NB100-64387 recognizes most isoforms of natural and recombinant murine alpha interferon. It does not cross-react with murine beta or gamma interferon, nor with human alpha interferon.
Isotype
IgG1
Clonality
Monoclonal
Host
Rat
Gene
IFNA1
Purity
Protein G purified
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Functional. The antibody exhibits neutralizing activity of approximately 6.25 x 10^4 neutralizing units/mg. Use in ELISA reported in scientific literature (PMID 25561542)
Publications
Read Publications using NB100-64387 in the following applications:
IFL;IFN;IFNA@;IFNA13;IFN-ALPHA;IFN-alphaD;Interferon alpha-1/13;leIF D
IFNA1
IFNalpha 1
IFN-alpha 1
Background
The type I interferons consist of 14 different alpha isoforms (subtypes with slightly different specificities), and single beta, omega, epsilon and kappa isoforms. Homologous molecules are found in many species, including rats and mice (and most mammals), and have been identified in birds, reptiles and fish species. Interferon alpha is produced primarily by plasmacytoid dendritic cells and is a potent component of the anti viral innate immune response; it modulates adaptive immunity.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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