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Integrin alpha L/CD11a Antibody (345913) [Fluorescein]

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Human peripheral blood lymphocytes were stained with Mouse Anti-Human Integrin aL/CD11a Fluorescein-conjugated Monoclonal Antibody (Catalog # FAB3595F, filled histogram) or isotype control antibody (Catalog # IC002F, open histogram). View our protocol for Staining Membrane-associated Proteins.
Human peripheral blood lymphocytes were stained with Mouse Anti-Human Integrin aL/CD11a Fluorescein-conjugated Monoclonal Antibody (Catalog # FAB3595F, filled histogram) or isotype control antibody (Catalog # IC002F, ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
345913
Clonality
Monoclonal
Host
Mouse
Conjugate
Fluorescein

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB3595U-100UG
Alexa Fluor 405
FAB3595V-100UG
Alexa Fluor 488
FAB3595G-100UG
Alexa Fluor 532
FAB3595X
Alexa Fluor 594
FAB3595T-100UG
Alexa Fluor 647
FAB3595R-100UG
Alexa Fluor 700
FAB3595N-100UG
Alexa Fluor 750
FAB3595S-100UG
Allophycocyanin/Cy7
FAB3595APCCY7
Biotin
FAB3595B
CoraFluor 1
FAB3595CL1
DyLight 350
FAB3595D
DyLight 405
FAB3595E
DyLight 488
FAB3595K
DyLight 550
FAB3595L
DyLight 594
FAB3595M
DyLight 650
FAB3595W
DyLight 680
FAB3595Y
DyLight 755
FAB3595Z
HRP
FAB3595H
Janelia Fluor 525
FAB3595JF525
Janelia Fluor 549
FAB3595I
Janelia Fluor 585
FAB3595JF585
Janelia Fluor 635
FAB3595JF635
Janelia Fluor 646
FAB3595J
Janelia Fluor 669
FAB3595JF669
PE/Atto594
FAB3595PEATT594
PE/Cy5.5
FAB3595PECY55
PE/Cy7
FAB3595PECY7
PerCP
FAB3595C
Unconjugated
MAB3595
mFluor Violet 450 SE
FAB3595MFV450
mFluor Violet 500 SE
FAB3595MFV500
mFluor Violet 610 SE
FAB3595MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB3595
Carrier Free
MAB3595
Carrier Free
MAB3595-SP
Carrier Free
FAB3595T-100UG
Carrier Free
FAB3595S-100UG
Carrier Free
FAB3595R-100UG
Carrier Free
FAB3595N-100UG
Carrier Free
FAB3595G-100UG
Carrier Free
FAB3595V-100UG
Carrier Free
FAB3595U-100UG
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Integrin alpha L/CD11a Antibody (345913) [Fluorescein] Summary

Immunogen
Chinese hamster ovary cell line CHO-derived recombinant human Integrin  alpha L/CD11a
Tyr26-Met1089 (Tyr660Ile)
Accession # CAA68747
Specificity
Detects human Integrin  alpha L/CD11a in Western blots.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
ITGAL
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Integrin alpha L/CD11a Antibody (345913) [Fluorescein]

  • CD11 antigen-like family member A
  • CD11a antigen
  • CD11a
  • CD11Aantigen CD11A (p180), lymphocyte function-associated antigen 1, alphapolypeptide
  • Integrin alpha L
  • integrin alpha-L
  • integrin gene promoter
  • integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen1; alpha polypeptide)
  • ITGAL
  • Leukocyte adhesion glycoprotein LFA-1 alpha chain
  • Leukocyte function-associated molecule 1 alpha chain
  • LFA-1 alpha
  • LFA-1
  • LFA1A
  • LFA-1A
  • Ly-15
  • Ly-21
  • lymphocyte function-associated antigen 1

Background

Integrin subunit alpha L/CD11a is a 180 kDa type I TM glycoprotein that interacts only with Integrin  beta 2/CD18 to form LFA-1, a leukocyte adhesion protein which binds endothelial cell ICAM-1 through -4. Human Integrin alpha L contains a 1064 aa extracellular domain (ECD), a 20 aa TM sequence and a 58 aa cytoplasmic domain. The ECD contains seven repeats that form a beta-propeller structure and one inserted vWA domain (I domain) containing a metal ion-dependent adhesion site (MIDAS). Human and mouse Integrin alpha L ECD share 74% aa identity. CD11a has two splice variants, one which contains a 53 aa insert after Gln954, and a second which shows a deletion of aa 110-192.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Integrin alpha
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FAB3595F
Integrin alpha L/CD11a Antibody (345913) [Fluorescein]
Species: Hu
Applications: Flow

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Bioinformatics

Gene Symbol ITGAL
Uniprot