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INSRR/IR-related receptor Antibody (326903)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clone
326903
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

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Catalog# & Formulation Size Price
Carrier Free
MAB30551-SP
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INSRR/IR-related receptor Antibody (326903) Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human INSRR
Leu24-Leu923
Accession # P14616
Specificity
Detects human INSRR in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross‑reactivity with recombinant human Insulin receptor is observed.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
INSRR
Purity Statement
Protein A or G purified from hybridoma culture supernatant
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Applications/Dilutions

Dilutions
  • Western Blot 1 ug/mL
Publications
Read Publication using
MAB30551 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for INSRR/IR-related receptor Antibody (326903)

  • EC 2.7.10
  • EC 2.7.10.1
  • INSRR
  • insulin receptor-related protein
  • insulin receptor-related receptor
  • IRR
  • IRRIR-related receptor

Background

INSRR is a 175 kDa orphan receptor belonging to the insulin receptor subfamily of the receptor tyrosine kinase family.It is expressed in neuroblastoma and many adult tissues, including kidney, heart, pancreas, liver and skeletal muscle. INSRR is synthesized as a single chain type I transmembrane glycoprotein precursor and undergoes proteolytic processing to generate the mature disulfide linked alpha 2/ beta 2 tetrameric receptor. The alpha subunit is localized extracellularly while the transmembrane beta subunit contains an extracellular domain, a transmembrane segment and a cytoplasmic kinase domain. The extracellular domain of human INSRR shares approximately 90% amino acid sequence identity with the mouse protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for INSRR/IR-related receptor Antibody (MAB30551)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: IHC-P.


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Bioinformatics

Gene Symbol INSRR
Uniprot