KA2/GRIK5/Glutamate Receptor KA2 Antibody - BSA Free

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. Grik5, also known as kainate-preferring glutamate recptor subunit KA2, belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. Grik5 is highly homologous to the related ionotrophic glutamate receptor Grik4 (also known as KA1). Like Grik4, Grik5 does not form homomeric channels, but instead forms heteromers with Grik2. In Grik2- but not Grik1-null mice, Grik5 surface expression is greatly reduced in neurons, indicating that Grik2/Grik5 heteromers are required for exit from the endoplasmic reticulum to the cell surface. This Grik5 antibody does not cross-react with Grik4.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publication using NBP1-76853	Applications	Species
Sareddy GR, Pratap UP, Venkata PP, et al. Activation of estrogen receptor beta signaling reduces stemness of glioma stem cells Stem cells (Dayton, Ohio) 2021-01-20 [PMID: 33470499]

Array NBP1-76853

• KA2/GRIK5/Glutamate Receptor KA2 Antibodies
• KA2/GRIK5/Glutamate Receptor KA2 Proteins