Novus Biologicals products are now on bio-techne.com

KA1/GRIK4/Glutamate Receptor KA1 Antibody - BSA Free

Images

 
Western Blot: KA1/GRIK4/Glutamate Receptor KA1 Antibody [NBP1-76851] - Rat brain lysate with Glutamate receptor KA1 antibody at (A) 0.5 (B) 1 and (C) 2 ug/ml.
Immunohistochemistry-Paraffin: KA1/GRIK4/Glutamate Receptor KA1 Antibody [NBP1-76851] - Human brain tissue using Glutamate receptor KA1 antibody at 2.5 ug/ml.
Immunocytochemistry/ Immunofluorescence: KA1/GRIK4/Glutamate Receptor KA1 Antibody [NBP1-76851] - Human Brain cells with Grik4 antibody at 20 ug/mL.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Concentration
1 mg/ml

Order Details

KA1/GRIK4/Glutamate Receptor KA1 Antibody - BSA Free Summary

Immunogen
Antibody was raised against a 18 amino acid synthetic peptide near the carboxy terminus of the mouse Grik4. The immunogen is located within the last 50 amino acids of Grik4. Amino Acid Squence: RPSPARSEESLEWDKTTN
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GRIK4
Purity
Peptide affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 20 ug/mL
  • Immunohistochemistry 2.5 ug/ml
  • Immunohistochemistry-Paraffin 2.5 ug/ml
  • Western Blot 0.5-2 ug/ml
Application Notes
Despite its predicted molecular weight, Grik4 often migrates at a lower molecular weight in SDS-PAGE.
Control Peptide
KA1/GRIK4/Glutamate Receptor KA1 Protein (NBP1-76851PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Peptide affinity purified

Alternate Names for KA1/GRIK4/Glutamate Receptor KA1 Antibody - BSA Free

  • EAA1
  • Excitatory amino acid receptor 1
  • GluK4
  • glutamate receptor KA1
  • Glutamate receptor KA-1
  • glutamate receptor, ionotropic kainate 4
  • glutamate receptor, ionotropic, kainate 4
  • GRIK4
  • KA1
  • KA1GRIK

Background

Grik4 codes for the KA1 subunit of kainate-type ionotropic glutamate receptors which are critical regulators of network activity that act by modifying neuronal excitability, directly and indirectly, through GABAergic interneurons. Five subunits can assemble to form kainate receptors (KARs): GluR5 (coded by Grik1), GluR6 (coded by Grik2), and GluR7 (coded by Grik3) are the low-affinity subunits, and KA1 and KA2 are the high-affinity subunits. In the adult brain, KARs are located pre- and postsynaptically on pyramidal cells and on interneurons. Kainate receptors on GABA-containing interneurons enhance GABA release and thereby downregulate glutamatergic signaling. KARs have been implicated in numerous psychiatric disorders. Case control studies show significant association of Grik4 with both schizophrenia and bipolar disorder. Despite its predicted molecular weight, Grik4 often migrates at a lower molecular weight in SDS-PAGE.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP1-76853
Species: Hu, Mu, Rt
Applications: ELISA, ICC/IF, IHC, IHC-P, WB
NBP3-16867
Species: Hu, Mu, Rt
Applications: IHC, IHC-P, WB
NBP2-61782
Species: Hu
Applications: ELISA, ICC/IF, WB
NBP1-76849
Species: Hu, Mu
Applications: ELISA, ICC/IF, IHC, IHC-P, WB
NLS921
Species: Bv, Hu
Applications: ICC, IHC, IHC-P, WB
NBP1-02312
Species: Hu
Applications: IHC, IHC-P, PEP-ELISA, WB
NBP2-75510
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-P, IP, WB
NB300-118
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-Fr, IHC-P, IP, WB
NLS892
Species: Bt, Bv, Ca, Ha, Hu, Mu, Po, Rb, Rt
Applications: ICC, IHC, IHC-P, WB
NBP2-22399
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, WB
NBP1-81567
Species: Hu
Applications: ICC/IF, IHC, IHC-P, WB
NBP3-17081
Species: Hu
Applications: IHC, IHC-P
NBP1-88790
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-P, WB
NLS3208
Species: Bv, Eq, Hu, Pm, Po, Pm
Applications: ICC, IHC, IHC-P, WB
NB300-106
Species: Hu, Mu, Rt
Applications: Flow, ICC/IF, IHC, IHC-Fr, IP, WB
H00000761-M02
Species: Hu, Mu
Applications: ELISA, Func, IHC, IHC-P, S-ELISA, WB
NB300-105
Species: Hu, Mu, Rb, Rt
Applications: IHC, IHC-P, IP, WB
NBP2-94573
Species: Hu, Mu
Applications: WB
NBP2-16684
Species: Hu, Mu, Rt
Applications: IHC, IHC-P, WB
NB300-107
Species: Hu, Mu, Rt
Applications: ICC/IF, IP, WB

Publications for KA1/GRIK4/Glutamate Receptor KA1 Antibody (NBP1-76851) (0)

There are no publications for KA1/GRIK4/Glutamate Receptor KA1 Antibody (NBP1-76851).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for KA1/GRIK4/Glutamate Receptor KA1 Antibody (NBP1-76851) (0)

There are no reviews for KA1/GRIK4/Glutamate Receptor KA1 Antibody (NBP1-76851). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for KA1/GRIK4/Glutamate Receptor KA1 Antibody (NBP1-76851) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional KA1/GRIK4/Glutamate Receptor KA1 Products

Research Areas for KA1/GRIK4/Glutamate Receptor KA1 Antibody (NBP1-76851)

Find related products by research area.

Blogs on KA1/GRIK4/Glutamate Receptor KA1

There are no specific blogs for KA1/GRIK4/Glutamate Receptor KA1, but you can read our latest blog posts.
mFluor Violet Conjugated Antibodies

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our KA1/GRIK4/Glutamate Receptor KA1 Antibody - BSA Free and receive a gift card or discount.

Bioinformatics

Gene Symbol GRIK4
Uniprot