ABCA2 Antibody

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is highly expressed in brain tissue and may play a role in macrophage lipid metabolism and neural development. Two transcript variants encoding different isoforms have been found for this gene.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: IP, WB.

Showing Publications 1 - 3 of 3.

Publications using NBP1-20863	Applications	Species
A Po, A Citarella, G Catanzaro, ZM Besharat, S Trocchiane, F Gianno, C Sabato, M Moretti, E De Smaele, A Vacca, ME Fiori, E Ferretti Hedgehog-GLI signalling promotes chemoresistance through the regulation of ABC transporters in colorectal cancer cells Sci Rep, 2020-08-19;10(1):13988. 2020-08-19 [PMID: 32814794] (WB, Human)	WB	Human
Huang C, Zhang X, Jiang L et al. FoxM1 Induced Paclitaxel Resistance via Activation of the FoxM1/PHB1/RAF-MEK-ERK Pathway and Enhancement of the ABCA2 Transporter Mol Ther Oncolytics 2019-09-27 [PMID: 31334335] (WB, IP, Human)	WB, IP	Human
Mace S, Cousin E, Ricard S et al. ABCA2 is a strong genetic risk factor for early-onset Alzheimer's disease Neurobiol Dis 2005-02-01 [PMID: 15649702]

Array NBP1-20863

• ABCA2 Antibodies
• ABCA2 Protein