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Insulin Receptor beta Antibody [DyLight 405]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications IHC, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 405

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-12793AF350
Alexa Fluor 405
NBP2-12793AF405
Alexa Fluor 488
NBP2-12793AF488
Alexa Fluor 532
NBP2-12793AF532
Alexa Fluor 594
NBP2-12793AF594
Alexa Fluor 647
NBP2-12793AF647
Alexa Fluor 700
NBP2-12793AF700
Alexa Fluor 750
NBP2-12793AF750
Allophycocyanin
NBP2-12793APC
Biotin
NBP2-12793B
CoraFluor 1
NBP2-12793CL1
DyLight 350
NBP2-12793UV
DyLight 488
NBP2-12793G
DyLight 550
NBP2-12793R
DyLight 594
NBP2-12793DL594
DyLight 650
NBP2-12793C
DyLight 680
NBP2-12793FR
DyLight 755
NBP2-12793IR
FITC
NBP2-12793F
HRP
NBP2-12793H
Janelia Fluor 525
NBP2-12793JF525
Janelia Fluor 549
NBP2-12793JF549
Janelia Fluor 646
NBP2-12793JF646
Janelia Fluor 669
NBP2-12793JF669
PE
NBP2-12793PE
PerCP
NBP2-12793PCP
Unconjugated
NBP2-12793
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Insulin Receptor beta Antibody [DyLight 405] Summary

Description
This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
Immunogen
The immunogen this antibody was made to, maps to a region between residue 1332 and 1382 of human Insulin Receptor, beta Subunit using the numbering given in entry NP_000199.2 (GeneID 3643).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
INSR
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Mouse reactivity reported from a verified customer review.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Insulin Receptor beta Antibody [DyLight 405]

  • CD220 antigen
  • CD220
  • EC 2.7.10
  • EC 2.7.10.1
  • HHF5
  • insulin receptor
  • IR

Background

The Insulin Receptor (InsR) is a heterodimeric receptor tyrosine kinase with an extracellular alpha-chain, a transmembrane domain and an intracellular beta-chain. InsR is activated upon binding of the peptide hormone insulin, leading to autophosphorylation of tyrosine residues 1146, 1150, and 1151 in the activation loop of the beta-chain. Additional autophosphorylation sites such as tyrosine residues 960, 972, 1316, and 1322 regulate the assembly of signal transduction complexes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol INSR