IKK epsilon/IKBKE Antibody - BSA Free

Nuclear factor kappa B (NF-kappaB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kappaB mediates the expression of a great variety of genes in response to extracellular stimuli. NF-kappaB is associated with IkappaB proteins in the cell cytoplasm, which inhibit NF-kappaB activity. IkappaB is phosphorylated by IkappaB kinase (IKK) complex that contains IKKalpha, IKKbeta, and IKKgamma. A novel molecule in the IKK complex was recently identified and designated IKKepsilon/IKK-i. IKK epsilon is required for the activation of NF-kappaB by PMA and T cell receptors but not by TNFalpha and IL-1. IKKepsilon/IKK-i message is expressed in a variety of tissues and is inducible by TNFalpha, IL-1, and LPS.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: WB.

Showing Publication 1 - 1 of 1.

Publication using NBP1-76800	Applications	Species
Peant B, Diallo JS, Lessard L et al. Regulation of IkappaB kinase epsilon expression by the androgen receptor and the nuclear factor-kappaB transcription factor in prostate cancer. Mol Cancer Res. 2007-01-01 [PMID: 17259348] (WB, Human) Details: Imgenex antibodies cited [WB (human androgen-dependent prostate cancer cell lines), Figs. 1A, 3B, 4, 5A,B]: 1. IMG-5571 (IKK-epsilon) 2. IMG-139A (TBK-1).	WB	Human

Array NBP1-76800

• IKK epsilon/IKBKE Antibodies
• IKK epsilon/IKBKE Lysate
• IKK epsilon/IKBKE Proteins