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IL-17/IL-17A Antibody [Biotin]

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Product Details

Summary
Reactivity Hu, Mu, RMSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Biotin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP1-76337AF350
Alexa Fluor 405
NBP1-76337AF405
Alexa Fluor 488
NBP1-76337AF488
Alexa Fluor 532
NBP1-76337AF532
Alexa Fluor 594
NBP1-76337AF594
Alexa Fluor 647
NBP1-76337AF647
Alexa Fluor 700
NBP1-76337AF700
Alexa Fluor 750
NBP1-76337AF750
CoraFluor 1
NBP1-76337CL1
DyLight 350
NBP1-76337UV
DyLight 405
NBP1-76337V
DyLight 488
NBP1-76337G
DyLight 550
NBP1-76337R
DyLight 594
NBP1-76337DL594
DyLight 650
NBP1-76337C
DyLight 680
NBP1-76337FR
DyLight 755
NBP1-76337IR
FITC
NBP1-76337F
HRP
NBP1-76337H
Janelia Fluor 525
NBP1-76337JF525
Janelia Fluor 549
NBP1-76337JF549
Janelia Fluor 585
NBP1-76337JF585
Janelia Fluor 635
NBP1-76337JF635
Janelia Fluor 646
NBP1-76337JF646
Janelia Fluor 669
NBP1-76337JF669
PerCP
NBP1-76337PCP
Unconjugated
NBP1-76337
mFluor Violet 450 SE
NBP1-76337MFV450
mFluor Violet 500 SE
NBP1-76337MFV500
mFluor Violet 610 SE
NBP1-76337MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP1-76337
BSA Free
NBP1-76337
BSA Free
NBP1-76337-0.025mg
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IL-17/IL-17A Antibody [Biotin] Summary

Immunogen
Antibody was raised against a peptide corresponding to 16 amino acids near the center of mature human IL-17. The immunogen is located within amino acids 50-100 of IL-17.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
IL17A
Purity
Peptide affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Bovine: (84%), Rat: (81%). Use in Rhesus Macaque reported in scientific literature (PMID:32277724).

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Peptide affinity purified

Alternate Names for IL-17/IL-17A Antibody [Biotin]

  • CTLA8
  • CTLA-8
  • CTLA8cytotoxic T-lymphocyte-associated serine esterase 8
  • Cytotoxic T-lymphocyte-associated antigen 8
  • IL17
  • IL-17
  • IL17A
  • IL-17A
  • IL-17Acytotoxic T-lymphocyte-associated protein 8
  • IL-17CTLA-8
  • IL17interleukin-17A
  • interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)
  • interleukin 17A

Background

Interleukin 17 (IL-17) is a pro-inflammatory cytokine produced by TCRalpha/beta+ CD4 CD8 thymocytes, as well as by activated CD4+ and CD4+ CD45RO+ memory T cells (1). IL-17 stimulates the expression of TNFalpha, IL-1 beta, IL-6, and IL-8 (2). In addition, IL-17 is involved in the induction of inducible nitric oxide synthase and cyclooxygenase 2 in chondrocytes (3). High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis (4).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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IL-17/IL-17A
Antibody [Biotin]
NBP1-76337B
IL-17/IL-17A Antibody [Biotin]
Species: Hu, Mu, RM
Applications: WB, ELISA, ICC/IF, IHC

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for IL-17/IL-17A Antibody (NBP1-76337B). (Showing 1 - 2 of 2 FAQ).

  1. I want to stain some T cell subsets (Th17 and Th1), do you have antibodies for that? I need for flow cytometer in sheep or goat.
    • Unfortunately, we have neither a CD4 antibody nor an IL-17 antibody that has been validated in sheep or goat, although if you would like to try one you would again be eligible for our Innovators Reward Program. Please contact us at innovators@novusbio.com with any questions regarding this program.
  2. I'm looking to establish an ELISA for IL-17 and want your recommendation on which antibody pairs to buy. Least expensive ones, please. Also, I'd like the detection antibody to be fluorescently labeled.
    • Thank you for your patience while I reviewed our ELISA validated products for IL17. I was not sure what species you were going to be investigating, so I looked up our data for the human protein. If this is incorrect, just let me know and I can look up products for the species you will be working with. As for antibody pairs, we only had one set that have been tested together: Capture: NBP2-22531 Detection: NBP2-22532. The detection product is only available currently with a biotin conjugate. We can however offer custom conjugation for this product to any of our available conjugates. Please see the this link to see the available fluors. The typical fee for custom conjugation is usually about $80 additional. Once you know which fluor you would like, I can provide you with a quote. We do also offer several ELISA kits for this target (they typically employ HRP or Biotin detection systems, so I am not sure if they will work for your needs).

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol IL17A