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INSRR/IR-related receptor Antibody (326929)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, CyTOF-ready
Clone
326929
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB3055U-100UG
Alexa Fluor 405
FAB3055V-100UG
Alexa Fluor 488
FAB3055G-100UG
Alexa Fluor 532
FAB3055X
Alexa Fluor 594
FAB3055T-100UG
Alexa Fluor 647
FAB3055R-100UG
Alexa Fluor 700
FAB3055N-100UG
Alexa Fluor 750
FAB3055S-100UG
Allophycocyanin
FAB3055A
Allophycocyanin/Cy7
FAB3055APCCY7
Biotin
FAB3055B
CoraFluor 1
FAB3055CL1
DyLight 350
FAB3055D
DyLight 405
FAB3055E
DyLight 488
FAB3055K
DyLight 550
FAB3055L
DyLight 594
FAB3055M
DyLight 650
FAB3055W
DyLight 680
FAB3055Y
DyLight 755
FAB3055Z
FITC
FAB3055F
HRP
FAB3055H
Janelia Fluor 525
FAB3055JF525
Janelia Fluor 549
FAB3055I
Janelia Fluor 585
FAB3055JF585
Janelia Fluor 635
FAB3055JF635
Janelia Fluor 646
FAB3055J
Janelia Fluor 669
FAB3055JF669
PE
FAB3055P
PE/Atto594
FAB3055PEATT594
PE/Cy5.5
FAB3055PECY55
PE/Cy7
FAB3055PECY7
PerCP
FAB3055C
mFluor Violet 450 SE
FAB3055MFV450
mFluor Violet 500 SE
FAB3055MFV500
mFluor Violet 610 SE
FAB3055MFV610
View Available Formulations
Catalog# & Formulation Size Price
Carrier Free
MAB3055-SP
Carrier Free
FAB3055V-100UG
Carrier Free
FAB3055U-100UG
Carrier Free
FAB3055T-100UG
Carrier Free
FAB3055S-100UG
Carrier Free
FAB3055R-100UG
Carrier Free
FAB3055N-100UG
Carrier Free
FAB3055G-100UG
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INSRR/IR-related receptor Antibody (326929) Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human INSRR
Leu24-Leu923
Accession # P14616
Specificity
Detects human INSRR in direct ELISAs and Western blots.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
INSRR
Purity Statement
Protein A or G purified from hybridoma culture supernatant
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry 2.5 ug/10^6 cells
  • Western Blot 1 ug/mL

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for INSRR/IR-related receptor Antibody (326929)

  • EC 2.7.10
  • EC 2.7.10.1
  • INSRR
  • insulin receptor-related protein
  • insulin receptor-related receptor
  • IRR
  • IRRIR-related receptor

Background

INSRR is a 175 kDa orphan receptor belonging to the insulin receptor subfamily of the receptor tyrosine kinase family. It is expressed in neuroblastoma and many adult tissues, including kidney, heart, pancreas, liver and skeletal muscle. INSRR is synthesized as a single chain type I transmembrane glycoprotein precursor and undergoes proteolytic processing to generate the mature disulfide linked alpha 2/ beta 2 tetrameric receptor. The alpha  subunit is localized extracellularly while the transmembrane beta  subunit contains an extracellular domain, a transmembrane segment and a cytoplasmic kinase domain. The extracellular domain of human INSRR shares approximately 90% amino acid sequence identity with mouse INSRR.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol INSRR
Uniprot