Reactivity | HuSpecies Glossary |
Applications | WB, Flow, ICC/IF, IHC |
Clone | 2-48 |
Clonality | Monoclonal |
Host | Mouse |
Conjugate | DyLight 350 |
Immunogen | Purified recombinant human IFN-alpha 1 (Uniprot: P01562) |
Localization | Cytoplasmic & Extracellular (Secreted) |
Specificity | This monoclonal antibody is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1. |
Isotype | IgG1 Kappa |
Clonality | Monoclonal |
Host | Mouse |
Gene | IFNA1 |
Purity | Protein A or G purified |
Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
Dilutions |
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Application Notes | Optimal dilution of this antibody should be experimentally determined. |
Storage | Store at 4C in the dark. |
Buffer | 50mM Sodium Borate |
Preservative | 0.05% Sodium Azide |
Purity | Protein A or G purified |
Secondary Antibodies |
Isotype Controls |
Research Areas for IFN-alpha 1 Antibody (NBP3-08231UV)Find related products by research area.
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Gene Symbol | IFNA1 |