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Insulin R/CD220 Antibody (83-14) [Janelia Fluor® 635]

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Product Details

Summary
Reactivity Hu, Po, Bv, ShSpecies Glossary
Applications WB, ELISA, Flow, ICC/IF, IHC, IP
Clone
83-14
Clonality
Monoclonal
Host
Rabbit
Conjugate
Janelia Fluor 635

Order Details

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Insulin R/CD220 Antibody (83-14) [Janelia Fluor® 635] Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
This antibody was raised by immunizing mice with IM-9 lymphocytes followed by purified insulin receptor.
Specificity
Recognises the extracellular domain of the Insulin R/CD220. Amino acids 469 - 592 (exon 7 and 8) of Insulin R/CD220.
Isotype
IgG Kappa
Clonality
Monoclonal
Host
Rabbit
Gene
INSR
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Insulin R/CD220 Antibody (83-14) [Janelia Fluor® 635]

  • CD 220
  • CD220 antigen
  • CD220
  • EC 2.7.10
  • EC 2.7.10.1
  • HHF5
  • INSR
  • Insulin R
  • insulin receptor
  • InsulinR
  • IR

Background

Insulin receptor plays a major part in the regulation of glucose homeostasis, which when malfunctioning can result in diabetes and cancer. Encoded by the INSR gene, insulin receptor has two isoforms produced by alternative splicing, HIR-B and HIR-A.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Bioinformatics

Gene Symbol INSR