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Glutamate Receptor 6 Antibody (4B4L9)

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Western Blot: Glutamate Receptor 6 Antibody (4B4L9) [NBP3-16867] - Western blot analysis of extracts of Mouse brain, using Glutamate Receptor 6 Rabbit mAb (NBP3-16867) at 1:1000 dilution. Secondary antibody: HRP Goat ...read more
Immunohistochemistry-Paraffin: Glutamate Receptor 6 Antibody (4B4L9) [NBP3-16867] - Immunohistochemistry of paraffin-embedded mouse kidney using Glutamate Receptor 6 Rabbit mAb (NBP3-16867) at dilution of 1:100 (40x ...read more
Western Blot: Glutamate Receptor 6 Antibody (4B4L9) [NBP3-16867] - Western blot analysis of extracts of 293T cells, using Glutamate Receptor 6 Rabbit mAb (NBP3-16867) at 1:1000 dilution. Secondary antibody: HRP Goat ...read more
Immunohistochemistry-Paraffin: Glutamate Receptor 6 Antibody (4B4L9) [NBP3-16867] - Immunohistochemistry of paraffin-embedded rat brain using Glutamate Receptor 6 Rabbit mAb (NBP3-16867) at dilution of 1:100 (40x ...read more
Immunohistochemistry-Paraffin: Glutamate Receptor 6 Antibody (4B4L9) [NBP3-16867] - Immunohistochemistry of paraffin-embedded human lung cancer using Glutamate Receptor 6 Rabbit mAb (NBP3-16867) at dilution of 1:100 ...read more

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC
Clone
4B4L9
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

Glutamate Receptor 6 Antibody (4B4L9) Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human Glutamate Receptor 6 (Q13002). MGAEELAFRFAVNTINRNRTLLPNTTLTYDTQKINLYDSFEASKKACDQLSLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWKHQVSDNKDSFYVSLY
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
GRIK2
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin
  • Western Blot 1:500 - 1:1000

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS, 0.05% BSA, 50% glycerol, pH7.3
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for Glutamate Receptor 6 Antibody (4B4L9)

  • EAA4
  • GLR6
  • GluK2
  • GLUK6
  • GluR6
  • glutamate receptor 6
  • glutamate receptor, ionotropic, kainate 2
  • ionotropic kainate 2
  • MGC74427
  • MRT6

Background

Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamategated, caution-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate, whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: epsilion 1, 2, 3, 4 and one zeta subunit. The zeta subunit is expressed throughout the brain stem, whereas the four epsilon subunits display limited distribution.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol GRIK2