Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IP
Host: Rabbit Polyclonal
Species: Hu
Applications: IHC
Host: Mouse Monoclonal
Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Mouse Monoclonal
Species: Hu
Applications: AC
Description
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. (provided by RefSeq)
Bioinformatics
| Entrez |
Mouse
Human
|
| Product By Gene ID |
29072 |
| Alternate Names |
- FLJ22472
- FLJ23184
- FLJ45883
- FLJ46217
- HIF1
- HIF-1EC 2.1.1.43
- HIP-1
- histone-lysine N-methyltransferase SETD2
- hSET2
- huntingtin interacting protein 1
- Huntingtin yeast partner B
- Huntingtin-interacting protein 1
- Huntingtin-interacting protein B
- HYPBp231HBP
- KIAA1732SET domain-containing protein 2
- KMT3AHBP231
- Lysine N-methyltransferase 3A
- SET domain containing 2
- SET2FLJ16420
|
