Q7 Striatal Neurons Thesis 2020-01-01
Liu Y, Hu Q, Pan Y et al. The apoptotic and autophagic effects of cast Au-Pt, and differently manufactured Co-Cr and cp-Ti on three-dimensional oral mucosal model Materials Science and Engineering: C Oct 1 2020 (ICC/IF, Human)	ICC/IF	Human
Zhang H, Zhang T, Sun L et al. ENO1 suppresses cancer cell ferroptosis by degrading the mRNA of iron regulatory protein 1 Research Square Oct 2 2020 (WB, Human)	WB	Human
Devi IK Regulation of hepatic lipid metabolism in CB1-/-and Abcb4-/--HBV surface protein transgenic mice Thesis Jan 1 2020
Fujiwara Y, Contu V, Kabuta C, et al. Discovery of a protein uptake pathway in lysosomes bioRxiv Aug 12 2020 (ICC/IF, Mouse)	ICC/IF	Mouse
Guo Z, Picataggi A, Ripoll C, et al. Apolipoprotein M attenuates doxorubicin cardiotoxicity by regulating transcription factor EB bioRxiv 2021-01-15 (WB, Human, Mouse)	WB	Human, Mouse
Li Z, Tian Y, Hong D et al. Mig-6 Promotes the Apoptosis and Inhibits of the Flux of Autophagy in HCC Cell Lines Through Modulating Mig-6/miR-193a-3p/TGF-beta 2 Axis Research Square Jul 9 2020 (WB, Human)	WB	Human
Wang D, Wu F, Zhu Y et al. Stilbene Derivatives from the Leaves and Stems of Bletilla striata and their Cytotoxicity and Autophagy Activity Chemistry of Natural Compounds 2021-05-24
Li A, Huang K, Guo J Et Al. SPAG1 Inhibits Cell Proliferation and Tumor Growth of Lung Adenocarcinoma via the AKT/mTORC1 Signaling Axis Research Square Jun 22 2021 (WB)	WB
Lu Y, Yuan R, Huang H et al. A Six Autophagy-Related LncRNA Signature Associated with Clinical Prognosis in Prostate Cancer Genetic Testing and Molecular Biomarkers Sep 1 2021 (WB, Human)	WB	Human
Lu Y, Yuan R, Huang H et al. A Six Autophagy-Related LncRNA Signature Associated with Clinical Prognosis in Prostate Cancer Genetic Testing and Molecular Biomarkers Sep 1 2021 (WB, Human)	WB	Human
Lagos Orellana JA Regulation of autophagy by inflammatory signals and its impacts on antigen presentation in B Cells Thesis 2021-01-01 (WB, ICC/IF)	WB, ICC/IF
Stojakovic A, Trushin S, Sheu A et al. Partial inhibition of mitochondrial complex I attenuates neurodegeneration and restores energy homeostasis and synaptic function in a symptomatic Alzheimers mouse model bioRxiv Jul 2 2020 (WB, Mouse)	WB	Mouse
Aivazidis S, Jain A, Anderson C et al. Down syndrome fibroblasts exhibit diminished autophagic clearance and endosomal dysfunction after serum starvation bioRxiv 2018-10-08 (ICC/IF, WB, Human)	ICC/IF, WB	Human
Sarkar C, Hegdekar N, Lipinski MM N-acetyl-L-leucine treatment attenuates neuronal cell death and suppresses neuroinflammation after traumatic brain injury in mice BioRxiv 2019-09-08 (WB, Mouse)	WB	Mouse
Choi G, Oh J, Lee H et al. Glucocorticoid-mediated ER-mitochondria contacts reduce AMPA receptor and mitochondria trafficking into cell terminus via microtubule destabilization. Mol. Carcinog. Nov 22 2018 (ICC/IF, WB, Human)	ICC/IF, WB	Human
Popp L, Segatori L, Zinc Oxide Particles Induce Activation of the Lysosome-Autophagy System ACS Omega 2019-01-31 (WB, Human)	WB	Human
Martinez-Vicente M, Franco-Iborra S, Plaza-Zabala A et al. Impairment of neuronal mitophagy by mutant huntingtin bioRxiv May 24 2018
Ravera S, Bertola N, Puddu A et al. Crosstalk between the Rod Outer Segments and Retinal Pigmented Epithelium in the Generation of Oxidative Stress in an In Vitro Model. Preprints 2023-06-30 [PMID: 37681906] (WB, Human)	WB	Human
del Rosario RCH, Poschmann J, Kumar P, Cheng CY Histone acetylome-wide association study of tuberculosis bioRxiv (WB, Human)	WB	Human
Chen Y, Wei P, Meng J et al. Harnessing Calcium Oxalate (CaOx ) Nanocrystal Induced Prodeath Autophagy for Attenuating Human Renal Proximal Tubular Epithelial Cell Injury Part. Part. Syst. Charact. Jun 12 2019 (WB, Human)	WB	Human
Fitzwalter BE Using Optogenetics and Biochemistry to Uncover How Autophagy Regulates Cell Death Thesis
Li Z, Jensen P, Abrigo J, Henriquez-Olguin C Phosphoproteomic identification of Xin as a novel requirement for skeletal muscle disuse atrophy bioRxiv 2019-05-28 (WB, Human)	WB	Human
Hamdan D The Role of CD9 in Regulating TNF-alpha-Induced Expression of A Disintegrin and Metalloprotease 17 (ADAM17) in Aortic Endothelial Cells Thesis
Zhou N, Wei ZX, Qi ZX Inhibition of autophagy triggers melatonin-induced apoptosis in glioblastoma cells assets.researchsquare.com
Singh AK, Praharaj M, Lombardo KA, Yoshida T Recombinant BCG overexpressing a STING agonist elicits trained immunity and improved antitumor efficacy in non-muscle invasive bladder bioRxiv 2020-01-01 (ICC/IF, Human)	ICC/IF	Human
Skoupilova H, Rak V, Pinkas J et al. The Cytotoxic Effect of Newly Synthesized Ferrocenes against Cervical Carcinoma Cells Alone and in Combination with Radiotherapy Applied Sciences May 28 2020 (WB, Human)	WB	Human
Ye Y, Tyndall ER, Bui V et al. Multifaceted membrane interactions of human Atg3 promote LC3-phosphatidylethanolamine conjugation during autophagy Nat Commun 2023-09-07 [PMID: 37679347] (In Vivo, WB)	In Vivo, WB
Wang K, Fu S, Dong L et al. Periplocin suppresses the growth of colorectal cancer cells by triggering LGALS3 (galectin 3)-mediated lysophagy Autophagy 2023-07-23 [PMID: 37471054]
Vo MT, Choi CY, Choi YB The mitophagy receptor NIX induces vIRF-1 oligomerization and interaction with GABARAPL1 for the promotion of HHV-8 reactivation-induced mitophagy PLoS pathogens 2023-07-01 [PMID: 37459327] (WB, Human)	WB	Human
Perez-Abshana L, Mendivil-Perez M, Velez-Pardo C, Jimenez-Del-Rio M Rotenone Blocks the Glucocerebrosidase Enzyme and Induces the Accumulation of Lysosomes and Autophagolysosomes Independently of LRRK2 Kinase in HEK-293 Cells International Journal of Molecular Sciences 2023-06-24 [PMID: 37445771] (FLOW, Human)	FLOW	Human
Tamiya H, Urushihara N, Shizuma K et al. SHARPIN Enhances Ferroptosis in Synovial Sarcoma Cells via NF-?B- and PRMT5-Mediated PGC1? Reduction Cancers (Basel) 2023-07-04 [PMID: 37444594]
Vámos A, Arianti R, Vinnai B et al. Human abdominal subcutaneous-derived active beige adipocytes carrying FTO rs1421085 obesity-risk alleles exert lower thermogenic capacity Frontiers in Cell and Developmental Biology 2023-06-14 [PMID: 37416800]
Reich M, Simon M, Polke B et al. Rescue of FTLD-associated TDP-43 pathology and neurodegeneration by peripheral AAV-mediated expression of brain-penetrant progranulin bioRxiv 2023-07-16
Fernandes MGF, Mohammadnia A, Pernin F et al. Mechanisms of metabolic stress induced cell death of human oligodendrocytes: relevance for progressive multiple sclerosis Acta neuropathologica communications 2023-07-05 [PMID: 37408029] (IHC, Human)	IHC	Human
Tripathi A, Periyasamy P, Guo M, Buch S HIV Tat-mediated altered oligodendrocyte maturation involves autophagy-lysosomal dysfunction NeuroImmune Pharmacology and Therapeutics 2023-06-26 (WB, Rat)	WB	Rat
Calcagni' A, Staiano L, Zampelli N et al. Loss of the batten disease protein CLN3 leads to mis-trafficking of M6PR and defective autophagic-lysosomal reformation Nature communications 2023-07-03 [PMID: 37400440] (WB)	WB
Kaur A, Venkatesan A, Kandarpa M et al. Lysosomal Degradation Pathways Target Mutant Calreticulin and the Thrombopoietin Receptor in Myeloproliferative Neoplasms bioRxiv 2023-07-17 (WB, Human)	WB	Human
McKinney JR, Seferovic MD, Major AM et al. Placental Autophagy and Viral Replication Co-localize in Human and Non-human Primate Placentae Following Zika Virus Infection: Implications for Therapeutic Interventions Frontiers in Virology 2021-09-17 [PMID: 37431450] (IHC)	IHC
Nopper SL, Schmidt KW, Ligeon LA, Münz C Analysis of LC3-Associated Phagocytosis and Antigen Presentation in Macrophages and B Cells Methods in molecular biology (Clifton, N.J.) 2023-06-26 [PMID: 37365477]
Chae CW, Yoon JH, Lim JR et al. TRIM16-mediated lysophagy suppresses high-gluocse-accumulated neuronal A? Autophagy 2023-06-25 [PMID: 37357416]
Zhang X, Evans TD, Chen S et al. Loss of Macrophage mTORC2 Drives Atherosclerosis via FoxO1 and IL-1? Signaling Circulation research 2023-06-23 [PMID: 37350264]
Korover N, Etzion S, Cherniak A et al. Functional defects in hiPSCs-derived cardiomyocytes from patients with a PLEKHM2-mutation associated with dilated cardiomyopathy and left ventricular non-compaction Biological research 2023-06-23 [PMID: 37349842] (ICC/IF, WB, Human) Details: 1:200 ICC/IF	ICC/IF, WB	Human
Iemolo A, De Risi M, Giordano N et al. Synaptic mechanisms underlying onset and progression of memory deficits caused by hippocampal and midbrain synucleinopathy NPJ Parkinson's disease 2023-06-16 [PMID: 37328503] (WB, Mouse)	WB	Mouse
Kim M, Chen C, Yaari Z et al. Nanosensor-based monitoring of autophagy-associated lysosomal acidification in vivo Nature chemical biology 2023-06-15 [PMID: 37322156]
Le W, Wang P, Al-Nusaif M et al. Pathological characteristics of axons and proteome patterns in midbrain dopaminergic neurodegeneration induced by WDR45-deficiency Research Square 2023-06-21 [PMID: 37292937] (ICC/IF)	ICC/IF
Boutry M, DiGiovanni L, Demers N et al. Arf1-PI4KIII? positive vesicles regulate phosphatidylinositol-3-phosphate signalling to facilitate the fission of lysosomal tubules bioRxiv 2023-03-25 [PMID: 37289133] (WB, Human)	WB	Human
Rabinowitsch AI, Maretzky T, Weskamp G et al. Analysis of the function of ADAM17 in iRhom2-curly-bare (cub) and Tylosis with Oesophageal Cancer (TOC) mutant mice Journal of cell science 2023-06-07 [PMID: 37282854]
Bellese G, Tagliatti E, Gagliani M et al. Neratinib Is a TFEB and TFE3 Activator That Potentiates Autophagy and Unbalances Energy Metabolism in ERBB2 Breast Cancer Cells SSRN Electronic Journal 2023-04-18 [PMID: 37269887]
Zhang J, Jiang N, Du C et al. HSF4 Transcriptionally Activates Autophagy by Regulating ATG9a During Lens Terminal Differentiation Investigative ophthalmology & visual science 2023-06-01 [PMID: 37266953] (ICC/IF, WB, Mouse)	ICC/IF, WB	Mouse
Hou X, Chen TH, Koga S et al. Alpha-synuclein-associated changes in PINK1-PRKN-mediated mitophagy are disease context dependent Brain pathology (Zurich, Switzerland) 2023-05-31 [PMID: 37259617] (WB, Human)	WB	Human
Jeong G, Shin S, Kim S et al. Ginsenoside Re prevents 3-methyladenine-induced catagen phase acceleration by regulating Wnt/ beta -catenin signaling in human dermal papilla cells Journal of Ginseng Research 2022-11-01 [PMID: 37252273] (WB, Human)	WB	Human
Wang L, Liu L, Han C et al. Histone Deacetylase 4 Inhibition Reduces Rotenone-Induced Alpha-Synuclein Accumulation via Autophagy in SH-SY5Y Cells Brain Sciences 2023-04-16 [PMID: 37190635] (WB, Mouse)	WB	Mouse
Panes J, Nguyen T, Gao H et al. Partial Inhibition of Complex I Restores Mitochondrial Morphology and Mitochondria-ER Communication in Hippocampus of APP/PS1 Mice Preprint 2023-01-28 [PMID: 37190020]
Jeong SH, An HK, Ha S, Yu SW. Distinct Signaling Pathways for Autophagy-Driven Cell Death and Survival in Adult Hippocampal Neural Stem Cells International Journal of Molecular Sciences 2023-05-05 [PMID: 37175992]
Kim BH, Koh HC The role of CK2 in the regulation of mitochondrial autophagy induced by rotenone Toxicology letters 2023-05-06 [PMID: 37156403] (WB, Human)	WB	Human
Harris, TJ;Liao, Y;Shi, W;Evangelista, M;Pal, B;Puthalakath, H;Aston, R;Mollard, R;Mariadason, JM;Lee, EF;Fairlie, WD; Induction of endoplasmic reticulum stress is associated with the anti-tumor activity of monepantel across cancer types Cancer medicine 2023-05-06 [PMID: 37148543] (WB, Human)	WB	Human
Kim YG, Seong C, Cho KA et al. Anti?tumor properties of FoxO1 in YD?9 oral squamous cell carcinoma cells Oncology reports 2023-06-01 [PMID: 37144504] (WB, Human)	WB	Human
Zhou D, Sun MH, Jiang WJ et al. Knock-down of YME1L1 induces mitochondrial dysfunction during early porcine embryonic development Frontiers in cell and developmental biology 2023-04-13 [PMID: 37123411] (WB, Porcine) Details: Dilutions: 1:1000	WB	Porcine
Lee E, Jung Y, Park Y et al. A distinct astrocyte subtype in the aging mouse brain characterized by impaired protein homeostasis Nature Aging 2022-08-01 [PMID: 37118130] (IHC-Fr, Mouse)	IHC-Fr	Mouse
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Bonavita R, Scerra G, Di Martino R et al. The HSPB1-p62/SQSTM1 functional complex regulates the unconventional secretion and transcellular spreading of the HD-associated mutant huntingtin protein Human molecular genetics 2023-03-27 [PMID: 36971475]
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Xie T, Feng M, Zhang X et al. Chicken CH25H inhibits ALV-J replication by promoting cellular autophagy Frontiers in Immunology 2023-02-15 [PMID: 36875122] (Func)	Func
Bensalem J, Hein LK, Hassiotis S et al. Modifying dietary protein impacts mTOR signaling and brain deposition of amyloid beta in a knock-in mouse model of Alzheimer's disease The Journal of nutrition 2023-03-02 [PMID: 36870538] (WB)	WB
Kim SH, Cho YS, Kim Y et al. Endolysosomal impairment by binding of amyloid beta or MAPT/Tau to V-ATPase and rescue via the HYAL-CD44 axis in Alzheimer disease Autophagy 2023-02-26 [PMID: 36843263] (WB, Mouse)	WB	Mouse
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Wang Y, Pan C, Zhang X et al. Mutant NPM1 maintains RASGRP3 protein stability via interaction with MID1 to promote acute myeloid leukemia cell proliferation and autophagy Journal of leukocyte biology 2023-02-24 [PMID: 36826998] (ICC/IF)	ICC/IF
Charrin E, Dabaghie D, Sen I et al. Soluble Klotho protects against glomerular injury through regulation of ER stress response Communications biology 2023-02-22 [PMID: 36813870] (WB, Mouse)	WB	Mouse
Kim MJ, Choi GE, Chae CW et al. Melatonin-mediated FKBP4 downregulation protects against stress-induced neuronal mitochondria dysfunctions by blocking nuclear translocation of GR Cell death & disease 2023-02-21 [PMID: 36810730] (IHC, ICC/IF, Human)	IHC, ICC/IF	Human
Xia Q, Li Y, Xu W et al. Enhanced liquidity of p62 droplets mediated by Smurf1 links Nrf2 activation and autophagy Cell & bioscience 2023-02-21 [PMID: 36810259] (ICC/IF, Human)	ICC/IF	Human
Wen H, Zuo Y, Li L et al. Hypoxic postconditioning restores mitophagy against transient global cerebral ischemia via Parkin-induced posttranslational modification of TBK1 Neurobiology of disease 2023-02-15 [PMID: 36805078] (WB, Rat)	WB	Rat
Huang CF, Hsieh YH, Yang SF et al. Mitophagy Effects of Protodioscin on Human Osteosarcoma Cells by Inhibition of p38MAPK Targeting NIX/LC3 Axis Cells 2023-01-21 [PMID: 36766737]
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Doganlar O, Doganlar ZB, Erdogan S, Delen E Antineoplastic multi-drug chemotherapy to sensitize tumors triggers multi-drug resistance and inhibits efficiency of maintenance treatment inglioblastoma cells EXCLI journal 2023-01-04 [PMID: 36660193] (WB, Human)	WB	Human
Hegdekar N, Sarkar C, Bustos S et al. Inhibition of autophagy in microglia and macrophages exacerbates innate immune responses and worsens brain injury outcomes Autophagy 2023-07-03 [PMID: 36652438] (IHC-Fr, IHC)	IHC-Fr, IHC
Ritzel R, Li Y, Lei Z Et al. Age-related Dysregulation of Autophagy Contributes to Microglial Dysfunction and Chronic Neurobehavioral Deficits After Traumatic Brain Injury Research Square Nov 11 2021 (IHC, Mouse)	IHC	Mouse
Liao YH, Wu JT, Hsieh IC et al. ARMS-NF-?B signaling regulates intracellular ROS to induce autophagy-associated cell death upon oxidative stress iScience 2023-02-17 [PMID: 36798436]
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Evans S, Ma X, Wang X et al. Targeting the Autophagy-Lysosome Pathway in a Pathophysiologically Relevant Murine Model of Reversible Heart�Failure JACC: Basic to Translational Science 2022-12-01 [PMID: 36644282] (WB)	WB
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Ma M, Cai B, Zhou Z et al. LncRNA-TBP mediates TATA-binding protein recruitment to regulate myogenesis and induce slow-twitch myofibers Research Square 2022-07-11 [PMID: 36635672]
Xu WN, Liu C, Zheng HL et al. Sesn2 Serves as a Regulator between Mitochondrial Unfolded Protein Response and Mitophagy in Intervertebral Disc Degeneration International Journal of Biological Sciences 2023-01-01 [PMID: 36632468] (B/N)	B/N
Beccari S, Sierra-Torre V, Valero J et al. Microglial phagocytosis dysfunction in stroke is driven by energy depletion and induction of autophagy Autophagy 2023-07-03 [PMID: 36622892] (EM, In Vivo)	EM, In Vivo
Lee C, Tsai J, Lee H et al. Blockage of Autophagy Increases Timosaponin AIII-Induced Apoptosis of Glioma Cells In Vitro and In Vivo Cells 2022-12-30 [PMID: 36611961] (WB, Human)	WB	Human
Guo L, Reed K, Carter A et al. Sleep-Disturbance-Induced Microglial Activation Involves CRH-Mediated Galectin 3 and Autophagy Dysregulation Cells 2022-12-30 [PMID: 36611953] (WB, Mouse)	WB	Mouse
Lee HJ, Kim SH, Kim YH et al. Nalfurafine Hydrochloride, a ?-Opioid Receptor Agonist, Induces Melanophagy via PKA Inhibition in B16F1 Cells Cells 2022-12-29 [PMID: 36611940] (WB)	WB
Higgins CB, Adams JA, Ward MH et al. The tetraspanin transmembrane protein CD53 mediates dyslipidemia and integrates inflammatory and metabolic signaling in hepatocytes The Journal of biological chemistry 2022-12-26 [PMID: 36581203] (WB, Mouse)	WB	Mouse
Hara K, Horikoshi Y, Morimoto M et al. TYRO3 promotes chemoresistance via increased LC3 expression in pancreatic cancer Translational oncology 2022-12-26 [PMID: 36577166] (IHC, Human)	IHC	Human
Condello M, Vona R, Meschini S Prunus spinosa Extract Sensitized HCT116 Spheroids to 5-Fluorouracil Toxicity, Inhibiting Autophagy International journal of molecular sciences 2022-12-17 [PMID: 36555736] (WB, Human) Details: Dilution used in WB 1:1000	WB	Human
Ben-Zvi H, Rabinski T, Ofir R et al. PLEKHM2 Loss of Function Impairs the Activity of iPSC-Derived Neurons via Regulation of Autophagic Flux International journal of molecular sciences 2022-12-17 [PMID: 36555735] (WB, Human) Details: Dilution used in WB 1:500	WB	Human
Wu Y, Kram H, Gempt J et al. ALDH1-Mediated Autophagy Sensitizes Glioblastoma Cells to Ferroptosis Cells 2022-12-12 [PMID: 36552781] (WB, Human)	WB	Human
Shi L, Song Z, Li C et al. HDAC6 Inhibition Alleviates Ischemia- and Cisplatin-Induced Acute Kidney Injury by Promoting Autophagy Cells 2022-12-07 [PMID: 36552715] (IHC-P, Mouse)	IHC-P	Mouse
Ying Z, Lv Q, Yao X et al. BAG3 promotes autophagy and suppresses NLRP3 inflammasome activation in Parkinson’s disease Annals of Translational Medicine 2022-11-01 [PMID: 36544667] (WB, Mouse)	WB	Mouse
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Yu XH, Xu XM, Zhang SX Low-dose dexamethasone promotes osteoblast viability by activating autophagy via the SGK1/FOXO3a signaling pathway Cell biology international 2022-12-01 [PMID: 36453461] (WB, Mouse)	WB	Mouse
Qiu-Jiao Z, Jian W, Ying Li et al PRKCA Promotes Mitophagy through the miR-15a-5p/PDK4 Axis to Relieve Sepsis-Induced Acute Lung Injury Infection and immunity 2022-11-30 [PMID: 36448837]
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Lyu P, Jiang H RNA-Sequencing Reveals Upregulation and a Beneficial Role of Autophagy in Myoblast Differentiation and Fusion Cells 2022-11-10 [PMID: 36428978] (WB, Mouse) Details: Dilution used for WB 1:1000	WB	Mouse
Kataura T, Sedlackova L, Otten EG et al. Autophagy promotes cell survival by maintaining NAD levels Developmental cell 2022-11-21 [PMID: 36413951]
Choi SW, Oh H, Park SY et al. Netrin-1 attenuates hepatic steatosis via UNC5b/PPAR gamma -mediated suppression of inflammation and ER stress Life sciences 2022-12-15 [PMID: 36400204] (WB, Mouse) Details: Dilution used in WB 1:1000	WB	Mouse
Sun S, Hou H, Ma G et al. The interaction between E3 ubiquitin ligase Parkin and mitophagy receptor PHB2 links inner mitochondrial membrane ubiquitination to efficient mitophagy The Journal of biological chemistry 2022-11-12 [PMID: 36379251] (WB, Human)	WB	Human
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Shaw A Thermogenic regulation of human abdominal and neck area derived adipocytes by mitophagy, irisin and BMP7 Thesis Jan 1 2022 (WB, ICC/IF, Human) Details: Dilution used for WB 1:2000	WB, ICC/IF	Human
Lora JN Regulation of ADAM17, a Key Molecule in Inflammation and EGF-R Signaling, by Its Cytoplasmic Domain Thesis Jan 1 2022
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Zuliani I, Di Domenico F, Gianni S Aberrant protein O-GlcNAcylation promotes Alzheimer-like neuropathology Thesis 2022-01-01 (WB, Mouse)	WB	Mouse
Choi M, Byun N, Hwang J et al. Effect of hydroxychloroquine and chloroquine on syncytial differentiation and autophagy in primary human trophoblasts Biomedicine & Pharmacotherapy May 1 2022 (WB, Human)	WB	Human
Maurin A, Parry L, B’chir W et al. GCN2 upregulates autophagy in response to short-term deprivation of a single essential amino acid Autophagy Reports Dec 31 2022 (WB)	WB
Dengler F, Sternberg F, Grages M et al. Adaptive mechanisms in no flow vs. low flow ischemia in equine jejunum epithelium: Different paths to the same destination Frontiers in Veterinary Science 2022-09-08 [PMID: 36157182] (WB)	WB
Kapahi P, Wilson K, Bar S et al. OXR1 maintains the retromer to delay brain aging under dietary restriction Research Square 2022-04-07
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Paul S, Dansithong W, Gandelman M et al. Staufen Impairs Autophagy in Neurodegeneration Annals of Neurology 2023-02-01 [PMID: 36151701] (WB)	WB
Fan YM, Zhang YL, Bahreyni A et al. Coxsackievirus Protease 2A Targets Host Protease ATG4A to Impair Autophagy Viruses 2022-09-13 [PMID: 36146840] (B/N, WB)	B/N, WB
Angelioudaki I, Koniaris E, Kataki A, Loukas Stoupis A Autophagy-related LC3B protein is highly expressed in panNENs Conference Jan 1 2022 (IHC-P, Human)	IHC-P	Human
Bouamar H, Broome L, Lathrop K et al. mTOR Inhibition Abrogates Human Mammary Stem Cells and Early Breast Cancer Progression Markers SSRN Electronic Journal Jul 10 2022 (Flow, Human)	Flow	Human
Evans S, Ma X, Wang X et al. Targeting the Autophagy-Lysosome Pathway in a Pathophysiologically Relevant Murine Model of Reversible Heart Failure JACC: Basic to Translational Science Oct 1 2022 (WB, Mouse)	WB	Mouse
Tufan AB Identification of Essential Components and Novel Regulators of Non-canonical and DNA damage-induced NF-kappaB Pathways Thesis Jan 1 2021
Li J, Wu D, Wang Z et al. The Role of Autophagy Regulator HMGB1 in Skeletal Muscle Autophagy After Eccentric Exercise Journal of Science in Sport and Exercise Oct 10 2022
Imam KMSU, Tian Y, Xin F et al. Lactucin, a Bitter Sesquiterpene from Cichorium intybus, Inhibits Cancer Cell Proliferation by Downregulating the MAPK and Central Carbon Metabolism Pathway Molecules (Basel, Switzerland) 2022-10-29 [PMID: 36364182] (WB, Human)	WB	Human
Hu J, Deng Y, Ding T et al. Lpcat3 deficiency promotes palmitic acid-induced 3T3-L1 mature adipocyte inflammation through enhanced ROS generation Acta Biochimica et Biophysica Sinica 2022-11-25 [PMID: 36331295]
Dowdell AS, Cartwright IM, Kitzenberg DA et al. Essential role for epithelial HIF-mediated xenophagy in control of Salmonella infection and dissemination Cell Reports 2022-09-27 [PMID: 36170839] (B/N)	B/N
Wilson J, Bowen E, DiGiacomo P et al. Beta-2 adrenergic receptor agonism alters astrocyte phagocytic activity and has potential applications to psychiatric disease Research Square 2022-10-25 (WB, Mouse)	WB	Mouse
Calis S, Dogan B, Durdagi S et al. A novel BH3 mimetic Bcl-2 inhibitor promotes autophagic cell death and reduces in vivo Glioblastoma tumor growth Cell death discovery 2022-10-29 [PMID: 36309485] (ICC/IF, Human)	ICC/IF	Human
Dong J, Guo C, Yang Z et al. Follicle-Stimulating Hormone Alleviates Ovarian Aging by Modulating Mitophagy- and Glycophagy-Based Energy Metabolism in Hens Cells 2022-10-18 [PMID: 36291137] (IHC-P, Chicken)	IHC-P	Chicken
Kim YS, Ko B, Kim DJ et al. Induction of the hepatic aryl hydrocarbon receptor by alcohol dysregulates autophagy and phospholipid metabolism via PPP2R2D Nature communications 2022-10-14 [PMID: 36241614]
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Hekman KE, Koss KM, Ivancic DZ et al. Autophagy Enhances Longevity of Induced Pluripotent Stem Cell-Derived Endothelium via mTOR-Independent ULK1 Kinase Stem cells translational medicine 2022-09-29 [PMID: 36173887] (WB, Human)	WB	Human
Kevin MK, Qin-Hua G, Jiji C, et al. Dendritic Distribution of Autophagosomes Underlies Pathway-Selective Induction of LTD SSRN Electronic Journal 2022 Nov 15 (WB)	WB
Carotenuto P, Romano A, Barbato A et al. Targeting the MITF/APAF-1 axis as salvage therapy for MAPK inhibitors in resistant melanoma Cell reports 2022-11-08 [PMID: 36351409] (WB, ICC/IF, Human)	WB, ICC/IF	Human
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Wang YC, Tsai MC, Chen YS et al. NPRL2 down-regulation facilitates the growth of hepatocellular carcinoma via the mTOR pathway and autophagy suppression Hepatology communications 2022-12-01 [PMID: 36321403] (WB, IHC-P, Human)	WB, IHC-P	Human
Zhang Y RGD-RE-1 Bifunctional Short Peptide Enhances the Interaction Between Rare Earth Nanomaterials and Cancer Cells and the Effect of Cell Autophagy Springer Theses 2022-01-01
Kim YH, Jo DS, Park NY et al. Inhibition of BRD4 Promotes Pexophagy by Increasing ROS and ATM Activation Cells 2022-09-12 [PMID: 36139416] (WB)	WB
Lo WT, Belabed H, K�c�kdisli M et al. Development of selective inhibitors of phosphatidylinositol 3-kinase C2? Nature Chemical Biology 2023-01-01 [PMID: 36109648] (ICC/IF)	ICC/IF
Wu HY, Trevino JG, Fang BL et al. Patient-Derived Pancreatic Cancer Cells Induce C2C12 Myotube Atrophy by Releasing Hsp70 and Hsp90 Cells 2022-09-03 [PMID: 36078164] (WB)	WB
Kshirsagar S, Alvir RV, Pradeepkiran JA et al. A Combination Therapy of Urolithin A+EGCG Has Stronger Protective Effects than Single Drug Urolithin A in a Humanized Amyloid Beta Knockin Mice for Late-Onset Alzheimer's Disease Cells 2022-08-27 [PMID: 36078067] (WB)	WB
Jang J, Koh JH, Kim Y et al. Balanced Free Essential Amino Acids and Resistance Exercise Training Synergistically Improve Dexamethasone-Induced Impairments in Muscle Strength, Endurance, and Insulin Sensitivity in Mice International Journal of Molecular Sciences 2022-08-27 [PMID: 36077132] (WB)	WB
Fevga C, Tesson C, Carreras Mascaro A et al. PTPA variants and impaired PP2A activity in early-onset parkinsonism with intellectual disability Brain 2023-04-19 [PMID: 36073231] (WB)	WB
Ainembabazi D, Geng X, Gavande NS et al. Synthesis and Biological Evaluation of Cardiac Glycosides for Cancer Therapy by Targeting the DNA Damage Response ChemMedChem 2022-11-04 [PMID: 36054918]
Zhang F, Chen Q, Chen P et al. The lncRNA CRNDE is regulated by E2F6 and sensitizes gastric cancer cells to chemotherapy by inhibiting autophagy Journal of Cancer 2022-08-08 [PMID: 36046639] (WB, Human) Details: 1:1000 WB dilution	WB	Human
Imberechts D, Kinnart I, Wauters F et al. DJ-1 is an essential downstream mediator in PINK1/parkin-dependent mitophagy Brain 2022-12-19 [PMID: 36039535] (ICC/IF, WB)	ICC/IF, WB
Kim HJ, Lee PCW, Hong JH Lamin-A/C Is Modulated by the Involvement of Histamine-Mediated Calcium/Calmodulin-Dependent Kinase II in Lung Cancer Cells International journal of molecular sciences 2022-08-13 [PMID: 36012358] (WB, Human)	WB	Human
Wang S, Wang G, Wu W et al. Autophagy activation by dietary piceatannol enhances the efficacy of immunogenic chemotherapy Frontiers in Immunology 2022-08-01 [PMID: 35979349]
Sun Y, Guan X, Zhang T et al. Regulation of the sensitivity of hepatocarcinoma cells by ORMDL3, to sorafenib by autophagy Medical oncology (Northwood, London, England) 2022-08-16 [PMID: 35972600] (IHC-P, Mouse)	IHC-P	Mouse
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Yu J, Liu T, Gao Z et al. Akkermansia muciniphila Colonization Alleviating High Fructose and Restraint Stress-Induced Jejunal Mucosal Barrier Disruption Nutrients 2022-07-30 [PMID: 35956340] (WB, Mouse) Details: Dilution used 1:1000, jejunum samples from female C57BL/6J mice	WB	Mouse
Bertola N, Degan P, Cappelli E, Ravera S Mutated FANCA Gene Role in the Modulation of Energy Metabolism and Mitochondrial Dynamics in Head and Neck Squamous Cell Carcinoma Cells 2022-07-30 [PMID: 35954197] (WB, Human) Details: Dilution used 1:1000	WB	Human
Oh H, Cho W, Abd El-Aty A et al. Resolvin D3 Improves the Impairment of Insulin Signaling in Skeletal Muscle and Nonalcoholic Fatty Liver Disease Through AMPK/Autophagy-Associated Attenuation of ER Stress SSRN Electronic Journal 2022-07-10 [PMID: 35948170]
Bock J, KUhnle N, Knopf JD et al. Rhomboid protease RHBDL4 promotes retrotranslocation of aggregation-prone proteins for degradation Cell reports 2022-08-09 [PMID: 35947953] (WB) Details: Supplementary Figure S5.	WB
Li Y, Lei Z, Ritzel RM Et al. Impairment of autophagy after spinal cord injury potentiates neuroinflammation and motor function deficit in mice Theranostics 2022-08-01 [PMID: 35910787] (IHC-P, WB, Mouse) Details: Citation using the Alexa Fluor 647 version of this antibody.	IHC-P, WB	Mouse
Baytas O, Kauer J, Morrow E Loss of mitochondrial enzyme GPT2 causes early neurodegeneration in locus coeruleus Neurobiology of Disease 2022-07-01 [PMID: 35908744] (IHC-Fr, Mouse)	IHC-Fr	Mouse
Dong AQ, Yang YP, Jiang SM et al. Pramipexole inhibits astrocytic NLRP3 inflammasome activation via Drd3-dependent autophagy in a mouse model of Parkinson's disease Acta pharmacologica Sinica 2022-07-27 [PMID: 35896696] (WB, Mouse)	WB	Mouse
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Peischard S, Moller M, Disse P Et al. Virus-induced inhibition of cardiac pacemaker channel HCN4 triggers bradycardia in human-induced stem cell system Cell Mol Life Sci 2022-07-21 [PMID: 35864219] (ICC, Human) Details: Citation using the Alexa Fluor 350 version of this antibody.	ICC	Human
Danese A, Patergnani S, Maresca A et al. Pathological mitophagy disrupts mitochondrial homeostasis in Leber's hereditary optic neuropathy Cell reports 2022-07-19 [PMID: 35858578]
Das P, Brahmachari G, Chatterjee K, Choudhuri T. Synthetic antioxidants from a natural source can overtake the oncogenic stress management system and activate the�stress?sensitized death of KSHV?infected cancer cells International Journal of Molecular Medicine 2022-07-13 [PMID: 35856421]
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Wrobel L, Hill SM, Djajadikerta A et al. Compounds activating VCP D1 ATPase enhance both autophagic and proteasomal neurotoxic protein clearance Nature communications 2022-07-16 [PMID: 35842429] (WB, Human) Details: Supplementary fig. 3, Dilution 1:1000	WB	Human
Silva-Rojas R, P�rez-Gu�rdia L, Lafabrie E et al. Silencing of the Ca(2+) Channel ORAI1 Improves the Multi-Systemic Phenotype of Tubular Aggregate Myopathy (TAM) and Stormorken Syndrome (STRMK) in Mice International Journal of Molecular Sciences 2022-06-23 [PMID: 35805973]
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Singh VK, Khan A, Xu Y et al. Antibody-Mediated LILRB2-Receptor Antagonism Induces Human Myeloid-Derived Suppressor Cells to Kill Mycobacterium tuberculosis Frontiers in Immunology 2022-06-10 [PMID: 35757769] (WB)	WB
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Braatz EM, Andr� EA, Liu JP, Zeitlin SO. Characterization of a Knock-In Mouse Model with a Huntingtin Exon 1 Deletion Journal of Huntington's Disease 2021-11-09 [PMID: 34459410] (IHC, WB)	IHC, WB
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Xiang P, Mohamud Y, Luo H SNAP47 Interacts with ATG14 to Promote VP1 Conjugation and CVB3 Propagation Cells 2021-08-20 [PMID: 34440910] (WB, Human)	WB	Human
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Silva-Rojas R, Charles A, Djeddi S Et Al. Pathophysiological Effects of Overactive STIM1 on Murine Muscle Function and Structure Cells 2021-07-08 [PMID: 34359900] (WB)	WB
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Tong Bc, Wu Aj, Huang As Et Al. Lysosomal TPCN (two pore segment channel) inhibition ameliorates beta-amyloid pathology and mitigates memory impairment in Alzheimer disease Autophagy 2021-07-27 [PMID: 34313551] (WB)	WB
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Weng SW, Liu TT, Eng HL et al. Autophagy Plays a Role in the CUL4A-Related Poor Prognosis of Intrahepatic Cholangiocarcinoma Pathology and Oncology Research 2021-02-23 [PMID: 34257560]
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Wu Z, Wang F, Hu L et al. Inhibition of endoplasmic reticulum stress-related autophagy attenuates MCLR-induced apoptosis in zebrafish testis and mouse TM4 cells Ecotoxicology and environmental safety 2021-06-25 [PMID: 34175825] (IF/IHC, ICC/IF, Mouse)	IF/IHC, ICC/IF	Mouse
Cachon-Gonzalez Mb, Wang S, Cox Tm Expression of Ripk1 and DAM genes correlates with severity and progression of Krabbe disease Human molecular genetics 2021-06-25 [PMID: 34172992] (WB)	WB
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De Risi M, Tufano M, Alvino FG et al. Altered heparan sulfate metabolism during development triggers dopamine-dependent autistic-behaviours in models of lysosomal storage disorders Nature communications 2021-06-09 [PMID: 34108486] (WB, Mouse)	WB	Mouse
Chen J, Wang D, Zong Y, Yang X. DHA Protects Hepatocytes from Oxidative Injury through GPR120/ERK-Mediated Mitophagy International Journal of Molecular Sciences 2021-05-26 [PMID: 34073582] (ICC/IF, IHC-P)	ICC/IF, IHC-P
Liu EA, Mori E, Hamasaki F, Lieberman AP. TDP-43 proteinopathy occurs independently of autophagic substrate accumulation and underlies nuclear defects in Niemann-Pick C disease Neuropathology and Applied Neurobiology 2021-12-01 [PMID: 34048071]
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Kuramoto K, Kim YJ, Hong JH, He C The autophagy protein Becn1 improves insulin sensitivity by promoting adiponectin secretion via exocyst binding Cell reports 2021-05-25 [PMID: 34038729]
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Li X, Yang KB, Chen W et al. CUL3 (cullin 3)-mediated ubiquitination and degradation of BECN1 (beclin 1) inhibit autophagy and promote tumor progression Autophagy 2021-05-12 [PMID: 33977871]
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Lin F, Liu Y, Tang L et al. Rapamycin protects against aristolochic acid nephropathy in mice by potentiating mammalian target of rapamycin mediated autophagy Molecular medicine reports Jul 1 2021 [PMID: 33955513] (ICC/IF, Human)	ICC/IF	Human
Lin F, Liu Y, Tang L et al. Rapamycin protects against aristolochic acid nephropathy in mice by potentiating mammalian target of rapamycin?mediated autophagy Molecular Medicine Reports 2021-05-05 [PMID: 33955513] (ICC/IF)	ICC/IF
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Hegdekar N, Lipinski M, Sarkar C N-Acetyl-l-leucine improves functional recovery and attenuates cortical cell death and neuroinflammation after traumatic brain injury in mice Scientific Reports 2021-12-01 [PMID: 33927281] (IF/IHC, WB, Mouse)	IF/IHC, WB	Mouse
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Li XL, Zhou J, Xia CJ et al. PRIMA 1met induces autophagy in colorectal cancer cells through upregulation of the mTOR/AMPK ULK1 Vps34 signaling cascade Oncology reports 2021-05-01 [PMID: 33846805] (WB, Human)	WB	Human
Tyutyunyk-Massey L, Sun Y, Dao N et al. Autophagy-Dependent Sensitization of Triple-Negative Breast Cancer Models to Topoisomerase II Poisons by Inhibition of the Nucleosome Remodeling Factor Molecular Cancer Research 2021-08-01 [PMID: 33811160] (WB)	WB
Napolitano F, Bruno G, Terracciano C et al. Rare Variants in Autophagy and Non-Autophagy Genes in Late-Onset Pompe Disease: Suggestions of Their Disease-Modifying Role in Two Italian Families International Journal of Molecular Sciences 2021-03-31 [PMID: 33807278]
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Xu S, Zhou Z, Peng X et al. EBV-LMP1 promotes radioresistance by inducing protective autophagy through BNIP3 in nasopharyngeal carcinoma Cell death & disease 2021-04-01 [PMID: 33795637] (WB, Human)	WB	Human
Li D, Vogel P, Li-Harms X et al. ATG14 and RB1CC1 play essential roles in maintaining muscle homeostasis Autophagy 2021-04-14 [PMID: 33794726]
Bensalem J, Fourrier C, Hein LK et al. Inhibiting mTOR activity using AZD2014 increases autophagy in the mouse cerebral cortex Neuropharmacology 2021-03-29 [PMID: 33794244] (WB, Mouse)	WB	Mouse
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Zhou X, Sun T, Meng Y et al. BET inhibitors combined with chemotherapy synergistically inhibit the growth of NSCLC cells Oncology reports 2021-05-01 [PMID: 33760217]
Dai H, Hu W, Zhang L et al. FGF21 facilitates autophagy in prostate cancer cells by inhibiting the PI3K-Akt-mTOR signaling pathway Cell death & disease 2021-03-22 [PMID: 33753729] (ICC/IF, Human)	ICC/IF	Human
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Tavassoly O, Del Cid Pellitero E, Larroquette F et al. Pharmacological Inhibition of Brain EGFR Activation By a BBB-penetrating Inhibitor, AZD3759, Attenuates alpha-synuclein Pathology in a Mouse Model of alpha-Synuclein Propagation Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2021-03-12 [PMID: 33713002]
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De Leo MG, Berger P, Mayer A. WIPI1 promotes fission of endosomal transport carriers and formation of autophagosomes through distinct mechanisms Autophagy 2021-11-02 [PMID: 33685363]
Yu Y, Men S, Zhang Y miR-20a-5p ameliorates ovalbumin (OVA)-induced mouse model of allergic asthma through targeting ATG7-regulated cell death, fibrosis and inflammation International immunopharmacology 2021-03-06 [PMID: 33684878] (ICC/IF, WB, Mouse)	ICC/IF, WB	Mouse
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Ryu HY, Kim LE, Jeong H et al. GSK3B induces autophagy by phosphorylating ULK1 Experimental & molecular medicine 2021-03-02 [PMID: 33654220]
Liu N, Lin MM, Huang SS et al. NADPH and Mito-Apocynin Treatment Protects Against KA-Induced Excitotoxic Injury Through Autophagy Pathway Frontiers in Cell and Developmental Biology 2021-02-11 [PMID: 33644049] (WB)	WB
Zheng X, Lin W, Jiang Y et al. Electroacupuncture ameliorates beta-amyloid pathology and cognitive impairment in Alzheimer disease via a novel mechanism involving activation of TFEB (transcription factor EB) Autophagy 2021-02-23 [PMID: 33622188] (WB)	WB
Kim YJ, Kong Q, Yamamoto S et al. An autophagy-related protein Becn2 regulates cocaine reward behaviors in the dopaminergic system Science advances 2021-02-01 [PMID: 33608268] (B/N) Details: Co-immunoprecipitaiton performed to analyze Becn2-GASP1 interactions in mouse Neuro2A cells.	B/N
Zhang Z, Zhu D, Zhang X et al. Tanshinone IIA regulates fibroblast proliferation and migration and post-surgery arthrofibrosis through the autophagy-mediated PI3K and AMPK-mTOR signaling pathway American journal of translational research 2021-02-15 [PMID: 33594310] (IF/IHC)	IF/IHC
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Shao Z, Dou S, Zhu J et al. Apelin-36 Protects HT22 Cells Against Oxygen-Glucose Deprivation/Reperfusion-Induced Oxidative Stress and Mitochondrial Dysfunction by Promoting SIRT1-Mediated PINK1/Parkin-Dependent Mitophagy Neurotox Res 2021-02-13 [PMID: 33580874] (WB, Mouse)	WB	Mouse
Uchida K, Inoue K, Hasegawa Y et al. Endogenous testosterone reduces hepatic lipid accumulation in protein-restricted male rats Nutrition 2020-12-01 [PMID: 33545537] (WB, Rat)	WB	Rat
Gonnella R, Gilardini Montani MS, Guttieri L et al. IRE1 Alpha/XBP1 Axis Sustains Primary Effusion Lymphoma Cell Survival by Promoting Cytokine Release and STAT3 Activation Biomedicines 2021-01-27 [PMID: 33513694] (WB, Human)	WB	Human
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Yu SH, Palanisamy K, Sun KT, et al. Human antigen R regulates hypoxia-induced mitophagy in renal tubular cells through PARKIN/BNIP3L expressions Journal of cellular and molecular medicine 2021-01-26 [PMID: 33496385] (ICC/IF, WB, Human)	ICC/IF, WB	Human
Li XJ, Zhang YY, Fu YH et al. Gossypol, a novel modulator of VCP, induces autophagic degradation of mutant huntingtin by promoting the formation of VCP/p97-LC3-mHTT complex Acta pharmacologica Sinica 2021-01-25 [PMID: 33495516]
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Wilhelm R, Eckes T, Imre G, et al. C6 Ceramide (d18:1/6:0) as a Novel Treatment of Cutaneous T Cell Lymphoma Cancers 2021-01-13 [PMID: 33450826] (WB, Human)	WB	Human
Ye Y, Tyndall ER, Bui V, et al. An N-terminal conserved region in human Atg3 couples membrane curvature sensitivity to conjugase activity during autophagy Nature communications 2021-01-14 [PMID: 33446636] (WB)	WB
Fei M, Zhang L, Wang H et al. Inhibition of Cathepsin S Induces Mitochondrial Apoptosis in Glioblastoma Cell Lines Through Mitochondrial Stress and Autophagosome Accumulation Frontiers in Oncology 2020-12-23 [PMID: 33425712] (B/N)	B/N
Wu CH, Gan CH, Li LH et al. A Synthetic Small Molecule F240B Decreases NLRP3 Inflammasome Activation by Autophagy Induction Frontiers in Immunology 2020-12-18 [PMID: 33424855]
Stojakovic A, Trushin S, Sheu A et al. Partial inhibition of mitochondrial complex I ameliorates Alzheimer's disease pathology and cognition in APP/PS1 female mice Communications Biology 2021-01-08 [PMID: 33420340] (B/N, In Vivo)	B/N, In Vivo
Zhao T, Zheng T, Yu H, et al. Autophagy impairment as a key feature for acetaminophen-induced ototoxicity Cell death & disease 2021-01-04 [PMID: 33414397] (WB, Mouse)	WB	Mouse
Meng F, Zhou M, Xiao Y, et al. A deafness-associated tRNA mutation caused pleiotropic effects on the m1G37 modification, processing, stability and aminoacylation of tRNAIle and mitochondrial translation Nucleic acids research 2021-01-25 [PMID: 33398350] (WB, Human)	WB	Human
Ling J, Cai H, Lin M, et al. RTN1-C mediates cerebral ischemia/reperfusion injury via modulating autophagy Acta biochimica et biophysica Sinica 2020-12-29 [PMID: 33372676] (WB, Rat)	WB	Rat
Chen X, Wang Y, Qu N, et al. PLC gamma 1 inhibition-driven autophagy of IL-1 beta -treated chondrocyte confers cartilage protection against osteoarthritis, involving AMPK, Erk and Akt Journal of cellular and molecular medicine 2020-12-28 [PMID: 33372388] (IF/IHC, WB, Human)	IF/IHC, WB	Human
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Dong X, Yang Y, Zou Z et al. Sorting nexin 5 mediates virus-induced autophagy and immunity Nature 2020-12-16 [PMID: 33328639]
Yang J, Li ZD, Hou CY et al. EM-2 inhibited autophagy and promoted G2/M phase arrest and apoptosis by activating the JNK pathway in hepatocellular carcinoma cells Acta pharmacologica Sinica 2020-12-14 [PMID: 33318625]
Fourrier C, Bryksin V, Hattersley K et al. Comparison of chloroquine-like molecules for lysosomal inhibition and measurement of autophagic flux in the brain Biochemical and biophysical research communications 2020-12-11 [PMID: 33316543] (WB, Mouse)	WB	Mouse
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Bandyopadhaya A, Tzika AA, Rahme LG Pseudomonas aeruginosa Quorum Sensing Molecule Alters Skeletal Muscle Protein Homeostasis by Perturbing the Antioxidant Defense System MBio 2019-10-01 [PMID: 31575771] (WB, Mouse)	WB	Mouse
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Higgins CB, Zhang Y, Mayer AL et al. Hepatocyte ALOXE3 is induced during adaptive fasting and enhances insulin sensitivity by activating hepatic PPARg JCI Insight 2018-08-23 [PMID: 30135298] (WB, Mouse)	WB	Mouse
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Thomas MB, Gnanadhas DP, Dash PK et al. Modulating cellular autophagy for controlled antiretroviral drug release Nanomedicine (Lond) 2018-08-21 [PMID: 30129397] (WB, Human)	WB	Human
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Wei X, Zhang H, Wei G et al. Honokiol Protects against Anti-B1-Adrenergic Receptor Autoantibody-Induced Myocardial Dysfunction via Activation of Autophagy. Oxidative Medicine and Cellular Longevity 2018-07-18 [PMID: 30116474] (WB, Rat)	WB	Rat
Li C, Zhang Y, Cheng X et al. PINK1 and PARK2 Suppress Pancreatic Tumorigenesis through Control of Mitochondrial Iron-Mediated Immunometabolism Dev. Cell 2018-08-20 [PMID: 30100261] (WB, Mouse)	WB	Mouse
Li , Wang C, Li Z et al. Nano-sized Al2O3 particle-induced autophagy reduces osteolysis in aseptic loosening of total hip arthroplasty by negative feedback regulation of RANKL expression in fibroblasts Cell Death Dis 2018-08-12 [PMID: 30082761] (WB, Human)	WB	Human
Tang Y, Blomenkamp KS, Fickert P et al. NorUDCA promotes degradation of a1-antitrypsin mutant Z protein by inducing autophagy through AMPK/ULK1 pathway PLoS ONE 2018-08-01 [PMID: 30067827] (WB, Human)	WB	Human
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Li CX, Cui LH, Zhuo YZ et al. Inhibiting autophagy promotes collagen degradation by regulating matrix metalloproteinases in pancreatic stellate cells. Life Sci. 2018-07-26 [PMID: 30056017] (ICC/IF, Rat)	ICC/IF	Rat
Mamais A, Manzoni C, Nazish I et al. Analysis of macroautophagy related proteins in G2019S LRRk2 Parkinson's disease brains with Lewy Body pathology. Brain Res. 2018-07-25 [PMID: 30055128] (WB, Human)	WB	Human
Pavel M, Renna M, Park SJ et al. Contact inhibition controls cell survival and proliferation via YAP/TAZ-autophagy axis. Nat Commun. 2018-07-27 [PMID: 30054475] (WB, Mouse, Human)	WB	Mouse, Human
Takahashi Y, He H, Tang Z et al. An autophagy assay reveals the ESCRT-III component CHMP2A as a regulator of phagophore closure. Nat Commun. 2018-07-20 [PMID: 30030437] (WB, Human)	WB	Human
Dethlefsen MM, Halling JF, Moller HD et al. Regulation of apoptosis and autophagy in mouse and human skeletal muscle with aging and lifelong exercise training. Exp. Gerontol. 2018-07-17 [PMID: 30030137] (WB, Human, Mouse)	WB	Human, Mouse
Zhang J, Dai W, Geng P et al. Midazolam Enhances Mutant Huntingtin Protein Accumulation via Impairment of Autophagic Degradation In Vitro. Cell. Physiol. Biochem. 2018-07-19 [PMID: 30025395] (WB, ICC/IF, Rat)	WB, ICC/IF	Rat
Schiavon CR, Griffin ME, Pirozzi M et al. Compositional Complexity of Rods and Rings. Mol. Biol. Cell. 2018-07-19 [PMID: 30024290] (ICC/IF, Human)	ICC/IF	Human
Ibanez-Cabellos JS, Aguado C, Perez-Cremades D et al. Extracellular histones activate autophagy and apoptosis via mTOR signaling in human endothelial cells. Biochim. Biophys. Acta. 2018-07-11 [PMID: 30006152] (WB, Human)	WB	Human
Sun W, Yue J. TPC2 mediates autophagy progression and extracellular vesicle secretion in cancer cells. Exp. Cell Res. 2018-07-07 [PMID: 29990474] (WB, Human)	WB	Human
Chen H, Qian Y, Yu S et al. Early onset developmental delay and epilepsy in pediatric patients with WDR45 variants. Eur J Med Genet. 2018-07-06 [PMID: 29981852] (ICC/IF, Human)	ICC/IF	Human
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Latomanski EA, Newton HJ. Interaction between autophagic vesicles and the Coxiella-containing vacuole requires CLTC (clathrin heavy chain). Autophagy 2018-07-29 [PMID: 29973118] (WB, Human)	WB	Human
Woo H, Hong CJ, Jung S et al. Chronic restraint stress induces hippocampal memory deficits by impairing insulin signaling. Mol Brain. 2018-07-03 [PMID: 29970188] (WB, Mouse)	WB	Mouse
Thangaraj A, Periyasamy P, Liao K et al. HIV-1 TAT-mediated microglial activation: role of mitochondrial dysfunction and defective mitophagy Autophagy. 2018-09-15 [PMID: 29966509] (WB, Rat)	WB	Rat
Zhang G, Luk BT, Hamidy M et al. Induction of a Na+/K+-ATPase-dependent form of autophagy triggers preferential cell death of human immunodeficiency virus type-1-infected macrophages Autophagy. 2018-07-22 [PMID: 29962265] (WB, Human)	WB	Human
Dethlefsen MM, kristensen CM, Tondering AS et al. Impact of liver PGC-1a on exercise and exercise training-induced regulation of hepatic autophagy and mitophagy in mice on HFF. Physiol Rep. 2018-07-01 [PMID: 29962089] (WB, Mouse)	WB	Mouse
Lin HH, Chung Y, Cheng CT et al. Autophagic reliance promotes metabolic reprogramming in oncogenic KRAS-driven tumorigenesis Autophagy. 2018-10-31 [PMID: 29956571] (WB, IHC-P, Mouse)	WB, IHC-P	Mouse
Shen T, Zhu W et al. Lactosylated N-Alkyl polyethylenimine coated iron oxide nanoparticles induced autophagy in mouse dendritic cells. Regen Biomater 2018-01-06 [PMID: 29942646] (WB, Mouse)	WB	Mouse
Wang W, Xia Z, FarrE JC et al. TRIM37 deficiency induces autophagy through deregulating the MTORC1-TFEB axis Autophagy. 2018-09-20 [PMID: 29940807] (WB, Human)	WB	Human
Park SM, Lim JS, Ramakrishina S et al. Brain Somatic Mutations in MTOR Disrupt Neuronal Ciliogenesis, Leading to Focal Cortical Dyslamination Neuron 2018-06-09 [PMID: 29937275] (ICC/IF, Human)	ICC/IF	Human
Al-Ramahi I, Lu B, Di Paola S et al. High-Throughput Functional Analysis Distinguishes Pathogenic, Nonpathogenic, and Compensatory Transcriptional Changes in Neurodegeneration Cell Syst 2018-06-06 [PMID: 29936182] (Human)		Human
Tong Y, Zhang G, Li Y et al. Corilagin inhibits breast cancer growth via reactive oxygen species-dependent apoptosis and autophagy J. Cell. Mol. Med. 2018-06-19 [PMID: 29923307] (Human)		Human
Lotfi P, Tse DY, Di Ronza A et al. Trehalose reduces retinal degeneration, neuroinflammation and storage burden caused by a lysosomal hydrolase deficiency. Autophagy. 2018-07-23 [PMID: 29916295] (WB, Mouse)	WB	Mouse
de Mattos Barbosa MG, de Andrade Silva BJ, Assis TQ et al. Autophagy Impairment Is Associated With Increased Inflammasome Activation and Reversal Reaction Development in Multibacillary Leprosy Front Immunol 2018-06-04 [PMID: 29915584] (ICC/IF, Human)	ICC/IF	Human
Kevin MK, Qin-Hua G, Jiji C, et al. Dendritic Distribution of Autophagosomes Underlies Pathway-Selective Induction of LTD SSRN Electronic Journal 2022-11-15 (WB)	WB
Li M, Pan B, Shi Y et al. Increased expression of CHOP and LC3B in newborn rats with bronchopulmonary dysplasia Int. J. Mol. Med. 2018-06-08 [PMID: 29901175] (Rat)		Rat
Chiang W C, Wei Y et al. High-Throughput Screens To Identify Autophagy Inducers That Function by Disrupting Beclin 1/Bcl-2 Binding. ACS Chem Biol 2018-08-17 [PMID: 29878747] (WB, Human)	WB	Human
Carr D, Lau R, Hnatykiw AD et al. cIAP2 Is an Independent Signaling and Survival Factor during Mammary Lactational Involution and Tumorigenesis J Mammary Gland Biol Neoplasia 2018-06-06 [PMID: 29876871] (Mouse)		Mouse
Li XR, Fu Q, Zhou M et al. Isoscoparins R and S, two new ent-clerodane diterpenoids from Isodon scoparius J Asian Nat Prod Res 2018-06-06 [PMID: 29873248] (WB, Human)	WB	Human
Stamatakou E, Zhu Y, Rubinsztein DC. Assessing Autophagic Activity and Aggregate Formation of Mutant Huntingtin in Mammalian Cells Methods Mol. Biol. 2018-06-02 [PMID: 29856012] (WB)	WB
Bhutia SK, Praharaj PP, Bhol CS et al. Monitoring and Measuring Mammalian Autophagy Methods Mol. Biol. 2018-06-01 [PMID: 29855817] (ICC/IF, Human)	ICC/IF	Human
Petersen Dennis R, Saba Laura M, Sayin Volkan I et al. Elevated Nrf-2 responses are insufficient to mitigate protein carbonylation in hepatospecific PTEN deletion mice. PloS One 2018-05-25 [PMID: 29799837] (WB, Mouse)	WB	Mouse
Gao Y Alzheimer disease: subcellular Abeta mechanisms and treatment strategies Thesis 2023-01-01
Li BX, Wang HB, Qiu MZ et al. Correction to: Novel smac mimetic APG-1387 elicits ovarian cancer cell killing through TNF-alpha, Ripoptosome and autophagy mediated cell death pathway J. Exp. Clin. Cancer Res. 2018-05-24 [PMID: 29793514] (WB)	WB
Hamlin AN, Chinnarasu S, Ding Y et al. Low density lipoprotein receptor-related protein-1 dysfunction synergizes with dietary cholesterol to accelerate steatohepatitis progression J. Biol. Chem. 2018-05-11 [PMID: 29752404] (Mouse)		Mouse
Ryabaya O, Prokofieva A, Khochenkov D et al. Inhibition of endoplasmic reticulum stress-induced autophagy sensitizes melanoma cells to temozolomide treatment Oncol. Rep. 2018-07-01 [PMID: 29749510] (WB, Human)	WB	Human
Gradzka S, Thomas O. S, et al. Inhibitor of apoptosis proteins are required for effective fusion of autophagosomes with lysosomes. Cell Death Dis 2018-05-01 [PMID: 29743550] (ICC/IF, Mouse)	ICC/IF	Mouse
Nobis S, Goichon A, Achamrah N et al. Alterations of proteome, mitochondrial dynamic and autophagy in the hypothalamus during activity-based anorexia Sci Rep 2018-05-08 [PMID: 29740148] (WB, Mouse)	WB	Mouse
Deshpande S, Abdollahi M, Wang M et al. Reduced Autophagy by a microRNA-mediated Signaling Cascade in Diabetes-induced Renal Glomerular Hypertrophy Sci Rep 2018-05-03 [PMID: 29725042] (WB)	WB
Wang Y, Zhao Z, Wei F et al. Combining autophagy-inducing peptides and brefeldin A delivered by perinuclear-localized mesoporous silica nanoparticles: a manipulation strategy for ER-phagy. Nanoscale 2018-04-11 [PMID: 29713715] (Human)		Human
Li N, Wang H, Jiang C, Zhang M. Renal ischemia/reperfusion-induced mitophagy protects against renal dysfunction via Drp1-dependent-pathway Exp. Cell Res. 2018-04-26 [PMID: 29704468] (WB)	WB
Sun X, Zhou L, Wang Y et al. Single-cell analyses reveal cannabidiol rewires tumor microenvironment via inhibiting alternative activation of macrophage and synergizes with anti-PD-1 in colon cancer Journal of Pharmaceutical Analysis 2023-04-01 (WB)	WB
Tamiya H, Urushihara N, Shizuma K et al. SHARPIN enhances ferroptosis in synovial sarcoma cells via NF-?B- and PRMT5-mediated PGC1? reduction bioRxiv 2023-04-17 (WB, Mouse)	WB	Mouse
Wen J, Li Y, Xiang Z et al. Lycorine Protects Motor Neurons Against TDP-43 Proteinopathy in Animal Models with Amyotrophic Lateral Sclerosis Available at SSRN 2023-03-29 (WB, Human)	WB	Human
Su Q, Zheng B, Wang CY et al. Oxidative Stress Induces Neuronal Apoptosis Through Suppressing Transcription Factor EB Phosphorylation at Ser467. Cell. Physiol. Biochem. 2018-04-19 [PMID: 29689560] (Human)		Human
Liao Y, Zhang P, Yuan B et al. Pravastatin Protects Against Avascular Necrosis of Femoral Head via Autophagy. Front Physiol 2018-04-09 [PMID: 29686621] (WB, Rat)	WB	Rat
Liu S, Li Y, Choi HMC et al. Lysosomal damage after spinal cord injury causes accumulation of RIPK1 and RIPK3 proteins and potentiation of necroptosis. Cell Death Dis 2018-04-23 [PMID: 29686269] (WB, Mouse)	WB	Mouse
FitzPatrick LM, Hawkins KE, Delhove JMKM et al. NF-kB Activity Initiates Human ESC-Derived Neural Progenitor Cell Differentiation by Inducing a Metabolic Maturation Program. Stem Cell Reports 2018-04-17 [PMID: 29681545] (WB, Human)	WB	Human
Wu Z, Zhao J, Qiu M et al. CRISPR/Cas9 mediated GFP knock-in at the MAP1LC3B locus in 293FT cells is better for bona fide monitoring cellular autophagy. Biotechnol J 2018-04-19 [PMID: 29673078] (Human)		Human
Coant N, Garcia-Barros M, Zhang Q et al. AKT as a key target for growth promoting functions of neutral ceramidase in colon cancer cells. Oncogene 2018-04-17 [PMID: 29662189] (Human)		Human
Walker A, Singh A, Tully E et al. Nrf2 signaling and autophagy are complementary in protecting breast cancer cells during glucose deprivation. Free Radic. Biol. Med. 2018-04-09 [PMID: 29649567] (WB, Human)	WB	Human
Lahuerta M, Aguado C, Sanchez-Martin P et al. Degradation of altered mitochondria by autophagy is impaired in Lafora disease. FEBS J. 2018-04-12 [PMID: 29645350] (WB, Human)	WB	Human
Kim S, Lee AJ, Yeo MK et al. Clinicopathological Profiling of LC3B, an Autophagy Marker, and ESRRA (Estrogen-related Receptor-alpha) in Muscle-invasive Bladder Cancer. Anticancer Res. 2018-04-01 [PMID: 29599373] (IF/IHC, Human)	IF/IHC	Human
Sanjurjo L, Aran G, Tellez E et al. CD5L Promotes M2 Macrophage Polarization through Autophagy-Mediated Upregulation of ID3 Front Immunol 2018-03-12 [PMID: 29593730] (WB, ICC/IF, Human)	WB, ICC/IF	Human
Li W, Li S, Li Y et al. Immunofluorescence Staining Protocols for Major Autophagy Proteins Including LC3, P62, and ULK1 in Mammalian Cells in Response to Normoxia and Hypoxia. Methods Mol. Biol. 2018-03-27 [PMID: 29582370] (ICC/IF)	ICC/IF
Manzoni C, Mamais A, Dihanich S et al. mTOR independent alteration in ULK1 Ser758 phosphorylation following chronic LRRK2 kinase inhibition. Biosci Rep 2018-04-26 [PMID: 29563162]
Peker N, Donipadi V et al. Loss of Parkin impairs mitochondrial function and leads to muscle atrophy. Am J Physiol Cell Physiol 2018-01-08 [PMID: 29561660] (WB, Mouse)	WB	Mouse
Ji J, Yu Y, Li Z, Chen M. XIAP Limits Autophagic Degradation of Sox2 and Is A Therapeutic Target in Nasopharyngeal Carcinoma Stem Cells. Theranostics. 2018-02-19 [PMID: 29556337] (ICC/IF, Human)	ICC/IF	Human
Khan MW, Layden BT, Chakrabarti P. Inhibition of mTOR complexes protects cancer cells from glutamine starvation induced cell death by restoring Akt stability. Biochim Biophys Acta Mol Basis Dis 2018-06-01 [PMID: 29555211]
Sachdev R, Kappes-Horn K, Paulsen L et al. Endoplasmic Reticulum Stress Induces Myostatin High Molecular Weight Aggregates and Impairs Mature Myostatin Secretion. Mol. Neurobiol. 2018-03-15 [PMID: 29546591] (Human)		Human
Hu Y, Sun Q, Hu Y et al. Corticosterone-Induced Lipogenesis Activation and Lipophagy Inhibition in Chicken Liver Are Alleviated by Maternal Betaine Supplementation. J. Nutr. 2018-03-01 [PMID: 29546310] (Avian)		Avian
Sha Z, Schnell HM, Ruoff K, Goldberg A. Rapid induction of p62 and GABARAPL1 upon proteasome inhibition promotes survival before autophagy activation. J. Cell Biol. 2018-03-13 [PMID: 29535191] (WB)	WB
Fitzwalter BE, Towers CG, Sullivan KD et al. Autophagy Inhibition Mediates Apoptosis Sensitization in Cancer Therapy by Relieving FOXO3a Turnover. Dev. Cell. 2018-03-12 [PMID: 29533771] (WB)	WB
Li BX, Wang HB, Qiu MZ et al. Novel smac mimetic APG-1387 elicits ovarian cancer cell killing through TNF-alpha, Ripoptosome and autophagy mediated cell death pathway. J. Exp. Clin. Cancer Res. 2018-03-12 [PMID: 29530056] (WB, Human)	WB	Human
Hong T, Ge Z, Meng R et al. Erythropoietin alleviates hepatic steatosis by activating SIRT1-mediated autophagy. Biochim Biophys Acta Mol Cell Biol Lipids 2018-06-01 [PMID: 29522896] (Mouse)		Mouse
Danyukova T, Ariunbat K, Thelen M et al. Loss of CLN7 results in depletion of soluble lysosomal proteins and impaired mTOR reactivation. Hum Mol Genet 2018-05-15 [PMID: 29514215]
Marrone L, Bus C, Schondorf D et al. Generation of iPSCs carrying a common LRRK2 risk allele for in vitro modeling of idiopathic Parkinson's disease. PLoS ONE. 2018-03-07 [PMID: 29513666] (WB, Human)	WB	Human
Stoughton WB, Li J, Balog-Alvarez C, Kornegay JN. Impaired Autophagy Correlates with Golden Retriever Muscular Dystrophy Phenotype. Muscle Nerve. 2018-03-07 [PMID: 29513363] (WB, Canine)	WB	Canine
Chen J, Zhang L, Zhou H et al. Inhibition of autophagy promotes cisplatin-induced apoptotic cell death through Atg5 and Beclin 1 in A549 human lung cancer cells. Mol Med Rep. 2018-03-06 [PMID: 29512762] (Human)		Human
Hsu CL, Lee EX, Gordon KL et al. MAP4K3 mediates amino acid-dependent regulation of autophagy via phosphorylation of TFEB. Nat Commun. 2018-03-05 [PMID: 29507340] (WB, Human)	WB	Human
Geng X, Ren Y, Wang F et al. Harmines inhibit cancer cell growth through coordinated activation of apoptosis and inhibition of autophagy. Biochem. Biophys. Res. Commun. 2018-03-25 [PMID: 29501493] (WB, Human)	WB	Human
Wang P, Jiang L, Zhou N et al. Resveratrol ameliorates autophagic flux to promote functional recovery in rats after spinal cord injury. Oncotarget 2018-02-02 [PMID: 29492205] (ICC/IF, Rat)	ICC/IF	Rat
Campbell GR, Bruckman RS, Herns SD et al. Induction of autophagy by PI3K/MTOR and PI3K/MTOR/BRD4 inhibitors suppresses HIV-1 replication. J. Biol. Chem. 2018-02-23 [PMID: 29475942] (WB)	WB
Delorme-Axford E, Abernathy E, Lennemann NJ et al. The exoribonuclease Xrn1 is a post-transcriptional negative regulator of autophagy. Autophagy 2018-03-21 [PMID: 29465287]
Li YL, Cai WF, Wang L et al. Identification of the Functional Autophagy-Regulatory Domain in HCLS1-Associated Protein X-1 That Resists Against Oxidative Stress. DNA Cell Biol 2018-05-01 [PMID: 29461873] (Human)		Human
Zhu, Y, Shan, X Et al. Pharmacological Inhibition of O-GlcNAcase Enhances Autophagy in Brain through an mTOR-Independent Pathway. ACS Chem Neurosci 2018-06-20 [PMID: 29460617] (ICC/IF, Mouse)	ICC/IF	Mouse
Panda PK, Naik PP, Praharaj PP, Meher BR. Abrus agglutinin stimulates BMP-2-dependent differentiation through autophagic degradation of b-catenin in colon cancer stem cells. Mol. Carcinog. 2018-02-19 [PMID: 29457276] (Human)		Human
Zheng Z, Zhang L, Qu Y, Xiao G. Mesenchymal stem cells protect against hypoxia-ischemia brain damage by enhancing autophagy through BDNF/mTOR signaling pathway. Stem Cells. 2018-02-16 [PMID: 29451335] (Rat)		Rat
Lei Z, Deng M, Yi Z, Sun Q. cGAS-mediated autophagy protects the liver from ischemia/reperfusion injury independent of STING. Am. J. Physiol. Gastrointest. Liver Physiol. 2018-02-15 [PMID: 29446653] (Mouse)		Mouse
Agod Z, Pazmandi K, Bencze D, Vereb G. Signaling Lymphocyte Activation Molecule Family 5 Enhances Autophagy and Fine-Tunes Cytokine Response in Monocyte-Derived Dendritic CellsviaStabilization of Interferon Regulatory Factor 8. Front Immunol. 2018-01-26 [PMID: 29434592] (WB, Human)	WB	Human
Liu J, Liu W, Lu Y, Tian H. Piperlongumine restores the balance of autophagy and apoptosis by increasing BCL2 phosphorylation in rotenone-induced Parkinson disease models. Autophagy. 2018-02-13 [PMID: 29433359] (Mouse)		Mouse
Puddighinu Giovanni, D'amario Domenico, Foglio Eleonora et al. Molecular mechanisms of cardioprotective effects mediated by transplanted cardiac ckit+ cells through the activation of an inflammatory hypoxia-dependent reparative response. Oncotarget 2018-01-01 [PMID: 29416668] (ICC/IF, Mouse)	ICC/IF	Mouse
Minamoto T, Nakayama K, Nakamura K et al. Loss of beclin 1 expression in ovarian cancer: A potential biomarker for predicting unfavorable outcomes Oncology Letters 2017-11-09 [PMID: 29399172] (IF/IHC, Human)	IF/IHC	Human
Liuzzi JP, Narayanan V, Doan H, Yoo C. Effect of zinc intake on hepatic autophagy during acute alcohol intoxication. Biometals. 2018-02-01 [PMID: 29392448] (WB, Mouse)	WB	Mouse
Zhou Z, Ribas V, Rajbhandari P, Drew BG. Estrogen receptor alpha protects pancreatic beta cells from apoptosis by preserving mitochondrial function and suppressing endoplasmic reticulum stress. J. Biol. Chem. 2018-01-29 [PMID: 29378845] (WB, Mouse)	WB	Mouse
Sun T, Jiao L, Wang Y et al. SIRT1 induces epithelial-mesenchymal transition by promoting autophagic degradation of E-cadherin in melanoma cells Cell Death Dis 2018-01-26 [PMID: 29374154] (WB, Human)	WB	Human
Inoue N, Ogura S, Kasai A et al. Knockdown of the mitochondria-localized protein p13 protects against experimental parkinsonism EMBO Rep. 2018-01-25 [PMID: 29371327] (WB, Human)	WB	Human
Katreddy RR, Bollu LR, Su F et al. Targeted reduction of the EGFR protein, but not inhibition of its kinase activity, induces mitophagy and death of cancer cells through activation of mTORC2 and Akt Oncogenesis 2018-01-23 [PMID: 29358623] (WB, Human)	WB	Human
Goiran T, Duplan E, Rouland L et al. Nuclear p53-mediated repression of autophagy involves PINK1 transcriptional down-regulation Cell Death Differ. 2018-05-01 [PMID: 29352272] (WB, Mouse)	WB	Mouse
Miranda AM, Lasiecka ZM, Xu Y et al. Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures. Nat Commun 2018-01-18 [PMID: 29348617] (WB, Mouse)	WB	Mouse
Sil S, Periyasamy P, Guo ML et al. Morphine-Mediated Brain Region-Specific Astrocytosis Involves the ER Stress-Autophagy Axis Mol. Neurobiol. 2018 Jan 17 [PMID: 29344928] (Primate)		Primate
Sil S, Periyasamy P, Guo ML et al. Morphine-Mediated Brain Region-Specific Astrocytosis Involves the ER Stress-Autophagy Axis Molecular Neurobiology 2018-08-01 [PMID: 29344928] (In Vivo)	In Vivo
Wang JP, Chi RF, Wang K, Ma T. Oxidative stress impairs myocyte autophagy, resulting in myocyte hypertrophy. Exp. Physiol. 2018-01-12 [PMID: 29327381] (WB, Rat)	WB	Rat
Mukhopadhyay R, Venkatadri R, Katsnelson J et al. Digitoxin Suppresses Human Cytomegalovirus Replication via Na+, K+/ATPase a1 Subunit-Dependent AMP-Activated Protein Kinase and Autophagy Activation J. Virol. 2018-03-15 [PMID: 29321306] (WB, Human)	WB	Human
Hui kY, Fernandez-Hernandez H, Hu J et al. Functional variants in the LRRk2 gene confer shared effects on risk for Crohn's disease and Parkinson's disease. Sci Transl Med. 2018-01-10 [PMID: 29321258] (WB, Human)	WB	Human
Sebastiani A, Golz C, Sebastiani PG et al. Sequestosome 1 Deficiency Delays, but Does Not Prevent Brain Damage Formation Following Acute Brain Injury in Adult Mice Front Neurosci 2017-12-19 [PMID: 29311767] (WB, Mouse)	WB	Mouse
Toubai T, Rossi C et al. IAPs protect host target tissues from graft-versus-host disease in mice. Blood Adv 2017-08-22 [PMID: 29296793] (FLOW, Mouse)	FLOW	Mouse
Greiner GF, Conraux C, Collard M, Picart P. [Value of pendular rotational methods in the study of vestibular reequilibration]. Rev Otoneuroophtalmol 2018-01-01 [PMID: 29290944] (WB, Human)	WB	Human
Falcon B, Noad J, McMahon H et al. Galectin-8-mediated selective autophagy protects against seeded tau aggregation. J. Biol. Chem. 2017-12-27 [PMID: 29282296] (WB)	WB
Evans T, Kok WL, Cowan K et al. Accumulation of beta-synuclein in cortical neurons is associated with autophagy attenuation in the brains of dementia with Lewy body patients. Brain Res. 2017-12-23 [PMID: 29278715] (Human)		Human
Shen YQ, Guerra-Librero A, Fernandez-Gil BI et al. Combination of melatonin and rapamycin for head and neck cancer therapy: Suppression of AKT/mTOR pathway activation, and activation of mitophagy and apoptosis via mitochondrial function regulation. J. Pineal Res. 2017-12-16 [PMID: 29247557] (Mouse)		Mouse
Panda PK, Naik PP, Meher BR, Das DN. PUMA dependent mitophagy by Abrus agglutinin contributes to apoptosis through ceramide generation. Biochim Biophys Acta 1905-07-09 [PMID: 29229477] (Human)		Human
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Naik PP, Mukhopadhyay S, Panda PK et al. Autophagy regulates cisplatin-induced stemness and chemoresistance via the upregulation of CD44, ABCB1 and ADAM17 in oral squamous cell carcinoma Cell Prolif. 2017-11-23 [PMID: 29171106] (ICC/IF, Human)	ICC/IF	Human
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Masuelli L, Granato M, Benvenuto M et al. Chloroquine supplementation increases the cytotoxic effect of curcumin against Her2/neu overexpressing breast cancer cells in vitro and in vivo in nude mice while counteracts it in immune competent mice Oncoimmunology. 2017-07-30 [PMID: 29147611] (WB, Mouse)	WB	Mouse
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Jabir MS, Sulaiman GM, Taqi ZJ, Li D. Iraqi propolis increases degradation of IL-1beta and NLRC4 by autophagy following Pseudomonas aeruginosa infection. Microbes Infect 2018-02-01 [PMID: 29104144] (WB)	WB
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Rostami J, Holmqvist S, Lindstrom V et al. Human astrocytes transfer aggregated alpha-synuclein via tunneling nanotubes J. Neurosci. 2017-10-31 [PMID: 29089438] (Human)		Human
Zowalaty AEE, Ye X Seipin deficiency leads to defective parturition in mice Biol Reprod. 2017-08-13 [PMID: 29088395] (IF/IHC, Mouse)	IF/IHC	Mouse
Luningschror P, Binotti B, Dombert B et al. Plekhg5-regulated autophagy of synaptic vesicles reveals a pathogenic mechanism in motoneuron disease Nat Commun. 2017-10-30 [PMID: 29084947] (WB, Mouse)	WB	Mouse
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Li X, Wu XQ, Deng R et al. CaMKII-mediated Beclin 1 phosphorylation regulates autophagy that promotes degradation of Id and neuroblastoma cell differentiation. Nat Commun. 2017-10-27 [PMID: 29079782] (WB, Human)	WB	Human
Qian Q, Zhang Z, Orwig A et al. S-Nitrosoglutathione Reductase Dysfunction Contributes to Obesity-Associated Hepatic Insulin Resistance via Regulating Autophagy Diabetes 2017-10-26 [PMID: 29074597] (WB, Mouse)	WB	Mouse
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Shabaninia M, Tourchi A, Di Carlo H, Gearhart J. Autophagy, Apoptosis and Cell Proliferation in Exstrophy-Epispadias Complex. Urology. 2017-10-03 [PMID: 28986224] (Human)		Human
Yang C, Cai CZ, Song JX et al. NRBF2 is involved in the autophagic degradation process of APP-CTFs in Alzheimer disease models. Autophagy. 2017-10-05 [PMID: 28980867] (Mouse)		Mouse
Jiao L, Zhang HL, Li DD et al. Regulation of Glycolytic Metabolism by Autophagy in Liver Cancer Involves Selective Autophagic Degradation of HK2 (hexokinase 2). Autophagy. 2017-10-05 [PMID: 28980855] (Human)		Human
Bricard G, Cadassou O, Cassagnes LE et al. The cytosolic 5'-nucleotidase cN-II lowers the adaptability to glucose deprivation in human breast cancer cells Oncotarget. 2017-09-14 [PMID: 28978040] (WB, Human)	WB	Human
Boselli M, Lee BH, Robert J et al. An inhibitor of the proteasomal deubiquitinating enzyme USP14 induces tau elimination in cultured neurons. J. Biol. Chem. 2017-09-26 [PMID: 28972160] (WB)	WB
Fakouri NB, Durhuus JA, Regnell CE et al. Rev1 contributes to proper mitochondrial function via the PARP-NAD(+)-SIRT1-PGC1a axis. Sci Rep. 2017-10-02 [PMID: 28970491] (WB, Mouse)	WB	Mouse
An Z, Qiao F, Lu Q et al. Interleukin-6 downregulated vascular smooth muscle cell contractile proteins via ATG4B-mediated autophagy in thoracic aortic dissection. Heart Vessels. 2017-09-30 [PMID: 28965202] (Human)		Human
Granato M, Gilardini Montani MS, Romeo MA et al. Metformin triggers apoptosis in PEL cells and alters bortezomib-induced Unfolded Protein Response increasing its cytotoxicity and inhibiting KSHV lytic cycle activation. Cell. Signal. 2017-12-01 [PMID: 28964970] (WB)	WB
Xue R, Jiang J, Dong B et al. DJ-1 activates autophagy in the repression of cardiac hypertrophy Arch. Biochem. Biophys. 2017-09-21 [PMID: 28941803] (WB, Rat)	WB	Rat
Wei H, Cui R, Bahr J et al. miR-130a deregulates PTEN and stimulates tumor growth Cancer Res. 2017-09-21 [PMID: 28935812] (WB, Mouse)	WB	Mouse
Zhang G, Liu Z, Ding H et al. Tumor induces muscle wasting in mice through releasing extracellular Hsp70 and Hsp90 Nat Commun 2017-09-19 [PMID: 28928431] (WB, Mouse)	WB	Mouse
Park Tae Kwann, Lee Si Hyung, Choi Jun Sub et al. Adeno-Associated Viral Vector-Mediated mTOR Inhibition by Short Hairpin RNA Suppresses Laser-Induced Choroidal Neovascularization. Molecular Therapy. Nucleic Acids 2017-09-15 [PMID: 28918027] (IF/IHC, Mouse)	IF/IHC	Mouse
Feng Y, Madungwe NB, da Cruz Junho CV, Bopassa JC. Activation of G protein-coupled oestrogen receptor 1 at the onset of reperfusion protects the myocardium against ischemia/reperfusion injury by reducing mitochondrial dysfunction and mitophagy. Br. J. Pharmacol. 2017-12-01 [PMID: 28906548] (WB, Rat)	WB	Rat
Ndoye A, Budina-Kolomets A, Kugel CH et al. ATG5 mediates a positive feedback loop between Wnt signaling and autophagy in melanoma Cancer Res. 2017-09-08 [PMID: 28887323] (Mouse)		Mouse
Wang X, Zhang X, Chu ESH et al. Defective lysosomal clearance of autophagosomes and its clinical implications in nonalcoholic steatohepatitis FASEB J. 2017-08-25 [PMID: 28842428] (Mouse)		Mouse
Zhang M, Tao W et al. Mst-1 deficiency promotes post-traumatic spinal motor neuron survival via enhancement of autophagy flux. J Neurochem 2017-01-10 [PMID: 28833175] (WB, Mouse)	WB	Mouse
Ramirez-Martinez A, Cenik BK, Bezprozvannaya S et al. KLHL41 stabilizes skeletal muscle sarcomeres by nonproteolytic ubiquitination Elife 2017-08-09 [PMID: 28826497] (Mouse)		Mouse
Zhang X, Wu WK, Xu W et al. C-X-C Motif Chemokine 10 Impairs Autophagy and Autolysosome Formation in Non-alcoholic Steatohepatitis Theranostics 2017 Aug 21 [PMID: 28824718] (WB, Human)	WB	Human
Rocchi A, Yamamoto S, Ting T et al. A Becn1 mutation mediates hyperactive autophagic sequestration of amyloid oligomers and improved cognition in Alzheimer's disease. PLoS Genet 2017-08-14 [PMID: 28806762] (WB, Mouse)	WB	Mouse
Zhao XL, Lin Y, Jiang J et al. HMGB1 released by autophagic cancer-associated fibroblasts maintains the stemness of luminal breast cancer cells J. Pathol. 2017-08-12 [PMID: 28802057] (Human)		Human
Dai X, Zeng J, Yan X et al. Sitagliptin-mediated preservation of endothelial progenitor cell function via augmenting autophagy enhances ischaemic angiogenesis in diabetes J. Cell. Mol. Med. 2017-08-10 [PMID: 28799229] (WB, Mouse)	WB	Mouse
Mishra P, Dauphinee AN, Ward C et al. Discovery of pan autophagy inhibitors through a high-throughput screen highlights macroautophagy as an evolutionarily conserved process across 3 eukaryotic kingdoms Autophagy 2017-08-09 [PMID: 28792845] (WB, Human)	WB	Human
Zhan X The effect of choline supplement and miR-29b-3p in porcine ovarian follicular development Thesis 2023-01-01 (WB, Porcine)	WB	Porcine
Rogers RS, Tungtur S, Tanaka T et al. Impaired Mitophagy Plays a Role in Denervation of Neuromuscular Junctions in ALS Mice Front Neurosci 2017-09-11 [PMID: 28890682] (IF/IHC, Mouse)	IF/IHC	Mouse
Seidah N, Sachan V, Devehat M et al. PCSK7: a Novel Regulator of Apolipoprotein B and a Potential Target Against Non-Alcoholic Fatty Liver Disease Research Square 2023-03-24 (WB)	WB
Zhang X, Wu WK, Xu W et al. CXC Motif Chemokine 10 Impairs Autophagy and Autolysosome Formation in Non-alcoholic Steatohepatitis THERANOSTICS 2017 Aug 21 [PMID: 28824718] (WB, Human)	WB	Human
Naia L, Shimozawa M, Bereczki E et al. Early mitochondrial dysfunction proceeds neuroinflammation, synaptic alteration, and autophagy impairment in hippocampus ofAppknock-in Alzheimer mouse models bioRxiv 2023-03-13 (IHC-P)	IHC-P
Lin TW, Chen MT, Lin LT et al. TDP-43/HDAC6 axis promoted tumor progression and regulated nutrient deprivation-induced autophagy in glioblastoma Oncotarget 2017-08-22 [PMID: 28915616] (WB, Human)	WB	Human
Rudnick ND, Griffey CJ, Guarnieri P et al. Distinct roles for motor neuron autophagy early and late in the SOD1(G93A) mouse model of ALS Proc. Natl. Acad. Sci. U.S.A. 2017-09-26 [PMID: 28904095] (Mouse)		Mouse
Bartolomeo R, Cinque L, De Leonibus C mTORC1 hyperactivation arrests bone growth in lysosomal storage disorders by suppressing autophagy. J Clin Invest. 2017-10-02 [PMID: 28872463] (ICC/IF, Mouse)	ICC/IF	Mouse
Szabo DJ, Nagymihaly R, Vereb Z et al. Ex vivo 3D human corneal stroma model for Schnyder corneal dystrophy - role of autophagy in its pathogenesis and resolution. Histol Histopathol 2018-05-01 [PMID: 28872183] (Human)		Human
Sparrer KMJ, Gableske S, Zurenski MA et al. TRIM23 mediates virus-induced autophagy via activation of TBK1 Nat Microbiol 2017-09-04 [PMID: 28871090] (B/N)	B/N
Kim SW, Ehrman J, Ahn MR et al. Shear stress induces noncanonical autophagy in intestinal epithelial monolayers Mol. Biol. Cell 2017-11-01 [PMID: 28855375] (ICC/IF, Human)	ICC/IF	Human
Liu H, Javaheri A, Godar RJ et al. Intermittent Fasting Preserves Beta-Cell Mass in Obesity-induced Diabetes via the Autophagy-Lysosome Pathway Autophagy 2017-08-30 [PMID: 28853981] (Mouse)		Mouse
Lee A, Rayner SL, Gwee SSL et al. Pathogenic mutation in the ALS/FTD gene, CCNF, causes elevated Lys48-linked ubiquitylation and defective autophagy. Cell Mol Life Sci 2018-01-01 [PMID: 28852778] (Human)		Human
Tang Z, Takahashi Y, Chen C et al. Atg2A/B deficiency switches cytoprotective autophagy to non-canonical caspase-8 activation and apoptosis Cell Death Differ. 2017-08-10 [PMID: 28800131] (WB, Human)	WB	Human
Lee KH, Lee S, Lee HJ et al. Amyloid B1-42 (AB1-42) Induces the CDK2-Mediated Phosphorylation of Tau through the Activation of the mTORC1 Signaling Pathway While Promoting Neuronal Cell Death Front. Mol. Neurosci. 2017-07-24 [PMID: 28790888] (ICC/IF, Human)	ICC/IF	Human
Wang H, Wang J, Yang J et al. Guanine nucleotide exchange factor -H1 promotes inflammatory cytokine production and intracellular mycobacterial elimination in macrophages Cell Cycle 2017-08-07 [PMID: 28783414] (Bacteria)		Bacteria
Stewart SE, Menzies SA, Popa SJ et al. A genome-wide CRISPR screen reconciles the role of N-linked glycosylation in galectin-3 transport to the cell surface. J. Cell. Sci. 2017-10-01 [PMID: 28775154] (WB, Human)	WB	Human
Vithal T. Investigating the function of CLU in Alzheimer's Disease in in vitro and in vivo models. Thesis. 1905-07-08 (WB, Human)	WB	Human
Xie Yangchun, Zhu Shan, Zhong Meizuo et al. Inhibition of Aurora Kinase A Induces Necroptosis in Pancreatic Carcinoma. Gastroenterology 2017-07-02 [PMID: 28764929] (WB, Human)	WB	Human
Cha-Molstad H, Yu JE, Feng Z et al. p62/SQSTM1/Sequestosome-1 is an N-recognin of the N-end rule pathway which modulates autophagosome biogenesis Nat Commun 2017-07-24 [PMID: 28740232] (WB, Human)	WB	Human
Du C, Ren Y, Yao F et al. Sphingosine kinase 1 protects renal tubular epithelial cells from renal fibrosis via induction of autophagy Int. J. Biochem. Cell Biol. 2017-07-18 [PMID: 28733250] (Mouse)		Mouse
Shen L, Yang Y, Ou T et al. Dietary PUFAs attenuate NLRP3 inflammasome activation via enhancing macrophage autophagy J. Lipid Res. 2017-07-20 [PMID: 28729463] (WB, Mouse)	WB	Mouse
Teyssou E, Chartier L, Amador MD et al. Novel UBQLN2 mutations linked to amyotrophic lateral sclerosis and atypical hereditary spastic paraplegia phenotype through defective HSP70-mediated proteolysis Neurobiology of Aging 2017-10-01 [PMID: 28716533] (WB, B/N)	WB, B/N
Willy JA, Young SK, Mosley AL et al. Function of Inhibitor of Brutons Tyrosine Kinase Isoform alpha (IBTKalpha) in Nonalcoholic Steatohepatitis links Autophagy and the Unfolded Protein Response J. Biol. Chem. 2017-07-14 [PMID: 28710282] (WB, Human)	WB	Human
Li L, Zviti R, Ha C et al. Forkhead Box O3 (FoxO3) Regulates Kidney Tubular Autophagy Following Urinary Tract Obstruction J. Biol. Chem. 2017-07-13 [PMID: 28705935] (WB)	WB
Lee H, Jung Y, Choi G et al. BNIP3 induction by hypoxia stimulates FASN-dependent free fatty acid production enhancing therapeutic potential of umbilical cord blood-derived human mesenchymal stem cells Redox Biol 2017-07-04 [PMID: 28704726] (ICC/IF, Human)	ICC/IF	Human
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Mathai BJ, Meijer AH, Simonsen A. Studying Autophagy in Zebrafish. Cells 2017-07-09 [PMID: 28698482] (ICC/IF, Zebrafish)	ICC/IF	Zebrafish
Popp L, Gomez E, Orji W et al. TFEB-mediated activation of the lysosome-autophagy system affects the transduction efficiency of adeno-associated virus 2 Virology 2017-07-05 [PMID: 28688268] (WB)	WB
Chen L, Zhao L, Samanta A et al. STAT3 balances myocyte hypertrophy vis-A-vis autophagy in response to Angiotensin II by modulating the AMPK alpha/mTOR axis PLoS One. 2017-07-06 [PMID: 28686615] (WB, Human)	WB	Human
Bricard G, Cadassou O, Cassagnes LE et al. The cytosolic 5'-nucleotidase cN-II lowers the adaptability to glucose deprivation in human breast cancer cells Oncotarget 2017-06-27 [PMID: 28679870] (WB, Human)	WB	Human
Liu C, Choi H, Johnson ZI et al. Lack of evidence for involvement of TonEBP and hyperosmotic stimulus in induction of autophagy in the nucleus pulposus Sci Rep 2017-07-03 [PMID: 28674405] (ICC/IF, Rat)	ICC/IF	Rat
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Zhou X, Yue GG, Chan AM et al. Eriocalyxin B, a novel autophagy inducer, exerts anti-tumor activity through the suppression of Akt/mTOR/p70S6K signaling pathway in breast cancer Biochem. Pharmacol. 2017-06-30 [PMID: 28669564] (IHC-P, Human)	IHC-P	Human
Ha S, Jeong SH, Yi K et al. Phosphorylation of p62 by AMP-activated protein kinase mediates autophagic cell death in adult hippocampal neural stem cells J. Biol. Chem. 2017-06-27 [PMID: 28655770] (Human, Rat)		Human, Rat
Mohanty S, Kumar A, Das P et al. Multi-targeted therapy of everolimus in Kaposi's sarcoma associated herpes virus infected primary effusion lymphoma Apoptosis 2017-06-26 [PMID: 28653223] (Human)		Human
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Kim Y, Jeong EI, Nah J et al. Pimozide reduces toxic forms of tau in TauC3 mice via AMPK-mediated autophagy. J. Neurochem. 2017-06-20 [PMID: 28632947] (WB)	WB
Liu YQ, Jia MQ, Xie ZH et al. Arrestins contribute to amyloid beta-induced cell death via modulation of autophagy and the alpha7nAch receptor in SH-SY5Y cells. Sci Rep. 2017-06-13 [PMID: 28611418] (WB, Human)	WB	Human
Bischoff FC, Werner A, John D et al. Identification and Functional Characterization of Hypoxia-Induced Endoplasmic Reticulum Stress Regulating lncRNA (HypERlnc) in Pericytes. Circ. Res. 2017-08-04 [PMID: 28611075] (Human)		Human
Beard H, Hassiotis S, Gai WP et al. Axonal dystrophy in the brain of mice with Sanfilippo syndrome. Exp. Neurol. 2017-06-08 [PMID: 28601604] (Mouse)		Mouse
Ka M, Smith AL, Kim WY. MTOR controls genesis and autophagy of GABAergic interneurons during brain development. Autophagy. 2017-06-09 [PMID: 28598226] (WB, Mouse)	WB	Mouse
Sergin I, Evans TD, Zhang X et al. Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis. Nat Commun. 2017-06-07 [PMID: 28589926] (WB, Mouse)	WB	Mouse
Pan H, Yan Y, Liu C, Finkel, T. The role of ZKSCAN3 in the transcriptional regulation of autophagy. Autophagy. 2017-06-05 [PMID: 28581889] (WB, Mouse)	WB	Mouse
Shao BZ, Ke P, Xu ZQ et al. Autophagy Plays an Important Role in Anti-inflammatory Mechanisms Stimulated by Alpha7 Nicotinic Acetylcholine Receptor. Front Immunol 2017-05-31 [PMID: 28559895] (ICC/IF, IB, Mouse)	ICC/IF, IB	Mouse
Chen C, Lu Y, Siu HM et al. Identification of Novel Vacuolin-1 Analogues as Autophagy Inhibitors by Virtual Drug Screening and Chemical Synthesis. Molecules. 2017-05-27 [PMID: 28555021] (WB, Human)	WB	Human
Tsai TH, Chen E, Li L et al. The Constitutive Lipid Droplet Protein Plin2 Regulates Autophagy in Liver. Autophagy 2017-05-26 [PMID: 28548876] (WB, Mouse)	WB	Mouse
Salcher S, Hermann M, Kiechl-Kohlendorfer U, Ausserlechner MJ, Obexer P. C10ORF10/DEPP-mediated ROS accumulation is a critical modulator of FOXO3-induced autophagy. Mol Cancer. 2017-05-25 [PMID: 28545464] (IB, Human)	IB	Human
Brinkmann C, Przyklenk A, Metten A et al. Influence of endurance training on skeletal muscle mitophagy regulatory proteins in type 2 diabetic men. Endocr. Res. 2017-05-24 [PMID: 28537848] (WB, Human)	WB	Human
Nitschke F, Sullivan MA, Wang P et al. Abnormal glycogen chain length pattern, not hyperphosphorylation, is critical in Lafora disease. EMBO Mol Med 2017-05-23 [PMID: 28536304]
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Wang L, Gundelach JH, Bram RJ. Cycloheximide promotes paraptosis induced by inhibition of cyclophilins in glioblastoma multiforme. Cell Death Dis 2017-05-18 [PMID: 28518150]
Serfass JM, Takahashi Y, Zhou Z et al. Endophilin B2 facilitates endosome maturation in response to growth factor stimulation, autophagy induction, and influenza A virus infection J. Biol. Chem. 2017-06-16 [PMID: 28455444] (WB, Human)	WB	Human
Wu DJ, Adamopoulos IE. Loss of WDFY3 ameliorates severity of serum transfer-induced arthritis independently of autophagy. Cell Immunol 2017-04-22 [PMID: 28449847]
Ashkenazi A, Bento CF, Ricketts T et al. Polyglutamine tracts regulate beclin 1-dependent autophagy. Nature. 2017-04-26 [PMID: 28445460] (WB, Mouse)	WB	Mouse
D'Eliseo D, Di Renzo L, Santoni A, Velotti F. Docosahexaenoic acid (DHA) promotes immunogenic apoptosis in human multiple myeloma cells, induces autophagy and inhibits STAT3 in both tumor and dendritic cells. Genes Cancer. 2017-01-01 [PMID: 28435516] (WB, Human)	WB	Human
Tawo R, Pokrzywa W, Kevei e et al. The Ubiquitin Ligase CHIP Integrates Proteostasis and Aging by Regulation of Insulin Receptor Turnover. Cell. 2017-04-20 [PMID: 28431247] (Chemotaxis, Human)	Chemotaxis	Human
Wang J, Wang R, Wang H et al. Glucocorticoids Suppress Antimicrobial Autophagy and Nitric Oxide Production and Facilitate Mycobacterial Survival in Macrophages. Sci Rep 2017-04-20 [PMID: 28428627] (WB, Mouse)	WB	Mouse
Zielniok K, Sobolewska A, Gajewska M. Mechanisms of autophagy induction by sex steroids in bovine mammary epithelial cells. J. Mol. Endocrinol. 2017-04-20 [PMID: 28428343]
Li J, Song P, Zhu L et al. Synthetic lethality of glutaminolysis inhibition, autophagy inactivation and asparagine depletion in colon cancer Oncotarget 2017-06-27 [PMID: 28424408] (WB, Human)	WB	Human
Wang J, Wang R, Yang J et al. Glucocorticoids differentially regulate the innate immune responses of TLR4 and the cytosolic DNA sensing pathway. Int. Immunopharmacol. 2017-04-14 [PMID: 28415024] (WB)	WB
Peraro L, Zou Z, Makwana KM et al. Diversity-Oriented Stapling Yields Intrinsically Cell-Penetrant Inducers of Autophagy J Am Chem Soc. 2017-06-14 [PMID: 28414223] (Human)		Human
Wu M, Liu X, Chi X et al. Mitophagy in Refractory Temporal Lobe Epilepsy Patients with Hippocampal Sclerosis. Cell Mol Neurobiol 2018-03-01 [PMID: 28405902] (Human)		Human
Liu X, Li Y, Wang X, Xing R The BEACH-containing protein WDR81 coordinates p62 and LC3C to promote aggrephagy J Cell Biol. 2017-04-30 [PMID: 28404643] (WB)	WB
Ullah I, Ritchie ND, Evans TJ. The interrelationship between phagocytosis, autophagy and formation of neutrophil extracellular traps following infection of human neutrophils by Streptococcus pneumoniae. Innate Immun. 2017-01-01 [PMID: 28399692] (ICC/IF, Bacteria)	ICC/IF	Bacteria
Riaz Ahmed KB, Kanduluru AK, Feng L et al. Antitumor agent 25-epi Ritterostatin GN1N induces endoplasmic reticulum stress and autophagy mediated cell death in melanoma cells. Int. J. Oncol. 2017-05-01 [PMID: 28393217] (WB, Human)	WB	Human
Sathyanarayan A, Mashek MT, Mashek DG. ATGL Promotes Autophagy/Lipophagy via SIRT1 to Control Hepatic Lipid Droplet Catabolism. Cell Rep. 2017-04-04 [PMID: 28380348] (IB, WB, Mouse)	IB, WB	Mouse
Yin Y, Li E, Sun G et al. Effects of DHA on Hippocampal Autophagy and Lysosome Function After Traumatic Brain Injury. Mol. Neurobiol. 2017-04-01 [PMID: 28365875]
Lee WK, Probst S, Santoyo-Sanchez MP et al. Initial autophagic protection switches to disruption of autophagic flux by lysosomal instability during cadmium stress accrual in renal NRK-52E cells. Arch Toxicol 2017-03-20 [PMID: 28321485]
Matos L, Gouveia AM, Almeida H. Resveratrol Attenuates Copper-Induced Senescence by Improving Cellular Proteostasis. Oxid Med Cell Longev. 2017-03-10 [PMID: 28280523] (WB, Human)	WB	Human
Huang W, Ao P, Li J et al. Autophagy protects advanced glycation end product-induced apoptosis and. BioMed Research International. 2017-01-16 [PMID: 28265573] (WB, Rat)	WB	Rat
Inoue T, Tanaka M, Masuda S et al. Omega-3 polyunsaturated fatty acids suppress the inflammatory responses of lipopolysaccharide-stimulated mouse microglia by activating SIRT1 pathways. Biochim. Biophys. Acta. 2017-02-22 [PMID: 28254441]
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Liu Y, Wang X, Wang J et al. Graphene Oxide Attenuates the Cytotoxicity and Mutagenicity of PCB 52 via Activation of Genuine Autophagy. Environ. Sci. Technol. 2016-02-23 [PMID: 26876502] (WB, ICC/IF)	WB, ICC/IF
Liu Y, Takahashi Y, Desai N et al. Bif-1 deficiency impairs lipid homeostasis and causes obesity accompanied by insulin resistance. Sci Rep 2016-02-09 [PMID: 26857140] (ELISA)	ELISA
Wu X, Fleming A, Ricketts T et al. Autophagy regulates Notch degradation and modulates stem cell development and neurogenesis. Nat Commun. 2016-02-03 [PMID: 26837467] (WB, Human)	WB	Human
Gentry EG, Henderson BW, Arrant AE et al. Rho Kinase Inhibition as a Therapeutic for Progressive Supranuclear Palsy and Corticobasal Degeneration. J Neurosci 2016-01-27 [PMID: 26818518] (WB)	WB
Button RW, Vincent JH, Strang CJ, Luo S Dual PI-3 kinase/mTOR inhibition impairs autophagy flux and induces cell death independent of apoptosis and necroptosis. Oncotarget 2016-02-02 [PMID: 26814436] (ICC/IF)	ICC/IF
Wei J, Long L, Yang K et al. Autophagy enforces functional integrity of regulatory T cells by coupling environmental cues and metabolic homeostasis. Nat Immunol 2016-03-01 [PMID: 26808230]
Urtasun R, Elizalde M, Azkona M et al. Splicing regulator SLU7 preserves survival of hepatocellular carcinoma cells and other solid tumors via oncogenic miR-17-92 cluster expression. Oncogene 2016-09-08 [PMID: 26804174]
Tian T, Sun Y, Wu H et al. Acupuncture promotes mTOR-independent autophagic clearance of aggregation-prone proteins in mouse brain. Sci Rep. 2016-01-21 [PMID: 26792101] (WB, Mouse) Details: LC3 antibody was used for WB analysis of lysates from the substantia nigra par compacta /SNpc of the brain from control group (Saline), the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine/MPTP-treated PD mice, the acupuncture group stimulated at the acupoint GB34, the sham acupuncture group stimulated at the control point, and the rapamycin treatment group (Figure 3a).	WB	Mouse
Yang L, Licastro D, Cava E et al. Long-Term Calorie Restriction Enhances Cellular Quality-Control Processes in Human Skeletal Muscle. Cell Rep. 2016-01-26 [PMID: 26774472] (WB, Human) Details: LC3B/MAP1LC3B antibody was used for Western Blot analysis of human skeletal muscle tissues from Individuals on Western diet/WD or calorie restriction/CR Diet (Figure 3).	WB	Human
Bourdenx M, Daniel J, Genin E et al. Nanoparticles restore lysosomal acidification defects: Implications for Parkinson and other lysosomal-related diseases Autophagy. 2016-01-12 [PMID: 26761717] (WB, Human)	WB	Human
Mukherjee R, Chakrabarti O. Ubiquitin mediated regulation of the E3 ligase GP78 by Mahogunin in trans affects mitochondrial homeostasis. J. Cell. Sci. 2016-01-07 [PMID: 26743086] (WB, Human)	WB	Human
Kraft LJ, Manral P, Dowler J et al. Nuclear LC3 associates with slowly diffusing complexes that survey the nucleolus. Traffic. 2016-01-05 [PMID: 26728248] (WB, Human)	WB	Human
Masuda GO, Yashiro M, Kitayama K et al. Clinicopathological Correlations of Autophagy-related Proteins LC3, Beclin 1 and p62 in Gastric Cancer. Anticancer Res. 2016-01-01 [PMID: 26722036] (IHC-P, Human)	IHC-P	Human
Buzgariu W, Al Haddad S, Tomczyk S et al. Multi-functionality and plasticity characterize epithelial cells in Hydra. Tissue Barriers 2015-10-01 [PMID: 26716072]
Yuan R, Geng S, Chen K et al. Low-grade inflammatory polarization of monocytes impairs wound healing J Pathol 2015-12-22 [PMID: 26690561] (ICC/IF, Mouse) Details: This citation used the Alexa Fluor 488 version of this antibody.	ICC/IF	Mouse
Lee E, Lee CG, Yim JH et al. Ramalin-Mediated Apoptosis Is Enhanced by Autophagy Inhibition in Human Breast Cancer Cells. Phytother Res. 2015-12-17 [PMID: 26676298] (WB, Human) Details: LC3B antibody was used for WB analysis of lysates from human breast cancer MCF-7 cells and MDA-MB-231 cells which were treated or not with Ramalin, a chemical compound from the Antarctic lichen Ramalina terebrata which is known to exhibit antioxidant and antiinflammatory activities.	WB	Human
Avagliano L, Doi P, Tosi D et al. Cell death and cell proliferation in human spina bifida. Birth Defects Res. Part A Clin. Mol. Teratol. 2015-12-10 [PMID: 26663582] (IHC-P, Mouse)	IHC-P	Mouse
Stotland A, Gottlieb RA. alpha-MHC MitoTimer mouse: In vivo mitochondrial turnover model reveals remarkable mitochondrial heterogeneity in the heart. J. Mol. Cell. Cardiol. 2015-12-02 [PMID: 26654779] (ICC/IF, Mouse)	ICC/IF	Mouse
Fritzen AM, Madsen AB, Kleinert M et al. Regulation of autophagy in human skeletal muscle - Effects of exercise, exercise training and insulin stimulation. J. Physiol. (Lond.). 2015-11-28 [PMID: 26614120] (WB, Human)	WB	Human
Zhang J, Zhou W, Lin J et al. Autophagic lysosomal reformation depends on mTOR reactivation in H2O2-induced autophagy. Int. J. Biochem. Cell Biol. 2015-11-14 [PMID: 26589722] (ICC/IF, Human)	ICC/IF	Human
Park YS, Park JH, Ko J et al. mTOR inhibition by rapamycin protects against deltamethrin-induced apoptosis in PC12 Cells. Environ. Toxicol. 2015-11-21 [PMID: 26588882] (WB, ICC/IF, Rat)	WB, ICC/IF	Rat
Chandra P, Ghanwat S, Matta SK et al. Mycobacterium tuberculosis Inhibits RAB7 Recruitment to Selectively Modulate Autophagy Flux in Macrophages. Sci Rep. 2015-11-06 [PMID: 26541268] (ICC/IF, Human)	ICC/IF	Human
Majumder P, Chakrabarti O. Mahogunin regulates fusion between amphisomes/MVBs and lysosomes via ubiquitination of TSG101. Cell Death Dis. 2015-11-06 [PMID: 26539917] (WB, Human)	WB	Human
Lin CL, Cheng YS, Li HH et al. Amyloid-beta suppresses AMP-activated protein kinase (AMPK) signaling and contributes to alpha-synuclein-induced cytotoxicity. Exp Neurol 2016-01-01 [PMID: 26515689]
Lin CW, Chen YS, Lin CC et al. Amiodarone as an autophagy promoter reduces liver injury and enhances liver regeneration and survival in mice after partial hepatectomy. Sci Rep. 2015-10-30 [PMID: 26515640] (WB, Mouse)	WB	Mouse
Jiang Q, Li RP, Tang Y et al. Bakkenolide-IIIa Protects Against Cerebral Damage Via Inhibiting NF-kB Activation. CNS Neurosci Ther. 2015-10-28 [PMID: 26511680] (WB, Rat)	WB	Rat
Mahli A, Thasler WE, Patsenker E et al. Identification of cytochrome CYP2E1 as critical mediator of synergistic effects of alcohol and cellular lipid accumulation in hepatocytes in vitro. Oncotarget 2015-12-08 [PMID: 26497211]
Venant H, Rahmaniyan M, Jones EE et al. The Sphingosine Kinase 2 Inhibitor ABC294640 Reduces the Growth of Prostate Cancer Cells and Results in Accumulation of Dihydroceramides In Vitro and In Vivo. Mol Cancer Ther 2015-12-01 [PMID: 26494858]
Lytvynchuk L, Sergienko A, Lavrenchuk G, Petrovski G Antiproliferative, Apoptotic, and Autophagic Activity of Ranibizumab, Bevacizumab, Pegaptanib, and Aflibercept on Fibroblasts: Implication for Choroidal Neovascularization. J Ophthalmol 2015-09-27 [PMID: 26491557]
Jo DS, Bae DJ, Park SJ et al. Pexophagy is induced by increasing peroxisomal reactive oxygen species in 1'10-phenanthroline-treated cells. Biochem Biophys Res Commun 2015-11-13 [PMID: 26453011]
Chandrika BB, Yang C, Ou Y et al. Endoplasmic Reticulum Stress-Induced Autophagy Provides Cytoprotection from Chemical Hypoxia and Oxidant Injury and Ameliorates Renal Ischemia-Reperfusion Injury. PLoS One 2015-01-01 [PMID: 26444017] (ICC/IF)	ICC/IF
Fan XY, Tian C, Wang H et al. Activation of the AMPK-ULK1 pathway plays an important role in autophagy during prion infection. Sci Rep 2015-01-01 [PMID: 26423766]
Delaney JR, Patel C, McCabe KE et al. A strategy to combine pathway-targeted low toxicity drugs in ovarian cancer. Oncotarget 2015-10-13 [PMID: 26418751] (WB)	WB
Wei PF, Jin PP, Barui AK et al. Differential ERK activation during autophagy induced by europium hydroxide nanorods and trehalose: Maximum clearance of huntingtin aggregates through combined treatment. Biomaterials 2015-09-11 [PMID: 26409001] (WB, ICC/IF, Human)	WB, ICC/IF	Human
Sorrell SL, Golder ZJ, Johnstone DB, Karet Frankl FE. Renal peroxiredoxin 6 interacts with anion exchanger 1 and plays a novel role in pH homeostasis. Kidney Int. 2015-09-23 [PMID: 26398495] (IHC-P, Mouse)	IHC-P	Mouse
Granato M, Santarelli R, Filardi M et al. The activation of KSHV lytic cycle blocks autophagy in PEL cells. Autophagy 2015-09-21 [PMID: 26391343] (WB, Human)	WB	Human
Koukourakis MI, Kalamida D, Giatromanolaki A et al. Autophagosome Proteins LC3A, LC3B and LC3C Have Distinct Subcellular Distribution Kinetics and Expression in Cancer Cell Lines. PLoS One 2015-01-01 [PMID: 26378792] (WB, Human)	WB	Human
Du TT, Wang L, Duan CL et al. GBA deficiency promotes SNCA/a-synuclein accumulation through autophagic inhibition by inactivated PPP2A. Autophagy 2015-09-17 [PMID: 26378614] (WB, Mouse)	WB	Mouse
Keatinge M, Bui H, Menke A et al. Glucocerebrosidase 1 deficient Danio rerio mirror key pathological aspects of human Gaucher disease and provide evidence of early microglial activation preceding alpha-synuclein-independent neuronal cell death. Hum. Mol. Genet. 2015-09-16 [PMID: 26376862] (WB, Zebrafish)	WB	Zebrafish
Pellegrini C, Columbaro M, Capanni C et al. All-trans retinoic acid and rapamycin normalize Hutchinson Gilford progeria fibroblast phenotype. Oncotarget 2015-10-06 [PMID: 26359359] (WB)	WB
You Dalsan, Kim Yunlim, Jang Myoung Jin et al. KML001 Induces Apoptosis and Autophagic Cell Death in Prostate Cancer Cells via Oxidative Stress Pathway. PloS One 2015-01-01 [PMID: 26352139] (WB, Mouse)	WB	Mouse
Granato M, Gilardini Montani MS, Filardi M et al. Capsaicin triggers immunogenic PEL cell death, stimulates DCs and reverts PEL-induced immune suppression. Oncotarget 2015-10-06 [PMID: 26338963]
Sibony Michal, Abdullah Majd, Greenfield Laura et al. Microbial Disruption of Autophagy Alters Expression of the RISC Component AGO2, a Critical Regulator of the miRNA Silencing Pathway. Inflammatory Bowel Diseases 2015-01-01 [PMID: 26332312] (WB, Mouse)	WB	Mouse
Chen CM, Syu JP, Way TD et al. BC3EE2,9B, a synthetic carbazole derivative, upregulates autophagy and synergistically sensitizes human GBM8901 glioblastoma cells to temozolomide. Int. J. Mol. Med. 2015-09-01 [PMID: 26329365] (ICC/IF, WB, Human) Details: LC3 antiboldy was used for WB and ICC-IF assays in experiments involving BC3EE2,9B, a synthetic carbazole derivative, effects on glioblastoma cell lines GBM8901 and GBM8401, and human normal skin cell line Detroit 551 cells.	ICC/IF, WB	Human
Tsukahara T, Haniu H. The PTB-Associated Splicing Factor/Peroxisome Proliferator-Activated Receptor Gamma Axis Regulates Autophagosome Formation in Human Pancreatic Cancer Cells BioResearch Open Access 2015-07-02 [PMID: 26309807] (WB, Human) Details: LC3 antibody was used for WB on lysates of human pancreatic cancer cells lines MIA-PaCa-2 and Panc-1 that were subjected to treatoments ith control siRNA or PSF siRNA (Figure 3C). WB was also performed on Panc-1 cells transfected with a pcDNA3.1 empty vector or vector containing PSF (Figure 3D).	WB	Human
Pal I, Parida S, Prashanth Kumar BN et al. Blockade of autophagy enhances proapoptotic potential of BI-69A11, a novel Akt inhibitor, in colon carcinoma. Eur. J. Pharmacol. 2015-08-22 [PMID: 26306675] (WB, ICC/IF, Human)	WB, ICC/IF	Human
Yadav RK, Lee GH, Lee HY et al. TMBIM6 (transmembrane BAX inhibitor motif containing 6) Enhances Autophagy and Reduces Renal Dysfunction in a Cyclosporine A-induced nephrotoxicity model. Autophagy. 2015-08-25 [PMID: 26305401] (WB, Human)	WB	Human
Moreau K, Ghislat G, Hochfeld W et al. Transcriptional regulation of Annexin A2 promotes starvation-induced autophagy. Nat Commun. 2015-08-20 [PMID: 26289944] (WB, Human, Mouse)	WB	Human, Mouse
El-Mashed S, O'Donovan TR, Kay EW et al. LC3B globular structures correlate with survival in esophageal adenocarcinoma. BMC Cancer. 2015-08-12 [PMID: 26265176] (IHC-P, Human)	IHC-P	Human
Li T, Sun KJ, Wang HD et al. Tert-butylhydroquinone Ameliorates Early Brain Injury After Experimental Subarachnoid Hemorrhage in Mice by Enhancing Nrf2-Independent Autophagy. Neurochem. Res. 2015-09-01 [PMID: 26260377] (WB, Mouse)	WB	Mouse
Lee YH, Chen HY, Su LJ, Chueh PJ. Sirtuin 1 (SIRT1) Deacetylase Activity and NAD(+)/NADH Ratio Are Imperative for Capsaicin-Mediated Programmed Cell Death. J. Agric. Food Chem. 2015-08-26 [PMID: 26255724] (WB, Human) Details: ATG7 antibody was use for WB on lysates of MRC-5 normal human foetal lung fibroblast cells and adenocarcinomic human alveolar basal epithelial cell line A549 that were treated or not with Capsaicin or ethanol.	WB	Human
Yakoub AM, Shukla D. Basal Autophagy Is Required for Herpes simplex Virus-2 Infection. Sci Rep. 2015-08-07 [PMID: 26248741] (WB, Human)	WB	Human
Triplett JC, Tramutola A, Swomley A et al. Age-related changes in the proteostasis network in the brain of the naked mole-rat: Implications promoting healthy longevity. Biochim. Biophys. Acta. 2015-10-01 [PMID: 26248058] (WB, Rat) Details: LC3B/MAP1LC3B antibody was used for WB detection of LC3-I and LC3-II in brain tissues from naked mole-rats of different different age groups (Fig. 8 ).	WB	Rat
Xiong X, Wu M, Zhang H et al. Atg5 siRNA inhibits autophagy and enhances norcantharidin-induced apoptosis in hepatocellular carcinoma. Int. J. Oncol. 2015-07-24 [PMID: 26240015] (WB, Human)	WB	Human
Streeter A, Menzies FM, Rubinsztein DC. LC3-II Tagging and Western Blotting for Monitoring Autophagic Activity in Mammalian Cells. Methods Mol. Biol. 2015-08-03 [PMID: 26235065] (WB, Human)	WB	Human
Ngoh EN, Brugger HK, Monajemi M et al. The Crohn's disease-associated polymorphism in ATG16L1 (rs2241880) reduces SHIP gene expression and activity in human subjects. Genes Immun. 2015-07-30 [PMID: 26226011] (WB, Human, Mouse)	WB	Human, Mouse
Matta SK, Kumar D et al. AKT mediated glycolytic shift regulates autophagy in classically activated macrophages Int. J. Biochem. Cell Biol. 2015-07-26 [PMID: 26222186] (WB, Mouse)	WB	Mouse
Chesser AS, Ganeshan V, Yang J, Johnson GV et al. Epigallocatechin-3-gallate enhances clearance of phosphorylated tau in primary neurons Nutr Neurosci. 2015-07-24 [PMID: 26207957]
Wu HM, Jiang ZF, Ding PS et al. Hypoxia-induced autophagy mediates cisplatin resistance in lung cancer cells Sci Rep. 2015-07-23 [PMID: 26201611] (WB, Human)	WB	Human
Granato M, Chiozzi B, Filardi MR et al. Tyrosine kinase inhibitor tyrphostin AG490 triggers both apoptosis and autophagy by reducing HSF1 and Mcl-1 in PEL cells Cancer Lett. 2015-07-01 [PMID: 26184999] (WB, Human)	WB	Human
Herpin A, Englberger E, Zehner M et al. Defective autophagy through epg5 mutation results in failure to reduce germ plasm and mitochondria. FASEB J 2015-10-01 [PMID: 26183773]
Wang IK, Sun KT, Tsai TH et al. MiR-20a-5p mediates hypoxia-induced autophagy by targeting ATG16L1 in ischemic kidney injury Life Sci. 2015-07-10 [PMID: 26165754] (WB, ICC/IF, Human)	WB, ICC/IF	Human
Tong Y, Sun Y et al. Phospholipid transfer protein (PLTP) deficiency accelerates memory dysfunction through altering amyloid precursor protein (APP) processing in a mouse model of Alzheimer's disease. Hum Mol Genet 2015-01-10 [PMID: 26160914] (IF/IHC, Mouse)	IF/IHC	Mouse
Shin JH, Bae DJ, Kim ES et al. Autophagy Regulates Formation of Primary Cilia in Mefloquine-Treated Cells Biomol Ther (Seoul). 2015-07-01 [PMID: 26157548] (WB, Human)	WB	Human
Schiattarella GG, Cerulo G, De Pasquale V et al. The Murine Model of Mucopolysaccharidosis IIIB Develops Cardiopathies over Time Leading to Heart Failure PLoS ONE. 2015-07-07 [PMID: 26147524] (WB, Mouse) Details: LC3 antibody was used for WB analysis of heart/cardiac tissue lysates from WT and alpha-N-acetylglucosaminidase(NAGLU) -/- mice (Fig 6).	WB	Mouse
Agarwal S, Tiwari SK, Seth B et al. Activation of autophagic flux against xenoestrogen Bisphenol-A induced hippocampal neurodegeneration via AMPK/mTOR pathways J. Biol. Chem. 2015-07-02 [PMID: 26139607] (WB, Rat)	WB	Rat
Hrabeta J, Groh T, Khalil MA et al. Vacuolar-ATPase-mediated intracellular sequestration of ellipticine contributes to drug resistance in neuroblastoma cells Int. J. Oncol. 2015-06-29 [PMID: 26134421] (WB, Human) Details: LC3 antibody was used for WB assay in experiments involving ellipticine-resistant UKF-NB-4ELLI cell line and its parental ellipticine-sensitive human neuroblastoma UKF-NB-4 cell line.	WB	Human
Lee HO, Mustafa A, Hudes GR, Kruger WD. Hydroxychloroquine Destabilizes Phospho-S6 in Human Renal Carcinoma Cells. PLoS One. 2015-07-02 [PMID: 26134285] (WB, Human)	WB	Human
Campbell GR, Rawat P, Bruckman RS, Spector SA. Human Immunodeficiency Virus Type 1 Nef Inhibits Autophagy through Transcription Factor EB Sequestration PLoS Pathog. 2015-06-01 [PMID: 26115100] (WB, Human)	WB	Human
Godar RJ, Ma X, Liu H et al. Repetitive stimulation of autophagy-lysosome machinery by intermittent fasting preconditions the myocardium to ischemia-reperfusion injury. Autophagy 2015-01-01 [PMID: 26103523] (WB)	WB
Liu KE, Frazier WA. Phosphorylation of the BNIP3 C-Terminus Inhibits Mitochondrial Damage and Cell Death without Blocking Autophagy PLoS ONE. 2015-06-24 [PMID: 26102349] (WB, Human)	WB	Human
Zhang L, Ding K, Wang H et al. Traumatic Brain Injury-Induced Neuronal Apoptosis is Reduced Through Modulation of PI3K and Autophagy Pathways in Mouse by FTY720 Cell. Mol. Neurobiol. 2015-06-23 [PMID: 26099903] (WB, Mouse)	WB	Mouse
He B, Zhang N, Zhao R. Dexamethasone Downregulates SLC7A5 Expression and Promotes Cell Cycle Arrest, Autophagy and Apoptosis in BeWo Cells. J Cell Physiol 2016-01-01 [PMID: 26094588]
Shelby Shameka J, Angadi Pavan S, Zheng Qiong-Duon et al. Hypoxia inducible factor 1a contributes to regulation of autophagy in retinal detachment. Experimental Eye Research 2015-01-01 [PMID: 26093278] (IF/IHC, Rat)	IF/IHC	Rat
Cheng D, Weckerle A, Yu Y et al. Biogenesis and cytotoxicity of APOL1 renal-risk variant proteins in hepatocytes and hepatoma cells J. Lipid Res. 2015-06-18 [PMID: 26089538]
Park S, Choi SG, Yoo SM et al. Pyruvate stimulates mitophagy via PINK1 stabilization Cell. Signal. 2015-06-09 [PMID: 26071202]
Karanasios E, Ktistakis NT. Studying Autophagy: List of Useful Antibodies Produced via a Community Effort. Autophagy at the Cell, Tissue and Organismal Level. 2016-04-24
Guo ML, Liao K, Periyasamy P et al. Cocaine-mediated microglial activation involves the ER stress-autophagy axis. Autophagy 2015-01-01 [PMID: 26043790] (WB)	WB
Zhang R, Li Y, Wang Z et al. Interference with HMGB1 increases the sensitivity to chemotherapy drugs by inhibiting HMGB1-mediated cell autophagy and inducing cell apoptosis. Tumour Biol 2015-06-04 [PMID: 26040768]
Teng AC, Miyake T, Yokoe S et al. Metformin increases degradation of phospholamban via autophagy in cardiomyocytes Proc Natl Acad Sci U S A. 2015-06-08 [PMID: 26040000] (WB, Human)	WB	Human
Dangi A, Huang C, Tandon A et al. Endotoxin-Stimulated Rat Hepatic Stellate Cells Induce Autophagy in Hepatocytes as a Survival Mechanism. J Cell Physiol 2015-05-29 [PMID: 26031389] (Rat)		Rat
Li L, Wang X, Wang L et al. Mammalian target of rapamycin overexpression antagonizes chronic hypoxia-triggered pulmonary arterial hypertension via the autophagic pathway. Int J Mol Med 2015-07-01 [PMID: 26017061]
Sun T, Li X, Zhang P et al. Acetylation of Beclin 1 inhibits autophagosome maturation and promotes tumour growth. Nat Commun. 2015-05-26 [PMID: 26008601] (WB, Human)	WB	Human
Namkoong S, Lee KI, Lee JI et al. The integral membrane protein ITM2A, a transcriptional target of PKA-CREB, regulates autophagic flux via interaction with the vacuolar ATPase. Autophagy. 2015-05-04 [PMID: 25951193] (WB, Human)	WB	Human
Mintern JD, Macri C, Chin WJ et al. Differential use of autophagy by primary dendritic cells specialised in cross-presentation. Autophagy. 2015-05-07 [PMID: 25950899] (WB, Mouse, Human)	WB	Mouse, Human
Jung R, Choi JH, Lee HJ et al. Effect of Immortalization-Upregulated Protein-2 (IMUP-2) on Cell Death of Trophoblast. Balsaenggwa Saengsig 2013-06-01 [PMID: 25949126]
Kim Y, Kang YS, Lee NY et al. Uvrag targeting by Mir125a and Mir351 modulates autophagy associated with Ewsr1 deficiency. Autophagy. 2015-05-04 [PMID: 25946189] (WB, Mouse)	WB	Mouse
Gavilan E, Giraldez S, Sanchez-Aguayo I et al. Breast cancer cell line MCF7 escapes from G1/S arrest induced by proteasome inhibition through a GSK-3B dependent mechanism. Sci Rep. 2015-05-05 [PMID: 25941117] (ICC/IF, WB, Human)	ICC/IF, WB	Human
Carson CC, Moschos SJ, Edmiston SN et al. IL2 Inducible T-cell Kinase, a Novel Therapeutic Target in Melanoma. Clin. Cancer Res. 2015-05-01 [PMID: 25934889] (WB, Human)	WB	Human
Shibuya Y, Niu Z, Bryleva EY et al. Acyl-coenzyme A:cholesterol acyltransferase 1 blockage enhances autophagy in the neurons of triple transgenic Alzheimer's disease mouse and reduces human P301L-tau content at the presymptomatic stage Neurobiol. Aging 2015-01-01 [PMID: 25930235] (WB, Mouse)	WB	Mouse
Yao J, Zheng K, Li C et al. Interference of Notch1 inhibits the growth of glioma cancer cells by inducing cell autophagy and down-regulation of Notch1-Hes-1 signaling pathway. Med. Oncol. 2015-05-01 [PMID: 25920606] (WB, Human)	WB	Human
Ariadna Laguna, Nicoletta Schintu, Andre Nobre et al. Dopaminergic control of autophagic-lysosomal function implicates Lmx1b in Parkinsons disease. Nature Neuroscience 2015-04-27 [PMID: 25915474] (WB, Mouse)	WB	Mouse
Wang S, Livingston MJ, Su Y, Dong, Z. Reciprocal regulation of cilia and autophagy via the MTOR and proteasome pathways Autophagy 2015-04-23 [PMID: 25906314] (WB, Human)	WB	Human
Cabrera S, Maciel M, Herrera I et al. Essential role for the ATG4B protease and autophagy in bleomycin-induced pulmonary fibrosis Autophagy 2015-04-23 [PMID: 25906080] (ICC/IF, Mouse)	ICC/IF	Mouse
Levi B Watkin, Birthe Jessen, Wojciech Wiszniewski et al. COPA mutations impair ER-Golgi transport and cause hereditary autoimmune-mediated lung disease and arthritis. Nature Genetics 2015-04-20 [PMID: 25894502] (IF/IHC, Human)	IF/IHC	Human
Yakoub AM, Shukla D. Herpes Simplex Virus-1 Fine-Tunes Host's Autophagic Response to Infection: A Comprehensive Analysis in Productive Infection Models PLoS ONE 2015-04-21 [PMID: 25894397] (WB, Human)	WB	Human
Yakoub AM, Shukla D. Autophagy Stimulation Abrogates Herpes simplex Virus-1 Infection Sci Rep 2015-04-10 [PMID: 25856282] (WB, Human, Mouse)	WB	Human, Mouse
Kett LR, Stiller B, Bernath MM et al. alpha-Synuclein-Independent Histopathological and Motor Deficits in Mice Lacking the Endolysosomal Parkinsonism Protein Atp13a2 J. Neurosci. 2015-04-08 [PMID: 25855184] (WB, Mouse)	WB	Mouse
Jimenez-Sanchez M, Lam W, Hannus M et al. siRNA screen identifies QPCT as a druggable target for Huntington's disease. Nat Chem Biol 2015-05-01 [PMID: 25848931]
Tam BT, Pei XM, Yu AP et al. Autophagic adaptation is associated with exercise-induced fibre-type shifting in skeletal muscle Acta Physiol (Oxf) 2015-04-06 [PMID: 25847142] (IHC-Fr, WB, Rat)	IHC-Fr, WB	Rat
Pajuelo-Reguera D, Alan L et al. Dichloroacetate stimulates changes in the mitochondrial network morphology via partial mitophagy in human SH-SY5Y neuroblastoma cells. Int J Oncol 2015-08-04 [PMID: 25846762] (WB, Human)	WB	Human
Chandler HL, Gervais KJ, Lutz EA et al. Cyclosporine A prevents ex vivo PCO formation through induction of autophagy-mediated cell death Exp. Eye Res. 2015-03-31 [PMID: 25839646] (IF/IHC, WB, Canine)	IF/IHC, WB	Canine
Yue M, Hinkle KM, Davies P et al. Progressive dopaminergic alterations and mitochondrial abnormalities in LRRK2 G2019S knock-in mice Neurobiol. Dis. 2015-03-31 [PMID: 25836420] (WB, Mouse)	WB	Mouse
Gonnella R, Granato M, Farina A et al. PKC theta and p38 MAPK activate the EBV lytic cycle through autophagy induction. Biochim. Biophys. Acta. 2015-03-27 [PMID: 25827954] (WB, Human)	WB	Human
Liu S, Li X. Autophagy inhibition enhances sensitivity of endometrial carcinoma cells to paclitaxel Int. J. Oncol. 2015-06-01 [PMID: 25825088] (WB, Human)	WB	Human
Van Nostrand JL, Brisac A, Mello SS et al. The p53 Target Gene Siva Enables Non-Small Cell Lung Cancer Development Cancer Discov 2015-03-26 [PMID: 25813352] (WB, Mouse)	WB	Mouse
Roux C, Aligny C, Lesueur C et al. NMDA receptor blockade in the developing cortex induces autophagy-mediated death of immature cortical GABAergic interneurons: An ex vivo and in vivo study in Gad67-GFP mice. Exp. Neurol. 2015-03-17 [PMID: 25795167] (WB, Mouse)	WB	Mouse
Labouba I, Poisson A, Lafontaine J et al. The RelB alternative NF-kappaB subunit promotes autophagy in 22Rv1 prostate cancer cells in vitro and affects mouse xenograft tumor growth in vivo. Cancer Cell Int 2014-01-01 [PMID: 25788857] (WB, Mouse)	WB	Mouse
Magne J, Gustafsson P et al. ATG16L1 Expression in Carotid Atherosclerotic Plaques Is Associated With Plaque Vulnerability. Arterioscler Thromb Vasc Biol 2015-01-05 [PMID: 25767270] (WB, Human)	WB	Human
Suarez G, Romero-Gallo J, Piazuelo MB et al. Modification of Helicobacter pylori Peptidoglycan Enhances NOD1 Activation and Promotes Cancer of the Stomach Cancer Res. 2015-03-02 [PMID: 25732381] (WB, Human) Details: LC3B/MAP1LC3B antibody used for WB on lysates of gastric adenocarcinoma cell line namely AGS cells co-cultured or not with Helicobacter pylori ( WT strain 7.13 or its pgdA- mutant ). The WB assay involved 12% SDS-PAGE gel, protein transfer to PVDF membrane, blocking of membranes with 1% BSA, incubation with primary antibody at 1:500 dilution for 1 hour and detection with anti-rabbit HRP-conjugated secondary - ECL method (Figure 2B)	WB	Human
She T, Qu L, Wang L et al. Sarsaparilla (Smilax Glabra Rhizome) Extract Inhibits Cancer Cell Growth by S Phase Arrest, Apoptosis and Autophagy via Redox-dependent ERK1/2 Pathway Cancer Prev Res (Phila) 2015-03-02 [PMID: 25732255] (WB, Human) Details: LC3B/MAP1LC3B antibody used for WB on lysates of human stomach/gastric adenocarcinoma cell line AGS and human colorectal adenocarcinoma cell line HT-29 treated or not with supernatant of the water-soluble extract of Sarsaparilla/SW (Smilax Glabra Rhizome). WB also performed on lysates of these cells treated with SW and/or GSH, U0126 (selective inhibitor of both MEK1 and MEK2) or PD98059 (selective inhibitor of MAPK/ERK kinase).	WB	Human
Medina DL, Di Paola S, Peluso I et al. Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB Nat. Cell Biol. 2015-02-27 [PMID: 25720963] (WB, ICC/IF, Human)	WB, ICC/IF	Human
Hsuan SW, Chyau CC, Hung HY et al. The induction of apoptosis and autophagy by Wasabia japonica extract in colon cancer Eur J Nutr 2015-02-27 [PMID: 25720497] (WB, Human)	WB	Human
Pedro JM, Wei Y, Sica V et al. BAX and BAK1 are dispensable for ABT-737-induced dissociation of the BCL2-BECN1 complex and autophagy. Autophagy 2015-01-01 [PMID: 25715028] (IP, Mouse)	IP	Mouse
Ulbricht A, Gehlert S, Leciejewski B et al. Induction and adaptation of chaperone-assisted selective autophagy CASA in response to resistance exercise in human skeletal muscle Autophagy. 2015-02-25 [PMID: 25714469] (IF/IHC, Human)	IF/IHC	Human
Sanjurjo L, Amezaga N, Aran G et al. The human CD5L/AIM-CD36 axis: A novel autophagy inducer in macrophages that modulates inflammatory responses Autophagy. 2015-02-25 [PMID: 25713983] (WB, ICC/IF, Human)	WB, ICC/IF	Human
Chen JH, Zhang P, Chen WD et al. ATM-mediated PTEN phosphorylation promotes PTEN nuclear translocation and autophagy in response to DNA-damaging agents in cancer cells Autophagy. 2015-02-20 [PMID: 25701194] (ICC/IF, WB, Human)	ICC/IF, WB	Human
Jabir MS, Hopkins L, Ritchie ND et al. Mitochondrial damage contributes to Pseudomonas aeruginosa activation of the inflammasome and is downregulated by autophagy. Autophagy 2015-01-01 [PMID: 25700738] (WB)	WB
Kim ES, Shin JH, Park SJ et al. Inhibition of autophagy suppresses sertraline-mediated primary ciliogenesis in retinal pigment epithelium cells PLoS ONE. 2015-02-12 [PMID: 25671433] (WB, Human)	WB	Human
Kommaddi RP, Jean-Charles PY, Shenoy SK. Phosphorylation of the deubiquitinase USP20 by Protein Kinase A regulates post-endocytic trafficking of beta 2 adrenergic receptors to autophagosomes during physiological stress J. Biol. Chem. 2015-02-09 [PMID: 25666616] (WB, Human)	WB	Human
Ito S, Tanaka Y, Oshino R et al. GADD34 inhibits activation-induced apoptosis of macrophages through enhancement of autophagy Sci Rep. 2015-02-09 [PMID: 25659802] (WB, Mouse)	WB	Mouse
Lin HH. In Vitro and in Vivo Atheroprotective Effects of Gossypetin against Endothelial Cell Injury by Induction of Autophagy. Chem Res Toxicol. 2015-01-29 [PMID: 25622137]
Yuan N, Song L, Lin W et al. Autophagy collaborates with ubiquitination to downregulate oncoprotein E2A/Pbx1 in B-cell acute lymphoblastic leukemia. Blood Cancer J. 2015-01-24 [PMID: 25615280] (WB, Mouse)	WB	Mouse
Yang M, Liu L, Xie M et al. Poly-ADP-ribosylation of HMGB1 regulates TNFSF10/TRAIL resistance through autophagy Autophagy. 2015-01-21 [PMID: 25607248]
Yan Y, Jiang W, Liu L et al. Dopamine Controls Systemic Inflammation through Inhibition of NLRP3 Inflammasome Cell. 2015-01-15 [PMID: 25594175] (WB, Mouse)	WB	Mouse
Baker B, Geng S, Chen K et al. Alteration of lysosome fusion and low-grade inflammation mediated by super-low dose endotoxin . J Biol Chem 2015-01-13 [PMID: 25586187] (IF/IHC, Mouse) Details: Using the Alexa Fluor (R) 488 conjugated version of NB100-2220, catalog number NB100-2220AF488.	IF/IHC	Mouse
Xu Y, Tian C, Sun J et al. FBXW7-Induced MTOR Degradation Forces Autophagy to Counteract Persistent Prion Infection Mol. Neurobiol. 2015-01-13 [PMID: 25579381] (WB, Mouse) Details: LC3B/MAP1LC3B antibody used for WB on SMB-PS and SMB-S15 cell lines (murine cell line, persistent prion infection/scrapie-infected) - data is shown in Fig 1a and higher levels of LC3II were observed in SMB-S15 cells compared to SMB-P.	WB	Mouse
Maycotte P, Jones KL, Goodall ML et al. Autophagy Supports Breast Cancer Stem Cell Maintenance by Regulating IL6 Secretion. Mol Cancer Res 2015-04-01 [PMID: 25573951]
Liu S, Sarkar C, Dinizo M et al. Disrupted autophagy after spinal cord injury is associated with ER stress and neuronal cell death. Cell Death Dis 2015-01-01 [PMID: 25569099] (Rat)		Rat
Bueno M, Lai Y, Romero Y et al. PINK1 deficiency impairs mitochondrial homeostasis and promotes lung fibrosis. J. Clin. Invest. 2014-12-22 [PMID: 25562319] (IF/IHC, Mouse)	IF/IHC	Mouse
Sykora P, Misiak M, Wang Y et al. DNA polymerase b deficiency leads to neurodegeneration and exacerbates Alzheimer disease phenotypes. Nucleic Acids Res 2014-12-30 [PMID: 25552414] (WB, Mouse) Details: Using the DyLight 550 conjugated version of NB100-304, catalog number NB100-304R.	WB	Mouse
Sampaolo S, Esposito T, Gianfrancesco F et al. A novel GBE1 mutation and features of polyglucosan bodies autophagy in adult polyglucosan body disease. Neuromuscular Disorders 2014-11-18 [PMID: 25544507]
Campbell GR, Bruckman RS, Chu Y, Spector SA. Autophagy Induction by Histone Deacetylase Inhibitors Inhibits HIV Type 1. J. Biol. Chem. 2014-12-24 [PMID: 25540204] (WB, Human)	WB	Human
Suarez Christopher D, Deng Xuehong, Hu Chang-Deng. Targeting CREB inhibits radiation-induced neuroendocrine differentiation and increases radiation-induced cell death in prostate cancer cells. Am J Cancer Res. 2014-11-19 [PMID: 25520873] (WB)	WB
Krishnaswamy S, Lin Y, Rajamohamedsait WJ et al. Antibody-derived in vivo imaging of tau pathology. J. Neurosci. 2014-12-10 [PMID: 25505335] (IF/IHC, Mouse)	IF/IHC	Mouse
Cossette SM, Gastonguay AJ, Bao X et al. Sucrose non-fermenting related kinase enzyme is essential for cardiac metabolism. Biol Open. 2014-12-12 [PMID: 25505152] (WB, Mouse)	WB	Mouse
Johnson CE, Hunt DK, Wiltshire M et al. Endoplasmic reticulum stress and cell death in mTORC1-overactive cells is induced by nelfinavir and enhanced by chloroquine. Mol Oncol. 2014-11-22 [PMID: 25498902] (WB, Human)	WB	Human
Varga M, Fodor E, Vellai T. Autophagy in zebrafish. Methods. 2014-12-09 [PMID: 25498006] (WB, Zebrafish)	WB	Zebrafish
Raval KK, Tao R, White BE et al. Pompe disease results in a Golgi-based glycosylation deficit in human induced pluripotent stem cell-derived cardiomyocytes. J. Biol. Chem. 2014-12-08 [PMID: 25488666] (WB, Human) Details: LC3B/MAP1LC3B antibody used for WB and ICC-IF in experiments involving human Induced Pluripotent Stem Cell-derived Cardiomyocytes.	WB	Human
Sun KT, Chen MY, Tu MG et al. MicroRNA-20a regulates autophagy related protein-ATG16L1 in hypoxia-induced osteoclast differentiation. Bone. 2014-12-05 [PMID: 25485521] (ICC/IF, WB, Mouse) Details: p62/SQSTM1 antibody used for WB on RAW264.7 cells subjected to RANKL and M-CSF mediated osteoclast differentiation as well as hypoxic stress (Fig. 1E )	ICC/IF, WB	Mouse
Mitter SK, Song C, Qi X et al. Dysregulated autophagy in the RPE is associated with increased susceptibility to oxidative stress and AMD. Autophagy 2014-01-01 [PMID: 25484094] (WB)	WB
Sarkar C, Zhao Z, Aungst S et al. Impaired autophagy flux is associated with neuronal cell death after traumatic brain injury. Autophagy 2014-01-01 [PMID: 25484084] (WB)	WB
Lin J, Huang Z, Wu H et al. Inhibition of autophagy enhances the anticancer activity of silver nanoparticles. Autophagy 2014-01-01 [PMID: 25484080] (WB)	WB
Lu Y, Dong S, Hao B et al. Vacuolin-1 potently and reversibly inhibits autophagosome-lysosome fusion by activating RAB5A. Autophagy 2014-10-30 [PMID: 25483964] (WB)	WB
Park S, Choi SG, Yoo SM et al. Choline dehydrogenase interacts with SQSTM1/p62 to recruit LC3 and stimulate mitophagy. Autophagy 2014-10-30 [PMID: 25483962] (WB)	WB
Weng Z, Luo Y, Yang X et al. Regorafenib impairs mitochondrial functions, activates AMP-activated protein kinase, induces autophagy, and causes rat hepatocyte necrosis. Toxicology. 2014-11-06 [PMID: 25445804]
Clark O, Park I, Di Florio A et al. Oxovanadium-based inhibitors can drive redox-sensitive cytotoxicity in neuroblastoma cells and synergise strongly with buthionine sulfoximine. Cancer Lett. 2014-11-20 [PMID: 25444896] (WB, Human)	WB	Human
Ohia-Nwoko O, Montazari S, Lau YS, Eriksen JL. Long-term treadmill exercise attenuates tau pathology in P301S tau transgenic mice. Mol Neurodegener. 2014-12-16 [PMID: 25432085] (WB, Mouse) Details: LC3B/MAP1LC3B antibody used for WB at 1:500 dilution on lysates of spinal cord, cortex, and hippocampus from sedentary and exercised non-transgenic mice or P301S tau transgenic mice (expresses human tau /1N4R with a P301S mutation). Figure 7B shows the LC3 levels in spinal cord and cortex/hippocampus of various groups - P301S or non-transgenic mice in the sfrom exercised (Tg-EX) and sedentary (Tg-SED) P301S mice along with their non-transgenic exercised (NTg-EX) and sedentary (NTg-SED) counterparts.	WB	Mouse
Schloesser A, Campbell G, Gluer Cc et al. Restriction on an energy dense diet improves markers of metabolic health and cellular ageing in mice through decreasing hepatic mTOR activity. Rejuvenation Res. 2014-11-18 [PMID: 25405871]
Kao C, Chao A, Tsai Cl et al. Bortezomib enhances cancer cell death by blocking the autophagic flux through stimulating ERK phosphorylation Cell Death Dis et al. 2014-11-07 [PMID: 25375375] (WB, Human) Details: LC3B/MAP1LC3B antibody used for WB in experiments involving human ovarian cancer cell lines TOV112D, TOV21G, OV90, SKOV3, MDAH2774, ES2, BR and BG1 cells.	WB	Human
Watanabe S, Hayakawa T, Wakasugi K, Yamanaka K. Cystatin C protects neuronal cells against mutant copper-zinc superoxide dismutase-mediated toxicity Cell Death Dis et al. 2014-10-31 [PMID: 25356866] (WB, Mouse) Details: LC3 antibody used for WB on Cystatin C treated n2a cells (neuroblastoma cell neuro2a) which were transfected with SOD1WT or SOD1G85R (Figure 3b). WB also performed on n2a cells treated with CysC, Compound C or AICA-riboside (Figure 4d).	WB	Mouse
Mccabe Ke, Bacos K, Lu D et al. Triggering necroptosis in cisplatin and IAP antagonist-resistant ovarian carcinoma Cell Death Dis et al. 2014-10-31 [PMID: 25356865] (WB, Human)	WB	Human
Yang K C, Ma X et al. Tumor necrosis factor receptor-associated factor 2 mediates mitochondrial autophagy. Circ Heart Fail 2015-01-01 [PMID: 25339503] (WB, Mouse)	WB	Mouse
Benhamron S, Pattanayak Sp, Berger M, Tirosh B. mTOR activation promotes plasma cell differentiation and bypasses XBP-1 for immunoglobulin secretion. Mol Cell Biol 2014-10-20 [PMID: 25332234] (WB, Mouse) Details: Using the HRP conjugated version of NB100-2220, catalog number NB100-2220H.	WB	Mouse
Gao L, Qi Hb, Kc K et al. Excessive autophagy induces the failure of trophoblast invasion and vasculature: possible relevance to the pathogenesis of preeclampsia. J. Hypertens. 2014-10-15 [PMID: 25318653] (ICC/IF, IHC-P, WB, Human)	ICC/IF, IHC-P, WB	Human
Liao Cl, Chen Cm, Chang Yz et al. Pine (Pinus morrisonicola Hayata) needle Extracts Sensitize GBM8901 Human Glioblastoma Cells to Temozolomide by Downregulating Autophagy and O(6)-Methylguanine-DnA Methyltransferase Expression. J. Agric. Food Chem. 2014-10-29 [PMID: 25293350]
Lan Yy, Londono D, Bouley R et al. Dnase2a Deficiency Uncovers Lysosomal Clearance of Damaged nuclear DnA via Autophagy. Cell Rep. 2014-10-09 [PMID: 25284779] (ICC/IF, Mouse)	ICC/IF	Mouse
Yang DS, Stavrides P, Saito M et al. Defective macroautophagic turnover of brain lipids in the TgCRND8 Alzheimer mouse model: prevention by correcting lysosomal proteolytic deficits. Brain. 2014-09-29 [PMID: 25270989] (WB, ICC/IF, IHC-Fr, Mouse)	WB, ICC/IF, IHC-Fr	Mouse
Shanware NP, Bray K, Eng CH et al. Glutamine deprivation stimulates mTOR-JNK-dependent chemokine secretion. Nat Commun. 2014-09-26 [PMID: 25254627]
Moreau K, Fleming A, Imarisio S et al. PICALM modulates autophagy activity and tau accumulation. Nat Commun. 2014-09-22 [PMID: 25241929]
Mazon Moya MJ, Colucci-Guyon E, Mostowy S. Use of Shigella flexneri to Study Autophagy-Cytoskeleton Interactions. J Vis Exp. 2014-09-17 [PMID: 25226510]
Aggresome-Autophagy Involvement in a Sarcopenic Patient with Rigid Spine Syndrome and a p. C150R Mutation in FHL1 Gene. Sabatelli P, Castagnaro S, Tagliavini F Front Aging Neurosci [PMID: 25191266] (IHC-Fr, Human)	IHC-Fr	Human
Granato M, Santarelli R, Farina A et al. EBV blocks the autophagic flux and appropriates the autophagic machinery to enhance viral replication. J Virol. 2014-08-20 [PMID: 25142602] (WB, Primate)	WB	Primate
Morgan MJ, Gamez G, Menke C et al. Regulation of autophagy and chloroquine sensitivity by oncogenic RAS in vitro is context-dependent. Autophagy 2014-10-01 [PMID: 25136801] (WB)	WB
Dunlop EA, Seifan S, Claessens T et al. FLCN, a novel autophagy component, interacts with GABARAP and is regulated by ULK1 phosphorylation. Autophagy 2014-10-01 [PMID: 25126726] (WB)	WB
Hao CL, Li Y, Yang HX et al. High level of microtubule-associated protein light chain 3 predicts poor prognosis in resectable esophageal squamous cell carcinoma. Int J Clin Exp Pathol. 2014-08-14 [PMID: 25120801] (IHC-P, Human) Details: Rabbit anti-LC3 antibody used for IHC on TMA sections that were rehydrated via a graded alcohol series. LC3 antibody used at a dilution of 1:400 for 12 hours at 4 degrees C in a moist chamber (figure 1).	IHC-P	Human
Jiang P, Mukthavaram R, Chao Y et al. In vitro and in vivo anticancer effects of mevalonate pathway modulation on human cancer cells. Br. J Cancer. 2014-08-05 [PMID: 25093497] (WB, Human)	WB	Human
Minoia M, Boncoraglio A, Vinet J et al. BAG3 induces the sequestration of proteasomal clients into cytoplasmic puncta: implications for a proteasome-to-autophagy switch. Autophagy 2014-09-01 [PMID: 25046115] (WB)	WB
Ligeon LA, Moreau K, Barois N et al. Role of VAMP3 and VAMP7 in the commitment of Yersinia pseudotuberculosis to LC3-associated pathways involving single- or double-membrane vacuoles. Autophagy 2014-09-01 [PMID: 25046114] (WB)	WB
Wang WK, Lin ST, Chang WW et al. Hinokitiol induces autophagy in murine breast and colorectal cancer cells Environ Toxicol. 2014-07-12 [PMID: 25044443] (WB, Mouse)	WB	Mouse
Seguin SJ, Morelli FF, Vinet J et al. Inhibition of autophagy, lysosome and VCP function impairs stress granule assembly. Cell Death Differ. 2014-07-18 [PMID: 25034784]
Ma Dennis, Stokes Kyle, Mahngar Kevinjeet et al. Inhibition of stress induced premature senescence in presenilin-1 mutated cells with water soluble Coenzyme Q10. Mitochondrion. 2014-07-15 [PMID: 25034304] (WB, Human)	WB	Human
Chen S, Zhou L, Zhang Y et al. Targeting SQSTM1/p62 Induces Cargo-Loading Failure and Converts Autophagy to Apoptosis via NBK/Bik. Mol. Cell. Biol. 2014-07-07 [PMID: 25002530] (WB, Human) Details: LC3 antibody used for WB on several experiments involving human myeloma U266 cells and RPMI8226 cells.	WB	Human
Barnard RA, Wittenburg LA, Amaravadi RK et al. Phase I clinical trial and pharmacodynamic evaluation of combination hydroxychloroquine and doxorubicin treatment in pet dogs treated for spontaneously occurring lymphoma. Autophagy 2014-08-01 [PMID: 24991836] (WB)	WB
Feng L, Ma Y, Sun J et al. YY1-MIR372-SQSTM1 regulatory axis in autophagy. Autophagy 2014-08-01 [PMID: 24991827] (WB)	WB
Schenkel LC,Bakovic M. Palmitic Acid and Oleic Acid Differentially Regulate Choline Transporter-Like 1 Levels and Glycerolipid Metabolism in Skeletal Muscle Cells Lipids. 2014-06-28 [PMID: 24972900] (WB, Mouse) Details: LC3 antibody used for WB on lysates of Palmitic Acid (PAM) and Oleic Acid (OLA ) - treated C2C12 mouse myoblasts - 15 ug loading amount, 12 % SDS-PAGE denaturing gel, blocked with 5 % skim milk in PBS-T, primary - 1:1000 dilution in BSA ON 4C, secondary - horseradish peroxidase-conjugated anti-rabbit IgG, detected by chemiluminescent peroxidase substrate assay.	WB	Mouse
Owen KA, Meyer CB, Bouton AH, Casanova JE. Activation of Focal Adhesion Kinase by Salmonella Suppresses Autophagy via an Akt/mTOR Signaling Pathway and Promotes Bacterial Survival in Macrophages. PLoS Pathog. 2014-06-01 [PMID: 24901456] (WB, Mouse) Details: Salmonella/Pathogen-induced LC3 recruitment in peritoneal exudate macrophages (PEMs) from WT and FAK?/? mice was evaluated . WT and FAK-/- PEMs were incubated with S. typhimurium strain Delta-invG for 5 h with or without Bafilomycin A1 (300 ng) beforeimmunoblotting with LC3 antibody. (Figure 4E)	WB	Mouse
Bingol B, Tea JS, Phu L et al. The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy. Nature 2014-06-19 [PMID: 24896179] (ICC/IF, WB, Human)	ICC/IF, WB	Human
Zielniok K, Motyl T, Gajewska M. Functional Interactions between 17beta-Estradiol and Progesterone Regulate Autophagy during Acini Formation by Bovine Mammary Epithelial Cells in 3D Cultures. BioMed Research International. 2014-05-07 [PMID: 24895572] (WB, Bovine)	WB	Bovine
Alves S, Cormier-Dequaire F, Marinello M et al. The autophagy/lysosome pathway is impaired in SCA7 patients and SCA7 knock-in mice. Acta Neuropathol. 2014-05-24 [PMID: 24859968] (IHC-Fr, Mouse, Human)	IHC-Fr	Mouse, Human
Demos-Davies KM, Ferguson BS, Cavasin MA et al. HDAC6 contributes to pathological responses of heart and skeletal muscle to chronic angiotensin-II signaling Am J Physiol Heart Circ Physiol. 2014-05-22 [PMID: 24858848] (WB, Mouse)	WB	Mouse
Zeng Y, Li S, Wu J et al. Autophagy inhibitors promoted aristolochic acid I induced renal tubular epithelial cell apoptosis via mitochondrial pathway but alleviated nonapoptotic cell death in mouse acute aritolochic acid nephropathy model. Apoptosis. 2014 May 20 [PMID: 24841932] (WB, Mouse)	WB	Mouse
Chin RM, Fu X, Pai MY et al. The metabolite alpha-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR. Nature. 2014-05-14 [PMID: 24828042] (WB, Human)	WB	Human
Zavodszky E, Seaman MN, Moreau K et al. Mutation in VPS35 associated with Parkinson's disease impairs WASH complex association and inhibits autophagy. Nat Commun. 2014-05-13 [PMID: 24819384] (WB, Human)	WB	Human
Kang M, Jeong CW, Ku JH et al. Inhibition of autophagy potentiates atorvastatin-induced apoptotic cell death in human bladder cancer cells in vitro. Int J Mol Sci. 2014-05-12 [PMID: 24815071] (WB, ICC/IF, Human)	WB, ICC/IF	Human
Fang EF, Scheibye-Knudsen M, Brace LE et al. Defective Mitophagy in XPA via PARP-1 Hyperactivation and NAD(+)/SIRT1 Reduction. Cell. 2014-05-08 [PMID: 24813611] (ICC/IF, WB, Rat, Human, Mouse)	ICC/IF, WB	Rat, Human, Mouse
Basu S, Rajakaruna S, Reyes B et al. Suppression of MAPK/JNK-MTORC1 signaling leads to premature loss of organelles and nuclei by autophagy during terminal differentiation of lens fiber cells. Autophagy 2014-07-01 [PMID: 24813396] (WB)	WB
Yoon S, Han E, Choi YC et al. Inhibition of Cell Proliferation and Migration by miR-509-3p That Targets CDK2, Rac1, and PIK3C2A. Mol Cells 2014-04-01 [PMID: 24802056] (WB, Human)	WB	Human
Ruddy SC, Lau R, Cabrita MA et al. Preferential estrogen receptor beta ligands reduce Bcl-2 expression in hormone-resistant breast cancer cells to increase autophagy. Mol. Cancer Ther. 2014-04-30 [PMID: 24785256] (WB, Human)	WB	Human
Li BH, Yin YW, Liu Y et al. TRPV1 activation impedes foam cell formation by inducing autophagy in oxLDL-treated vascular smooth muscle cells. Cell Death Dis. 2014-04-18 [PMID: 24743737] (WB, Mouse)	WB	Mouse
Granato M, Lacconi V, Peddis M et al. Hepatitis C virus present in the sera of infected patients interferes with the autophagic process of monocytes impairing their in-vitro differentiation into dendritic cells. Biochim. Biophys. Acta 2014-03-28 [PMID: 24726834] (WB, Human)	WB	Human
BovE J, MartInez-Vicente M, Dehay B et al. BAX channel activity mediates lysosomal disruption linked to Parkinson disease Autophagy. 2014-05-11 [PMID: 24686337] (WB, Mouse)	WB	Mouse
Thorburn J, Andrysik Z, Staskiewicz L et al. Autophagy controls the kinetics and extent of mitochondrial apoptosis by regulating PUMA levels Cell Rep 2014-04-02 [PMID: 24685133] (WB, Human) Details: Citation using the Non-Recombinant Monoclonal format of this antibody.	WB	Human
Lin CJ, Chen TH, Yang LY, Shih CM. Resveratrol protects astrocytes against traumatic brain injury through inhibiting apoptotic and autophagic cell death. Cell Death Dis 2014-04-12 [PMID: 24675465] (WB, Rat)	WB	Rat
Ginet V, Spiehlmann A, Rummel C et al. Involvement of autophagy in hypoxic-excitotoxic neuronal death Autophagy. 2014-05-11 [PMID: 24674959] (WB, Rat)	WB	Rat
Guan B, Krokowski D, Majumder M et al. Translational control during endoplasmic reticulum stress beyond phosphorylation of the translation initiation factor eIF2a. J Biol Chem 2014-05-02 [PMID: 24648524] (WB, Mouse)	WB	Mouse
Kraft LJ, Nguyen TA, Vogel SS, Kenworthy AK Size, stoichiometry, and organization of soluble LC3-associated complexes. Autophagy 2014-05-01 [PMID: 24646892] (ICC/IF)	ICC/IF
Hung KC, Huang HJ, Lin MW et al. Roles of Autophagy in MPP+-Induced Neurotoxicity In Vivo: The Involvement of Mitochondria and a-Synuclein Aggregation. PLoS ONE 2014-03-20 [PMID: 24646838] (IHC-Fr, WB, Rat)	IHC-Fr, WB	Rat
Laker RC, Xu P, Ryall KA et al. A novel MitoTimer reporter gene for mitochondrial content, structure, stress and damage in vivo. J. Biol. Chem. 2014-03-18 [PMID: 24644293] (ICC/IF, Mouse)	ICC/IF	Mouse
Frieboes HB, Huang JS, Yin WC, McNally LR. Chloroquine-mediated cell death in metastatic pancreatic adenocarcinoma through inhibition of autophagy. JOP 2014-03-12 [PMID: 24618445] (WB, Human)	WB	Human
Dai DF, Karunadharma PP, Chiao YA et al. Altered proteome turnover and remodeling by short-term caloric restriction or rapamycin rejuvenate the aging heart. Aging Cell 2014-02-25 [PMID: 24612461] (WB, Mouse)	WB	Mouse
Wlodarska M, Thaiss CA, Nowarski R et al. NLRP6 Inflammasome Orchestrates the Colonic Host-Microbial Interface by Regulating Goblet Cell Mucus Secretion. Cell 2014-03-03 [PMID: 24581500] (WB, Mouse)	WB	Mouse
Farg MA, Sundaramoorthy V, Sultana JM et al. C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking. Hum Mol Genet. 2014-02-27 [PMID: 24549040] (WB, Human)	WB	Human
Jabir MS, Ritchie ND, Li D et al. Caspase-1 Cleavage of the TLR Adaptor TRIF Inhibits Autophagy and beta-Interferon Production during Pseudomonas aeruginosa Infection. Cell Host Microbe 2014-02-17 [PMID: 24528867] (WB, ICC/IF, Mouse, Human)	WB, ICC/IF	Mouse, Human
Pavlovic Z, Zhu L, Pereira L et al. Isoform-specific and PKC mediated regulation of CTP: phosphoethanolamine cytidylyltransferase phosphorylation. J. Biol. Chem. 2014-02-12 [PMID: 24519946] (WB, Human)	WB	Human
Thapaliya S, Runkana A, McMullen MR et al. Alcohol-induced autophagy contributes to loss in skeletal muscle mass. Autophagy 2014-04-01 [PMID: 24492484]
Ginet V, Puyal J, Rummel C et al. A critical role of autophagy in antileukemia/lymphoma effects of APO866, an inhibitor of NAD biosynthesis. Autophagy 2014-04-01 [PMID: 24487122] (WB, Human)	WB	Human
Nogalska A, D'Agostino C, Engel WK. Sodium phenylbutyrate reverses lysosomal dysfunction and decreases amyloid-B42 in an in vitro-model of inclusion-body myositis. Neurobiol. Dis. 2014-03-03 [PMID: 24472798] (WB, Human)	WB	Human
Larocque K, Ovadje P, Djurdjevic S et al. Novel analogue of colchicine induces selective pro-death autophagy and necrosis in human cancer cells. PLoS ONE 2014-01-27 [PMID: 24466327] (WB, Human)	WB	Human
Lee CH, Lin ST, Liu JJ et al. Salmonella induce autophagy in melanoma by the downregulation of AKT/mTOR pathway. Gene Ther. 2014-03-06 [PMID: 24451116] (WB, Mouse)	WB	Mouse
Lee E, Koo Y, Ng A et al. Autophagy is essential for cardiac morphogenesis during vertebrate development. Autophagy 2014-04-01 [PMID: 24441423] (WB)	WB
Mei W, Dong C, Hui C et al. Gambogenic Acid Kills Lung Cancer Cells through Aberrant Autophagy. PLoS ONE 2014-01-15 [PMID: 24427275] (WB, Human)	WB	Human
Kang JW, Cho HI, Lee SM. Melatonin Inhibits mTOR-Dependent Autophagy during Liver Ischemia/Reperfusion. Cell Physiol Biochem 2014-01-02 [PMID: 24401531] (WB, Mouse)	WB	Mouse
Xia Qing, Cai Yuchen, Peng Roujun et al. The CDK1 inhibitor RO3306 improves the response of BRCA-pro fi cient breast cancer cells to PARP inhibition. Int J Oncol. 2014-03-01 [PMID: 24378347] (Human)		Human
Baldo B, Soylu R, Petersen A et al. Maintenance of Basal Levels of Autophagy in Huntington’s Disease Mouse Models Displaying Metabolic Dysfunction. PLoS One 2013-12-20 [PMID: 24376631] (WB, Mouse)	WB	Mouse
Yun N, Cho HI, Lee SM. Impaired autophagy contributes to hepatocellular damage during ischemia/reperfusion: Heme oxygenase-1 as a possible regulator. Free Radic Biol Med 2013-12-22 [PMID: 24365205] (WB, Rat)	WB	Rat
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Kim Y, Kim Y S et al. BIX-01294 induces autophagy-associated cell death via EHMT2/G9a dysfunction and intracellular reactive oxygen species production. Autophagy 2013-01-12 [PMID: 24322755] (WB, Human)	WB	Human
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Samadder P, Bittman R, Byun HS, Arthur G et al. A glycosylated antitumor ether lipid kills cells via paraptosis-like cell death. Biochem Cell Biol 2009-04-01 [PMID: 19370058] (WB, Mouse, Human)	WB	Mouse, Human
Huang J, Canadien V, Lam GY et al. Activation of antibacterial autophagy by NADPH oxidases. PNAS;106(15):6226-6231. 2009-01-01 [PMID: 19339495] (WB, Mouse)	WB	Mouse
Tang D, Kang R, Xiao W et al. Quercetin prevents LPS-induced high-mobility group box 1 release and proinflammatory function. Am J Respir Cell Mol Biol;41(6):651-60. 2009-12-01 [PMID: 19265175]
Huttenhower C, Haley EM, Hibbs MA et al. Exploring the human genome with functional maps. Genome Res. 2009-02-26 [PMID: 19246570] (WB, Human) Details: Five genes - AP3B1, ATP6AP1, BLOC1S1, LAMP2, and RAB11A - are confirmed for their role in the initiation of macroautophagy in human fibroblasts through the utilization of a Bayesion integration system to provide funcitonal maps.	WB	Human
Sarkar S, Ravikumar B, Rubinsztein DC. Autophagic clearance of aggregate-prone proteins associated with neurodegeneration. Methods Enzymol 2009-01-01 [PMID: 19216903] (Rat)		Rat
Buzgariu W, Chera S, Galliot B. Methods to investigate autophagy during starvation and regeneration in hydra. Methods Enzymol 2008-01-01 [PMID: 19185734]
Sarkar S, Korolchuk V, Renna M et al. Methodological considerations for assessing autophagy modulators: a study with calcium phosphate precipitates. Autophagy;5(3):307-13. 2009-04-01 [PMID: 19182529]
Panyasrivanit M, Khakpoor A, Wikan N et al. Co-localization of constituents of the dengue virus translation replication machinery with amphisomes. J Gen Virol;90(Pt 2):448-56. 2009-02-01 [PMID: 19141455] (WB, Human)	WB	Human
Yuan H, Perry CN, Huang C et al. LPS-induced autophagy is mediated by oxidative signaling in cardiomyocytes and is associated with cytoprotection. Am J Physiol Heart Circ Physiol;296(2):H470-9. 2009-02-01 [PMID: 19098111] (ICC/IF, WB)	ICC/IF, WB
Pacheco CD, Elrick MJ, Lieberman AP. Tau deletion exacerbates the phenotype of Niemann-Pick type C mice implicates autophagy in pathogenesis. Hum Mol Genet;18(5):956-965. 2009-01-01 [PMID: 19074461] (WB, Mouse, Human)	WB	Mouse, Human
Li DD, Wang LL, Deng R et al. The pivotal role of c-Jun NH2-terminal kinase-mediated Beclin 1 expression during anticancer agents-induced autophagy in cancer cells. Oncogene 2009-02-12 [PMID: 19060920] (WB, Human)	WB	Human
Humbey O, Pimkina J, Zilfou JT et al. The ARF tumor suppressor can promote the progression of some tumors. Cancer Res;68(23):9608-13. 2008-12-01 [PMID: 19047137] (WB, Mouse)	WB	Mouse
Young JE, Martinez RA, La Spada AR. Nutrient deprivation induces neuronal autophagy and implicates reduced insulin signaling in neuroprotective autophagy activation. J Biol Chem;284(4):2363-73. 2009-01-23 [PMID: 19017649] (IF/IHC, WB, ICC/IF, Mouse)	IF/IHC, WB, ICC/IF	Mouse
Degtyarev M, De Maziere A, Orr C et al. Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents. J Cell Biol;183(1):101-16. 2008-10-06 [PMID: 18838554] (WB)	WB
Burdette DL, Yarbrough ML, Orvedahl A et al. Vibrio parahaemolyticus orchestrates a multifaceted host cell infection by induction of autophagy, cell rounding, then cell lysis. PNAS;105(34):12497-12502. 2008-01-01 [PMID: 18713860] (WB, Mouse)	WB	Mouse
Wong ES, Tan JM, Soong WE et al. Autophagy-mediated clearance of aggresomes is not a universal phenomenon. Hum Mol Genet;17(16):2570-82. 2008-08-15 [PMID: 18502787] (ICC/IF)	ICC/IF
Williams A, Sarkar S, Cuddon P et al. Novel targets for Huntington's disease in an mTOR-independent autophagy pathway. Nat Chem Biol 2008-05-01 [PMID: 18391949] (Human)		Human
Zhang H, Bosch-Marce M, Shimoda LA et al. Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia. J Biol Chem;283(16):10892-903. 2008-04-18 [PMID: 18281291] (WB, Mouse)	WB	Mouse
Miller BC, Zhao Z, Stephenson LM et al. The autophagy gene ATG5 plays an essential role in B lymphocyte development. Autophagy;4(3):309-14. 2008-04-01 [PMID: 18188005]
Sarkar S, Krishna G, Imarisio S et al. A rational mechanism for combination treatment of Huntington's disease using lithium and rapamycin. Hum Mol Genet;17(2):170-8. 2008-01-15 [PMID: 17921520] (WB)	WB
Settembre, C et al. A block of autophagy in lysosomal storage disorders. Hum Mol Genet;17(1):119-29. 2008-01-01 [PMID: 17913701] (ICC/IF, Mouse)	ICC/IF	Mouse
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