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HYPB Antibody (OTI1E1) [DyLight 405]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications IHC
Clone
OTI1E1
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 405

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-71850AF350
Alexa Fluor 405
NBP2-71850AF405
Alexa Fluor 488
NBP2-71850AF488
Alexa Fluor 532
NBP2-71850AF532
Alexa Fluor 594
NBP2-71850AF594
Alexa Fluor 647
NBP2-71850AF647
Alexa Fluor 700
NBP2-71850AF700
Alexa Fluor 750
NBP2-71850AF750
Allophycocyanin
NBP2-71850APC
Biotin
NBP2-71850B
CoraFluor 1
NBP2-71850CL1
DyLight 350
NBP2-71850UV
DyLight 488
NBP2-71850G
DyLight 550
NBP2-71850R
DyLight 594
NBP2-71850DL594
DyLight 650
NBP2-71850C
DyLight 680
NBP2-71850FR
DyLight 755
NBP2-71850IR
FITC
NBP2-71850F
HRP
NBP2-71850H
Janelia Fluor 525
NBP2-71850JF525
Janelia Fluor 549
NBP2-71850JF549
Janelia Fluor 646
NBP2-71850JF646
Janelia Fluor 669
NBP2-71850JF669
PE
NBP2-71850PE
PerCP
NBP2-71850PCP
Unconjugated
NBP2-45791
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-45791
Azide and BSA Free
NBP2-71850
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HYPB Antibody (OTI1E1) [DyLight 405] Summary

Immunogen
Recombinant protein fragment corresponding to amino acids 1787-2144 of human HYPB (NP_054878) produced in E.coli.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
SETD2
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for HYPB Antibody (OTI1E1) [DyLight 405]

  • FLJ22472
  • FLJ23184
  • FLJ45883
  • FLJ46217
  • HIF1
  • HIF-1EC 2.1.1.43
  • HIP-1
  • histone-lysine N-methyltransferase SETD2
  • hSET2
  • huntingtin interacting protein 1
  • Huntingtin yeast partner B
  • Huntingtin-interacting protein 1
  • Huntingtin-interacting protein B
  • HYPBp231HBP
  • KIAA1732SET domain-containing protein 2
  • KMT3AHBP231
  • Lysine N-methyltransferase 3A
  • SET domain containing 2
  • SET2FLJ16420

Background

Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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HYPB Antibody
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NBP2-71850V
HYPB Antibody (OTI1E1) [DyLight 405]
Species: Hu, Mu, Rt
Applications: IHC

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Bioinformatics

Gene Symbol SETD2