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HMGN3/TRIP7 Antibody

Images

 
Immunocytochemistry/ Immunofluorescence: HMGN3/TRIP7 Antibody [NBP1-86904] - Staining of human cell line U-2 OS shows localization to nucleoplasm.
Orthogonal Strategies: Immunohistochemistry-Paraffin: HMGN3/TRIP7 Antibody [NBP1-86904] - Staining in human fallopian tube and pancreas tissues using anti-HMGN3 antibody. Corresponding HMGN3 RNA-seq data are ...read more
Immunohistochemistry-Paraffin: HMGN3/TRIP7 Antibody [NBP1-86904] - Staining of human fallopian tube shows high expression.
Immunohistochemistry-Paraffin: HMGN3/TRIP7 Antibody [NBP1-86904] - Staining of human pancreas shows low expression as expected.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

Order Details

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HMGN3/TRIP7 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: KPEPKPRKTSAKKEPGAKISRGAKGKKEEKQEAGKEGTAPSENGETKAEEAQKTESVDNEGE
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
HMGN3
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:20 - 1:50
  • Immunohistochemistry-Paraffin 1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
HMGN3/TRIP7 Protein (NBP1-86904PEP)

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (84%)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for HMGN3/TRIP7 Antibody

  • DKFZp686E20226
  • high mobility group nucleosomal binding domain 3
  • high mobility group nucleosome-binding domain-containing protein 3
  • high-mobility group protein HMGN3
  • PNAS-25
  • thyroid hormone receptor interacting protein 7
  • thyroid hormone receptor interactor 7
  • Thyroid receptor-interacting protein 7
  • TR-interacting protein 7
  • TRIP-7
  • TRIP7FLJ42187

Background

Thyroid hormone receptors are hormone-dependent transcription factors that regulate expression of a variety of specific target genes. The protein encoded by this gene binds thyroid hormone receptor beta, but only in the presence of thyroid hormone. The encoded protein, a member of the HMGN protein family, is thought to reduce the compactness of the chromatin fiber in nucleosomes, thereby enhancing transcription from chromatin templates. Two transcript variants encoding different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

FAQs for HMGN3/TRIP7 Antibody (NBP1-86904) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol HMGN3