Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Human TL1A/TNFSF15 DuoSet ELISA, 5 Plate
MGC129934
MGC129935
TL1A
TL1Vascular endothelial cell growth inhibitor
TNF superfamily ligand TL1A
TNFSF15
tumor necrosis factor (ligand) superfamily, member 15
tumor necrosis factor ligand superfamily member 15
vascular endothelial growth inhibitor-192A
VEGI
VEGI192A
VEGITNF ligand-related molecule 1
Background
TL1A is a type II transmembrane protein belonging to the TNF superfamily and has been designated TNF superfamily member 15 (TNFSF15). TL1A is predominantly expressed in endothelial cells and its expression is inducible by TNF-alpha and IL-1alpha. TL1A binds with high affinity to death receptor 3 (DR3), now known as TNFRSF25. Depending on the cell context, ligation of DR3 by TL1A can trigger one of two signaling pathways, activation of the transcription factor NF-kB, or activation of caspases and apoptosis.