IFIT2 Antibody

Saha et al. used this antibody to study protein expression of murine GARG39/IFIT2 in relation to viral infection. Immunofluorescence localized this protein in association with the mitotic spindle in both mitotically active normal NIH3T3 and B16F10 melanoma cells. Western blotting shows approx. 55 kD band GARG39/IFIT2 in brain tissue of mice infected with Japanese encephalitis virus (JEV). Brain tissue from non-infected mice did not display this band. In 1994 Bluyssen et al. characterized the gene for murine GARG39/IFIT2 and historically the protein has been identified as interferon-induced protein with tetratricopeptide repeats 2 (IFIT-2), interferon-induced 54 kDa protein (IFI-54K), glucocorticoid-attenuated response gene 39 protein (GARG-39). Human IFIT2, with 62% amino acid sequence identity, has been referred to as Interferon-induced protein with tetratricopeptide repeats 2 (IFIT-2), Interferon-induced 54 kDa protein (IFI-54K) and ISG-54 K. Kang et al. showed with proteome analysis IFIT2 was expressed more than two-fold in human osteosarcoma cells U2OS treated with ascochlorin. Kawada et al. studied gene expression to show that IFIT2 is strongly upregulated in peripheral blood in children during the acute phase of influenza.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: WB.

Showing Publications 1 - 5 of 5.

Publications using NBP1-31164	Applications	Species
Khan KA TRK-Fused Gene (TFG), a protein involved in protein secretion pathways, is an essential component of the antiviral innate immune response PloS Pathog 2021-01-07 [PMID: 33411856] (WB, WB, Human)	WB, WB	Human
Khan KA, Do F, Marineau A et al. Fine-Tuning of the RIG-I-Like Receptor/Interferon Regulatory Factor 3-Dependent Antiviral Innate Immune Response by the Glycogen Synthase Kinase 3/beta-Catenin Pathway. Mol Cell Biol 2015-09-01 [PMID: 26100021]
Baril M, Es-Saad S, Chatel-Chaix L et al. Genome-wide RNAi Screen Reveals a New Role of a WNT/CTNNB1 Signaling Pathway as Negative Regulator of Virus-induced Innate Immune Responses. PLoS Pathog 2013-06-01 [PMID: 23785285] (WB, Human)	WB	Human
van Zuylen WJ, Doyon P, Clement JF et al. Proteomic profiling of the TRAF3 interactome network reveals a new role for the ER-to-Golgi transport compartments in innate immunity. PLoS Pathog 2012-01-01 [PMID: 22792062] (WB, Human)	WB	Human
Khowal S, Monga S, Naqvi S et al. Molecular winnowing, expressional analyses and interactome scrutiny of cellular proteomes of oral squamous cell carcinoma Advances in Cancer Biology - Metastasis 2021-10-01

Images	Ratings	Applications	Species	Date	Details
	5 reviewed by: Verified Customer	WB	Human	07/17/2015	View Summary Application Western Blot Sample Tested 293T, Hela, HEC-1-B, MRC-5 fibroblasts, whole cell extract following Senadi virus infection for 8-24h (200HAU/ml) Species Human
	5 reviewed by: Verified Customer	WB	Human	07/16/2015	View Summary Application Western Blot Sample Tested 293T Species Human

Array NBP1-31164

• IFIT2 Antibodies
• IFIT2 Lysate
• IFIT2 Proteins