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HSD17B6 Antibody

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Orthogonal Strategies: Immunohistochemistry-Paraffin: HSD17B6 Antibody [NBP2-32431] - Staining in human liver and pancreas tissues using anti-HSD17B6 antibody. Corresponding HSD17B6 RNA-seq data are presented for ...read more
Immunohistochemistry-Paraffin: HSD17B6 Antibody [NBP2-32431] - Staining of human testis shows strong cytoplasmic positivity in Leydig cells.
Immunohistochemistry-Paraffin: HSD17B6 Antibody [NBP2-32431] - Staining of human liver shows high expression.
Immunohistochemistry-Paraffin: HSD17B6 Antibody [NBP2-32431] - Staining of human pancreas shows low expression as expected.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

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HSD17B6 Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to amino acids: VEPGYFRTGMTNMTQSLERMKQSWKEAPKHIKETYGQQYFDALYNIMKEGLL
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
HSD17B6
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:1000 - 1:2500
  • Immunohistochemistry-Paraffin 1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
HSD17B6 Protein (NBP2-32431PEP)
Publications
Read Publication using
NBP2-32431 in the following applications:

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for HSD17B6 Antibody

  • 17-beta-HSD 6
  • 17-beta-HSD6
  • 17-beta-hydroxysteroid dehydrogenase type 6
  • 3(alpha->beta)-hydroxysteroid epimerase
  • 3-alpha->beta-HSE
  • EC 1.1.1
  • EC 1.1.1.105
  • EC 1.1.1.62
  • EC 1.1.1.63
  • HSE3-hydroxysteroid epimerase
  • hydroxysteroid (17-beta) dehydrogenase 6 homolog (mouse)
  • hydroxysteroid (17-beta) dehydrogenase 6
  • NAD+ -dependent 3 alpha-hydroxysteroid dehydrogenase 3-hydroxysteroid epimerase
  • Oxidative 3-alpha hydroxysteroid dehydrogenase
  • oxidative 3-alpha-hydroxysteroid-dehydrogenase
  • oxidoreductase
  • retinol dehydrogenase
  • RODH3(alpha->beta)-hydroxysteroid epimerasel
  • SDR9C6
  • short chain dehydrogenase/reductase family 9C, member 6,3-alpha->beta-hydroxysteroid epimerase

Background

HSD17B6 is encoded by this gene has both oxidoreductase and epimerase activities and is involved in androgen catabolism. The oxidoreductase activity can convert 3 alpha-adiol to dihydrotestosterone, while the epimerase activity can convert androsterone to epi-androsterone. Both reactions use NAD+ as the preferred cofactor. This gene is a member of the retinol dehydrogenase family. Transcript variants utilizing alternative polyadenylation signals exist. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for HSD17B6 Antibody (NBP2-32431)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: IHC-P.


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Secondary Antibodies

 

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Bioinformatics

Gene Symbol HSD17B6